Methyl 2-hydroxyethyl cellulose
- CAS No.
- 9032-42-2
- Chemical Name:
- Methyl 2-hydroxyethyl cellulose
- Synonyms
- HEMC;Hydroxyethyl Methyl Cellulose(Hemc);HYDROXYETHYL METHYL CELLULOSE;METHYL HYDROXYETHYL CELLULOSE;Hymetellose;CID 133126848;Hymetellose328; MH 1000;'Tylose'® MH 300;Tylose? MH 300
- CBNumber:
- CB3241871
- Molecular Formula:
- C2H6O2·xCH4O·x
- Molecular Weight:
- 0
- MDL Number:
- MFCD00147597
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Tylose′? MH 300 viscosity 150-450 mPa.s, 2 % in H2O(20 °C) | 93800 | 1kg | $332 |
| Methylhydroxyethylcellulose for synthesis | 8.22069 | 100g | $44.5 |
| Methylhydroxyethylcellulose for synthesis | 8.22069 | 500g | $164 |
| Methyl 2-hydroxyethyl cellulose | 435015 | 250g | $82.6 |
| Tylose′? MH 300 viscosity 150-450 mPa.s, 2 % in H2O(20 °C) | 93800 | 250g | $101 |
| More product size | |||
| bulk density | 350kg/m3 |
|---|---|
| Density | 1.28-1.30 g/cm3 (20℃) |
| storage temp. | Store below +30°C. |
| solubility | H2O: 20 mg/mL, soluble |
| form | powder |
| color | white to faint beige |
| Viscosity | 600-1500mPa.s2% in H2O(20°C) |
| Water Solubility | H2O: soluble 20mg/mL |
| Cosmetics Ingredients Functions |
EMULSION STABILISING VISCOSITY CONTROLLING LIGHT STABILIZER |
| Cosmetic Ingredient Review (CIR) | Methyl 2-hydroxyethyl cellulose (9032-42-2) |
| InChIKey | JTWZVKMWOCBJEV-RXUSYSPUSA-N |
| FDA UNII |
HYMETELLOSE (50 MPA.S) (0MGW7Q3QG4) HYMETELLOSE (350 MPA.S) (12OT2LF5QH) HYMETELLOSE (17000 MPA.S) (15I0LMG04F) HYMETELLOSE (4150 MPA.S) (UVP539BB9Q) |
| EPA Substance Registry System | Cellulose, 2-hydroxyethyl methyl ether (9032-42-2) |
| UNSPSC Code | 12352201 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 1 |
| Autoignition Temperature | >360 °C |
| TSCA | TSCA listed |
| HS Code | 3912 39 85 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
Methyl 2-hydroxyethyl cellulose price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93800 | Tylose′? MH 300 viscosity 150-450 mPa.s, 2 % in H2O(20 °C) | 9032-42-2 | 1kg | $332 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.22069 | Methylhydroxyethylcellulose for synthesis | 9032-42-2 | 100g | $44.5 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.22069 | Methylhydroxyethylcellulose for synthesis | 9032-42-2 | 500g | $164 | 2025-07-31 | Buy |
| Sigma-Aldrich | 435015 | Methyl 2-hydroxyethyl cellulose | 9032-42-2 | 250g | $82.6 | 2025-07-31 | Buy |
| Sigma-Aldrich | 93800 | Tylose′? MH 300 viscosity 150-450 mPa.s, 2 % in H2O(20 °C) | 9032-42-2 | 250g | $101 | 2025-07-31 | Buy |
Methyl 2-hydroxyethyl cellulose Chemical Properties,Uses,Production
Chemical Properties
soluble in cold water, flocculates at elevated temperatures
Chemical Properties
A white, yellowish-white or grayish-white powder or granules, hygroscopic after drying.
Uses
Water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.
Pharmaceutical Applications
Hydroxyethylmethyl cellulose is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations. It has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.
Safety
Hydroxyethylmethyl cellulose is used as an excipient in various oral and topical pharmaceutical preparations, and is generally regarded as an essentially nontoxic and nonirritant material.
Synthesis
Hydroxyethyl methyl cellulose is prepared from refined cotton using ethylene oxide and chloromethane as etherifying agents. Steps: 1) A mixture of toluene and isopropanol, water, and NaOH are added to the reactor, heated and held. 2) Temperature is lowered, refined cotton is added, solvent is sprayed, vacuum is applied and nitrogen is purged for displacement, then alkalization is performed. 3) Vacuum is applied, ethylene oxide and chloromethane are added. Etherification occurs in two stages with controlled temperature and pressure. 4) The mixture is pressed into a desolvation kettle containing glacial acetic acid for neutralization. Temperature is raised for desolvation, and pH is adjusted. 5) Centrifugal separation, then transfer to a washing kettle for washing. 6) After centrifugation, the material is fed into a dryer, dried, crushed, and packaged.
storage
Hydroxyethylmethyl cellulose is hygroscopic and should therefore be stored under dry conditions away from heat.
Regulatory Status
GRAS listed. Included in nonparenteral medicines licensed in Europe (oral suspensions, tablets, and topical preparations).
Methyl 2-hydroxyethyl cellulose Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hehua Chemical Co.，Ltd | +86-15800509834 +86-15800509834 | sales@hehuachemical.com | China | 121 | 58 |
| Nantong Chem-land Co.,Ltd. | +undefined13862903883 | sales@chem-land.com | China | 61 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3995 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Hangzhou Bayee Chemical Co., Ltd. | 0086-571-86990109 | rachelhoo@bayeechem.com | China | 104 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
View Lastest Price from Methyl 2-hydroxyethyl cellulose manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-04 | Methyl 2-hydroxyethyl cellulose
9032-42-2
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-12-24 | Methyl 2-hydroxyethyl cellulose
9032-42-2
|
US $0.10 / KG | 1KG | 99.0% | 1000Tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-10-13 | Methyl 2-hydroxyethylcellulose
9032-42-2
|
US $2.00-6.00 / KG | 1KG | 99% | g-kg-tons | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- Methyl 2-hydroxyethyl cellulose
9032-42-2
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Methyl 2-hydroxyethyl cellulose
9032-42-2
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 2-hydroxyethylcellulose
9032-42-2
- US $2.00-6.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
