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Isophthalic dihydrazide

CAS No.
2760-98-7
Chemical Name:
Isophthalic dihydrazide
Synonyms
ISOPHTHALOHYDRAZIDE;Isophthaloyl hydrazide;m-Phthaloyldihydrazide;m-Phthalic dihydrazide;ISOPHTHALIC DIHYDRAZIDE;Isophthaloylbishydrazine;ISOPHTHALOYL DIHYDRAZIDE;IsophthalicDihydrazide>5-Methylisophthalohydrazide;Benzene-1,3-dicarbohydrazide
CBNumber:
CB3214444
Molecular Formula:
C8H10N4O2
Molecular Weight:
194.19
MDL Number:
MFCD00025117
MOL File:
2760-98-7.mol
MSDS File:
SDS
Last updated:2025-09-25 19:11:34

Isophthalic dihydrazide Properties

Melting point 224°C
Density 1.344±0.06 g/cm3(Predicted)
vapor pressure 0-0Pa at 20-25℃
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form Solid:particulate/powder
pka 11.87±0.10(Predicted)
color White to Almost white
InChI InChI=1S/C8H10N4O2/c9-11-7(13)5-2-1-3-6(4-5)8(14)12-10/h1-4H,9-10H2,(H,11,13)(H,12,14)
InChIKey UTTHLMXOSUFZCQ-UHFFFAOYSA-N
SMILES C(NN)(C1C=C(C=CC=1)C(NN)=O)=O
LogP -1.4 at 20℃ and pH7.1
Surface tension 74.4mN/m at 1g/L and 20℃
CAS DataBase Reference 2760-98-7(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances ISOPHTHALYL DIHYDRAZIDE
FDA UNII R51J8KL2JE
EPA Substance Registry System Isophthalic acid dihydrazide (2760-98-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315-H302
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29280000
NFPA 704
0
2 0

Isophthalic dihydrazide price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S547913 ISOPHTHALIC ACID DIHYDRAZIDE Aldrich 2760-98-7 250mg $179 2024-03-01 Buy
TCI Chemical I0257 Isophthalic Dihydrazide >95.0%(HPLC)(T) 2760-98-7 25g $39 2025-07-31 Buy
TCI Chemical I0257 Isophthalic Dihydrazide >95.0%(HPLC)(T) 2760-98-7 100g $89 2025-07-31 Buy
TCI Chemical I0257 Isophthalic Dihydrazide >95.0%(HPLC)(T) 2760-98-7 500g $220 2025-07-31 Buy
TRC I822010 Isophthalohydrazide 2760-98-7 250mg $45 2021-12-16 Buy
Product number Packaging Price Buy
S547913 250mg $179 Buy
I0257 25g $39 Buy
I0257 100g $89 Buy
I0257 500g $220 Buy
I822010 250mg $45 Buy

Isophthalic dihydrazide Chemical Properties,Uses,Production

Synthesis

Isophthalic dihydrazide is prepared by the reaction of Dimethyl isophthalate and Hydrazine hydrate. The specific synthesis steps are as follows:
A mixture of dimethyl ester of isophthalic acid (2.22 gm) and hydrazine hydrate (98percent, 2 cc) in methanol was refluxed for 5 hours and the reaction mixture was allowed to cool to room temperature. Then, the cooled reaction mixture was poured on to ice cold water. The dihydrazide of isophthalic acid thus obtained was filtered and recrystallized from ethanol. [1] Yield: (85percent), M.P=241℃, (Scheme1). 1HNMR (400 MHz, CDCL3, ppm): 9.81 (s, 2H, -CO-NH-), 8.20 (s 1H ), 7.8(d, 2H, J=7.6 Hz), 7.5 (t, 1H, 7.2 Hz), 4.5 (s, 4H).
Isophthalic dihydrazide synthesis

References

[1] Journal of the American Chemical Society, 2018,
[2] Bioorganic Chemistry, 2018, vol. 81, p. 389 - 395
[3] Pharmaceutical Chemistry Journal, 2001, vol. 35, # 12, p. 653 - 656
[4] Heterocyclic Communications, 2008, vol. 14, # 1-2, p. 101 - 105
[5] Organic and Biomolecular Chemistry, 2014, vol. 12, # 25, p. 4445 - 4453

Isophthalic dihydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 287)Suppliers
Supplier Tel Email Country ProdList Advantage
Finetech Industry Limited
+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9629 58
Hebei Chuanghai Biotechnology Co., Ltd
+8617732866630 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd
+8613288715578 sales@hbmojin.com China 12248 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13090 58
Henan Tianfu Chemical Co.,Ltd.
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Hefei TNJ Chemical Industry Co.,Ltd.
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career henan chemical co
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Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58

View Lastest Price from Isophthalic dihydrazide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isophthalic dihydrazide pictures 2025-09-25 Isophthalic dihydrazide
2760-98-7
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
Isophthalic dihydrazide pictures 2025-06-24 Isophthalic dihydrazide
2760-98-7
US $10.00 / KG 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
Isophthalic dihydrazide pictures 2021-07-13 Isophthalic dihydrazide
2760-98-7
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1,3-Bis(hydrazinocarbonyl)benzene Isophthaloylbishydrazine 1,3-Benzenedicarboxylicacid, 1,3-dihydrazide Isophthaloyl hydrazide 1,3-denzenedi carboxylic acid dihydrazide 5-Methylisophthalohydrazide Benzene-1,3-dicarbohydrazide ISOPHTHALOYL DIHYDRAZIDE ISOPHTHALIC DIHYDRAZIDE ISOPHTHALOHYDRAZIDE ISO-PHTHALIC ACID, DIHYDRAZIDE 1,3-Benzenedicarboxylicacid,dihydrazide 1,3-benzenedicarboxylicaciddihydrazide m-Phthaloyldihydrazide m-Phthalic dihydrazide IsophthalicDihydrazide> 2760-98-7 Pharmaceutical intermediates R00001