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3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione

3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione structure

CAS No.: 2990057-63-9

Chemical Name:: 3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione

Synonyms: 3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione;2,6-Piperidinedione, 3-(5-bromo-2-chlorophenyl)-

CBNumber:: CB316570422

Molecular Formula:: C11H9BrClNO2

Molecular Weight:: 302.55

MDL Number:

MOL File:: 2990057-63-9.mol

Last updated:2025-06-27 08:12:00

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3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione Properties

Boiling point	435.247±45.00 °C(Press: 760.00 Torr)(predicted)
Density	1.611±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	10.972±0.40(predicted)

3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione Chemical Properties,Uses,Production

Uses

3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

IC 50

Cereblon

References

[1] Mileti N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20(2):507-521. DOI:10.1021/acschembio.4c00812

3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione Suppliers

Global( 9)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Ruisi Pharmaceutical Technology Co., LTD	0531-0531-69900633 19963472814	changyuan20@163.com	China	9937	58
Birdo (Shanghai) Medical Technology Co., Ltd.	021-58099077-8041 18601625411	sales@birdotech.com	China	9379	58
Shanghai Fulaiyide Pharmaceutical Technology Co., Ltd	13382092506 15312065189	wang666xt@163.com	China	495	58
Wuhan Yuxiang Medical Technology Co., Ltd.	13971275651	sales@whyxpharma.com	China	1831	58
Shanghai Haohong Scientific Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	39718	58
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	9992	58
Chemyouth Life Science（Suzhou）Co.,Ltd	18605123100	kaiyuezhang@chemyouth.com	China	153	58
Tianjin Qige Technology Co., Ltd.	13012205621	304306732@qq.com	China	296	58
Xi'an Huarui Zhiyuan Biotechnology Co., Ltd.	18014474522	3487723181@qq.com	China	1166	58

Supplier	Advantage
Jinan Ruisi Pharmaceutical Technology Co., LTD	58
Birdo (Shanghai) Medical Technology Co., Ltd.	58
Shanghai Fulaiyide Pharmaceutical Technology Co., Ltd	58
Wuhan Yuxiang Medical Technology Co., Ltd.	58
Shanghai Haohong Scientific Co., Ltd.	58
Accela ChemBio Co.,Ltd.	58
Chemyouth Life Science（Suzhou）Co.,Ltd	58
Tianjin Qige Technology Co., Ltd.	58
Xi'an Huarui Zhiyuan Biotechnology Co., Ltd.	58

3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione 2,6-Piperidinedione, 3-(5-bromo-2-chlorophenyl)- 2990057-63-9