ChemicalBook >> CAS DataBase List >>3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol

3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol

CAS No.
70677-47-3
Chemical Name:
3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol
Synonyms
Canniprene;3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol;Phenol, 3-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-buten-1-yl)-
CBNumber:
CB32397271
Molecular Formula:
C21H26O4
Molecular Weight:
342.43
MDL Number:
MOL File:
70677-47-3.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:04
Product description Number Pack Size Price
Canniprene ≥98% CFN97198 5mg $553

3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Properties

Boiling point 500.3±45.0 °C(Predicted)
Density 1.128±0.06 g/cm3(Predicted)
form Solid
pka 9.63±0.10(Predicted)
color White to off-white
FDA UNII 95QD8NF292

3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Arctom CFN97198 Canniprene ≥98% 70677-47-3 5mg $553 2021-12-16 Buy
Product number Packaging Price Buy
CFN97198 5mg $553 Buy

3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Chemical Properties,Uses,Production

Uses

Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins[1].

IC 50

5-LO: 0.4 μM (IC50); PGE2: 10 μM (IC50)

References

[1] Allegrone G, et al. The Bibenzyl Canniprene Inhibits the Production of Pro-Inflammatory Eicosanoids and Selectively Accumulates in Some Cannabis sativa Strains. J Nat Prod. 2017 Mar 24;80(3):731-734. DOI:10.1021/acs.jnatprod.6b01126

6346-05-0
70677-47-3
Synthesis of 3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol from 3-Benzyloxy-4-methoxybenzaldehyde

3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Preparation Products And Raw materials

Raw materials

Preparation Products

3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Suppliers

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3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Canniprene Phenol, 3-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-buten-1-yl)- 70677-47-3