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METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE

CAS No.
53871-06-0
Chemical Name:
METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
Synonyms
METHYL 1-BENZHYDRYLAZETIDINE-3-CARBOXYLATE;BUTTPARK 37\04-18;Methyl 1-diphenylMethyl-a...;Methyl 1-(diphenylmethyl)-3-azetidinecarboxylate;METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE;N-BENZHYDRYLAZETIDINE-3-CARBOXYLIC ACID METHYL ESTER;1-BENZHYDRYL-AZETIDINE-3-CARBOXYLIC ACID METHYL ESTER;Methyl 1-diphenylmethyl-azetidine-3-carboxylate - [M1904];1-(Diphenylmethyl)azetidine-3-carboxylic acid methyl ester;3-AZETIDINECARBOXYLIC ACID, 1-(DIPHENYLMETHYL)-, METHYL ESTER
CBNumber:
CB3199020
Molecular Formula:
C18H19NO2
Molecular Weight:
281.35
MDL Number:
MFCD03407521
MOL File:
53871-06-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:50
Product description Number Pack Size Price
Methyl 1-benzhydrylazetidine-3-carboxylate 101197 1.00g $163
Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% M1904 10g $80
Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% M1904 25g $160
Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% M1904 50g $240
Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% M1904 100g $420

METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Properties

Melting point 67-70°C
Boiling point 366℃
Density 1.163
Flash point 122℃
storage temp. Sealed in dry,Room Temperature
pka 6.41±0.10(Predicted)
Appearance White to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2933998090

METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 101197 Methyl 1-benzhydrylazetidine-3-carboxylate 53871-06-0 1.00g $163 2026-05-18 Buy
Synthonix M1904 Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% 53871-06-0 10g $80 2026-05-06 Buy
Synthonix M1904 Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% 53871-06-0 25g $160 2026-05-06 Buy
Synthonix M1904 Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% 53871-06-0 50g $240 2026-05-06 Buy
Synthonix M1904 Methyl 1-diphenylmethyl-azetidine-3-carboxylate 97.0% 53871-06-0 100g $420 2026-05-06 Buy
Product number Packaging Price Buy
101197 1.00g $163 Buy
M1904 10g $80 Buy
M1904 25g $160 Buy
M1904 50g $240 Buy
M1904 100g $420 Buy

METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Chemical Properties,Uses,Production

Synthesis

1-Benzhydrylazetidine-3-carboxylic acid

36476-87-6

Iodomethane

74-88-4

METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE

53871-06-0

GENERAL STEPS: Potassium carbonate (6.53 g, 47.2 mmol) and iodomethane (0.976 mL, 15.7 mmol) were sequentially added to a solution of N,N-dimethylformamide (45 mL) of 1-diphenylmethylazetidine-3-carboxylic acid (4.20 g, 15.7 mmol) and the reaction was stirred at room temperature for 20.5 hours. After completion of the reaction, the reaction mixture was slowly poured into ice water and extracted with ethyl acetate (3 × 50 mL). The organic layers were combined, washed with saturated saline (50 mL) and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the resulting crude product was purified by silica gel column chromatography (elution gradient: heptane/ethyl acetate = 5:1 to 3:1). The fraction containing the target compound was collected and concentrated under reduced pressure to give methyl 1-diphenylmethylazetidine-3-carboxylate (3.57 g, 80.8% yield) as yellow crystals.1H NMR (400 MHz, CDCl3) δ: 3.26 (m, 2H), 3.31 (m, 1H), 3.44 (m, 2H), 3.69 (s, 3H), 4.38 (s, 1H), 7.16-7.16-7.16 1H), 7.16-7.20 (m, 2H), 7.25-7.28 (m, 4H), 7.39-7.41 (m, 4H). ESI-MS m/z: 282 [M + H]+.

References

[1] Patent: US2008/214815, 2008, A1. Location in patent: Page/Page column 14
[2] Patent: EP1889836, 2008, A1. Location in patent: Page/Page column 80

METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10821 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29794 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 +86-17392581500 1015@dideu.com China 3992 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Aromsyn Co., Ltd.
+86-0571-85585865 +8613336024896 CB@aromsyn.com China 19183 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49967 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58

View Lastest Price from METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE pictures 2020-02-14 METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
53871-06-0
US $1.00 / KG 1KG 99% 200kgs Career Henan Chemical Co

METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Spectrum

1-BENZHYDRYL-AZETIDINE-3-CARBOXYLIC ACID METHYL ESTER METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE BUTTPARK 37\04-18 METHYL 1-BENZHYDRYLAZETIDINE-3-CARBOXYLATE N-BENZHYDRYLAZETIDINE-3-CARBOXYLIC ACID METHYL ESTER Methyl 1-diphenylMethyl-a... Methyl 1-benzhydrylazetidine-3-carboxylate, Methyl 1-benzhydrylazetane-3-carboxylate 1-(Diphenylmethyl)azetidine-3-carboxylic acid methyl ester 3-AZETIDINECARBOXYLIC ACID, 1-(DIPHENYLMETHYL)-, METHYL ESTER Methyl 1-(diphenylmethyl)-3-azetidinecarboxylate Methyl 1-diphenylmethyl-azetidine-3-carboxylate - [M1904] 53871-06-0