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2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione structure

CAS No.: 153171-22-3

Chemical Name:: 2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione

Synonyms: 132582;N-(4-Bromobenzyl)phthalimide;2-(4-broMobenzyl)isoindoline-1,3-dione;2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione;2-[(4-bromophenyl)methyl]isoindole-1,3-dione;2-[(4-Bromophenyl)methyl]-1H-isoindol-1,3(2H)-dione;2-[(4-Bromophenyl)methyl]-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 2-[(4-bromophenyl)methyl]-

CBNumber:: CB32524323

Molecular Formula:: C15H10BrNO2

Molecular Weight:: 316.15

MDL Number:: MFCD04210206

MOL File:: 153171-22-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
2-(4-Bromobenzyl)isoindoline-1,3-dione	0507CE	250mg	$139
2-(4-BROMOBENZYL)ISOINDOLINE-1,3-DIONE 95.00%	HCH0362639	5MG	$500.42
2-(4-Bromobenzyl)isoindoline-1,3-dione 95+%	CD11249109	5g	$544
2-(4-Bromobenzyl)-1H-isoindole-1,3(2H)-dione 95%	CM147532	5g	$593
2-(4-Bromobenzyl)isoindoline-1,3-dione	153171223	1g	$172.8

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2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione Properties

Melting point	133 °C
Boiling point	445.7±28.0 °C(Predicted)
Density	1.604±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	-2.29±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	0507CE	2-(4-Bromobenzyl)isoindoline-1,3-dione	153171-22-3	250mg	$139	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0362639	2-(4-BROMOBENZYL)ISOINDOLINE-1,3-DIONE 95.00%	153171-22-3	5MG	$500.42	2021-12-16	Buy
Crysdot	CD11249109	2-(4-Bromobenzyl)isoindoline-1,3-dione 95+%	153171-22-3	5g	$544	2021-12-16	Buy
Chemenu	CM147532	2-(4-Bromobenzyl)-1H-isoindole-1,3(2H)-dione 95%	153171-22-3	5g	$593	2021-12-16	Buy
Alichem	153171223	2-(4-Bromobenzyl)isoindoline-1,3-dione	153171-22-3	1g	$172.8	2021-12-16	Buy

Product number	Packaging	Price	Buy
0507CE	250mg	$139	Buy
HCH0362639	5MG	$500.42	Buy
CD11249109	5g	$544	Buy
CM147532	5g	$593	Buy
153171223	1g	$172.8	Buy

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione Chemical Properties,Uses,Production

Synthesis

1074-82-4

589-15-1

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione

153171-22-3

(a) A reaction mixture of p-bromobenzyl bromide (4.00 g, 16.004 mmol) and phthalimide potassium salt (3.26 g, 17.61 mmol) in N,N-dimethylformamide (DMF, 10 mL) was subjected to an oil bath at 100 °C, CaCl2 was added as a desiccant, and the reaction was stirred for 6 hours. After completion of the reaction, the reaction was cooled to room temperature, the reaction was quenched by the addition of deionized water (100 mL), and the reaction mixture was extracted with ethyl acetate (AcOEt, 100 mL x 3). The organic phases were combined, washed sequentially with deionized water (100 mL×1) and saturated saline (100 mL×1), dried over anhydrous sodium sulfate (Na2SO4), filtered, and concentrated under reduced pressure to afford 2-(4-bromobenzyl)isoindoline-1,3-dione (5.28 g, quantitative yield) as a colorless solid. Colorless cottony crystals were obtained by recrystallization from hexane/ethyl acetate mixed solvent. Melting point 126-129 °C. 1H NMR (300 MHz, CDCl3) δ 4.80 (2H, s, CH2), 7.32 (2H, d, J = 7.8 Hz, ArH), 7.44 (2H, d, J = 8.1 Hz, ArH), 7.71-7.73 (2H, m, ArH), 7.84-7.85 (2H, m, ArH ).

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 14, p. 3720 - 3731
[2] Chemistry - A European Journal, 2010, vol. 16, # 33, p. 10171 - 10177
[3] Journal of the Chemical Society, 1931, p. 1225,1232
[4] Tetrahedron, 1993, vol. 49, # 43, p. 9855 - 9866
[5] Patent: WO2015/103317, 2015, A1. Location in patent: Page/Page column 271

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione Preparation Products And Raw materials

Raw materials

1H-Isoindol-1-one, 3-hydroxy- N-Hydroxyphthalimide Potassium phthalimide Phthalic anhydride 4-Bromobenzylamine hydrochloride

4-Bromotoluene 4-Bromobenzyl bromide

1of2

Preparation Products

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione Suppliers

Global( 32)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30227	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	+8618235132063	sales@tihondan.com	China	3767	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13913916777	info@chemlin.com.cn	China	16055	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42934	64
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	025-58196018 800028039	sales@fartop.net	China	2229	55
Shanghai Worldyang Chemical Co.,Ltd.	021-021-56795766	sales@worldyachem.com	China	9478	58
Zhengzhou Guancheng Laboratory equipment Sales	0371-88888888 272369594	2723695949@qq.com	China	4990	50
Chengdu Xiaojia Technology Co., Ltd.	15902830537	zhanghao@happysyn.com	China	3151	55

Supplier	Advantage
Career Henan Chemica Co	58
Labnetwork lnc.	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	58
Amadis Chemical Company Limited	58
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	55
Shanghai Worldyang Chemical Co.,Ltd.	58
Zhengzhou Guancheng Laboratory equipment Sales	50
Chengdu Xiaojia Technology Co., Ltd.	55

2-(4-bromobenzyl)-1H-isoindole-1,3(2H)-dione 2-(4-broMobenzyl)isoindoline-1,3-dione 132582 1H-Isoindole-1,3(2H)-dione, 2-[(4-bromophenyl)methyl]- 2-[(4-bromophenyl)methyl]isoindole-1,3-dione N-(4-Bromobenzyl)phthalimide 2-[(4-Bromophenyl)methyl]-1H-isoindole-1,3(2H)-dione 2-[(4-Bromophenyl)methyl]-1H-isoindol-1,3(2H)-dione 153171-22-3 alkyl bromide