tert-butyl 3-aminopropanoate
- CAS No.
- 15231-41-1
- Chemical Name:
- tert-butyl 3-aminopropanoate
- Synonyms
- Boc-C2-NH2;H-Beta-Ala-Otbu;tert-Butyl b-alaninate;6-Azetidinecarboxylicacid;b-Alanine tert-butyl ester;tert-butyl 3-aminopropanoate;β-Alanine,1,1-dimethylethylester;(5-phenylmethoxyoxan-5-yl)acetate;β-Alanine, 1,1-dimethylethyl ester;b-Alanine, 1,1-diMethylethyl ester
- CBNumber:
- CB32134799
- Molecular Formula:
- C7H15NO2
- Molecular Weight:
- 145.2
- MDL Number:
- MFCD06212562
- MOL File:
- 15231-41-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl 3-Aminopropanoate | B6504 | 200MG | $100 |
| tert-Butyl 3-Aminopropanoate | B6504 | 1G | $300 |
| tert-Butyl 3-Aminopropanoate | 467116 | 100mg | $355 |
| tert-Butyl3-Aminopropanoate | B699358 | 100mg | $85 |
| H-BETA-ALA-OTBU 95.00% | AAA0004670 | 1G | $896.21 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280-P304+P340-P305+P351+P338-P312 |
| HS Code | 2922498590 |
tert-butyl 3-aminopropanoate price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6504 | tert-Butyl 3-Aminopropanoate | 15231-41-1 | 200MG | $100 | 2025-07-31 | Buy |
| TCI Chemical | B6504 | tert-Butyl 3-Aminopropanoate | 15231-41-1 | 1G | $300 | 2025-07-31 | Buy |
| Usbiological | 467116 | tert-Butyl 3-Aminopropanoate | 15231-41-1 | 100mg | $355 | 2021-12-16 | Buy |
| TRC | B699358 | tert-Butyl3-Aminopropanoate | 15231-41-1 | 100mg | $85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AAA0004670 | H-BETA-ALA-OTBU 95.00% | 15231-41-1 | 1G | $896.21 | 2021-12-16 | Buy |
tert-butyl 3-aminopropanoate Chemical Properties,Uses,Production
Uses
tert-Butyl 3-Aminopropanoate is an intermediate useful in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
Synthesis
1116-98-9
15231-41-1
The general procedure for the synthesis of tert-butyl 3-aminopropionate from tert-butyl cyanoacetate is as follows: 200 g of tert-butyl cyanoacetate was added to the reactor, followed by the addition of 1 kg of 2% methanol-ammonia aqueous solution and 20 g of Ruannei nickel. The reaction kettle was sealed and replaced three times with nitrogen and then three times with hydrogen. The hydrogen pressure was adjusted to 5 MPa, heated to 55 °C, and the reaction was carried out under stirring for 6 h, during which the hydrogen was continuously replenished. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to about 200 g and diluted with ethyl acetate. After cooling, the pH was adjusted to 3 with ethyl acetate-hydrogen chloride solution, the reaction system was concentrated again and the precipitated solid was dried to give 198 g of the target product tert-butyl 3-aminopropionate.
IC 50
Alkyl/ether
References
[1] Patent: CN105367435, 2016, A. Location in patent: Paragraph 0022; 0023
tert-butyl 3-aminopropanoate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10238 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
View Lastest Price from tert-butyl 3-aminopropanoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | tert-butyl 3-aminopropanoate
15231-41-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2019-09-02 | tert-butyl 3-aminopropanoate
15231-41-1
|
US $1.00 / KG | 1KG | 98% | 200kg | Career Henan Chemical Co |
-
- tert-butyl 3-aminopropanoate
15231-41-1
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- tert-butyl 3-aminopropanoate
15231-41-1
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
