2-Methyl-3-thiophenecarboxylic acid methyl ester
- CAS No.
- 53562-51-9
- Chemical Name:
- 2-Methyl-3-thiophenecarboxylic acid methyl ester
- Synonyms
- Methyl 2-methylthiophene-3-carboxylate;Methyl 2-Methyl-3-thiophenecarboxylate;2-Methyl-3-thiophenecarboxylic acid methyl ester;3-Thiophenecarboxylic acid, 2-methyl-, methyl ester;2-Methyl-3-thiophenecarboxylic acid methyl ester ISO 9001：2015 REACH
- CBNumber:
- CB32474394
- Molecular Formula:
- C7H8O2S
- Molecular Weight:
- 156.2
- MDL Number:
- MFCD12026360
- MOL File:
- 53562-51-9.mol
- MSDS File:
- SDS
| Boiling point | 90-91 °C(Press: 17 Torr) |
|---|---|
| Density | 1.173±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C7H8O2S/c1-5-6(3-4-10-5)7(8)9-2/h3-4H,1-2H3 |
| InChIKey | CCNDEWOBDKZGAD-UHFFFAOYSA-N |
| SMILES | C1(C)SC=CC=1C(OC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330 |
| RIDADR | 1993 |
| HazardClass | 3 |
| PackingGroup | Ⅲ |
| HS Code | 2934999090 |
2-Methyl-3-thiophenecarboxylic acid methyl ester price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR905711 | Methyl 2-methylthiophene-3-carboxylate >97% | 53562-51-9 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR905711 | Methyl 2-methylthiophene-3-carboxylate >97% | 53562-51-9 | 5g | $77 | 2026-06-04 | Buy |
| Apolloscientific | OR905711 | Methyl 2-methylthiophene-3-carboxylate >97% | 53562-51-9 | 25g | $364 | 2026-06-04 | Buy |
| Apolloscientific | OR905711 | Methyl 2-methylthiophene-3-carboxylate >97% | 53562-51-9 | 100g | $1309 | 2026-06-04 | Buy |
| Activate Scientific | AS34061 | Methyl 2-methylthiophene-3-carboxylate 97% | 53562-51-9 | 1g | $67 | 2026-06-04 | Buy |
2-Methyl-3-thiophenecarboxylic acid methyl ester Chemical Properties, Uses, Production
Synthesis
67-56-1
1918-78-1
53562-51-9
General procedure for the synthesis of methyl 2-methyl-3-thiophenecarboxylate from methanol and 2-methyl-3-thiophenecarboxylic acid: thionyl chloride (200 mL, 2.76 mol) was added slowly and dropwise to a solution of 2-methyl-3-thiophenecarboxylic acid (100 g, 703 mmol) in methanol (500 mL). After stirring the reaction mixture under reflux conditions for 3 h, it was concentrated under reduced pressure. The concentrated residue was diluted with dichloromethane, washed sequentially with water, saturated aqueous sodium bicarbonate solution and brine, and then dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to give 105 g (96% yield) of methyl 2-methyl-3-thiophenecarboxylate as a brown oil. Its NMR hydrogen spectrum (400 MHz, CDCl3) data were as follows: δ 7.38 (d, J = 5.4 Hz, 1H), 6.98 (d, J = 5.4 Hz, 1H), 3.85 (s, 3H), 2.74 (s, 3H); Mass Spectrometry (ESI) m/z: 157 (M + H)+.
References
[1] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 269 - 294
[2] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 18, p. 5417 - 5422
[3] European Journal of Medicinal Chemistry, 2015, vol. 102, p. 471 - 476
[4] Journal of Medicinal Chemistry, 1995, vol. 38, # 24, p. 4806 - 4820
[5] Patent: US2012/101137, 2012, A1. Location in patent: Page/Page column 14
2-Methyl-3-thiophenecarboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Modachem Shanghai Co., Ltd | +86 (0)21 51320687 51371369 1744605818 | China | 1576 | 58 | |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
View Latest Price from 2-Methyl-3-thiophenecarboxylic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2-Methyl-3-thiophenecarboxylic acid methyl ester
53562-51-9
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-12-20 | 2-Methyl-3-thiophenecarboxylic acid methyl ester
53562-51-9
|
$1.00 | 1KG | 97-99% | 10000KGS | Career Henan Chemical Co |
-
- 2-Methyl-3-thiophenecarboxylic acid methyl ester
53562-51-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Methyl-3-thiophenecarboxylic acid methyl ester
53562-51-9
- $1.00
- 97-99%
- Career Henan Chemical Co
