ChemicalBook >> CAS DataBase List >>Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
- CAS No.
- 136285-65-9
- Chemical Name:
- Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
- Synonyms
- Azilsartan impurity Z;Azilsartan Impurity 113;Candesartan Impurity 16;Nicotinamide Impurity 62;Candesartan ester intermediate C3;2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate;Ethyl 2-[(t-butoxycarbonyl)amino]-3-nitrobenzoate;Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate;Ethyl-2-(tertiary butoxy carbonyl aMino)-3-nitro benzoate;ETHYL-2-T-BUTOXY-2-CARBOXYLAMINO-3-NITROBENZOATE 136285-65-9
- CBNumber:
- CB32537307
- Molecular Formula:
- C14H18N2O6
- Molecular Weight:
- 310.3
- MDL Number:
- MFCD09833364
- MOL File:
- 136285-65-9.mol
- MSDS File:
- SDS
Last updated:2025-09-25 17:15:13
| Product description | Number | Pack Size | Price |
| ETHYL-2-TERT-BUTOXY-2-CARBOXYLAMINO-3-NITROBENZOATE 95.00% | CHM0384465 | 5MG | $498.32 |
| Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | A884767 | 100g | $578 |
| Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | A884767 | 500g | $2125 |
| Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | A884767 | 1g | $26 |
| Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | A884767 | 5g | $87 |
| More product size | |||
| Boiling point | 390.8±32.0 °C(Predicted) |
|---|---|
| Density | 1.268 |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 12.00±0.70(Predicted) |
| Appearance | Light yellow to green yellow Solid |
| InChI | InChI=1S/C14H18N2O6/c1-5-21-12(17)9-7-6-8-10(16(19)20)11(9)15-13(18)22-14(2,3)4/h6-8H,5H2,1-4H3,(H,15,18) |
| InChIKey | NYCBXLQKKUBOGV-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C1=CC=CC([N+]([O-])=O)=C1NC(OC(C)(C)C)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0384465 | ETHYL-2-TERT-BUTOXY-2-CARBOXYLAMINO-3-NITROBENZOATE 95.00% | 136285-65-9 | 5MG | $498.32 | 2021-12-16 | Buy |
| Ambeed | A884767 | Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | 136285-65-9 | 100g | $578 | 2021-12-16 | Buy |
| Ambeed | A884767 | Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | 136285-65-9 | 500g | $2125 | 2021-12-16 | Buy |
| Ambeed | A884767 | Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | 136285-65-9 | 1g | $26 | 2021-12-16 | Buy |
| Ambeed | A884767 | Ethyl2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate 95+% | 136285-65-9 | 5g | $87 | 2021-12-16 | Buy |
Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate Chemical Properties,Uses,Production
Uses
This product is an intermediate of candesartan cilexetil. It is used as a standard reference in biochemical studies for content determination, identification, pharmacological experiments, activity screening, etc.
Acquired resistance
A mixture of ethyl 2-carboxy-3-nitrobenzoate(23.9 g) and thionyl chloride (12 ml) in benzene (150 ml) was heated under reflux for 3 hours. The reaction mixture was concentrated to dryness. The resultant acid chloride (26 g, quantitative) was dissolved in methylene chloride (20 ml). The solution was added dropwise to a mixture of sodium azide (9.75 g) in dimethylformamide(DMF) (20 ml) while stirring vigorously. The reaction mixture was poured into ether-hexane (3:1, 200 ml) and water (250 ml) to separate into two layers. The organic layer was washed with water and then dried, followed by evaporation of the solvent. The residue was dissolved in t-butanol (200 ml), and the solution was heated gradually with stirring, followed by heating under reflux for 2 hours. The reaction mixture was concentrated in vacuo to give an oily product Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate (30 g).
Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate Preparation Products And Raw materials
Global( 138)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 967 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8792 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15079 | 58 |
| Yangzhou Model Electronic Materials Co., Ltd. | +8613761402923 | sales@modeltemol.com | CHINA | 571 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-12 | Azilsartan impurity Z | US $0.00-0.00 / mg | 10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
 |
2026-03-12 | Candesartan Impurity 16
136285-65-9
|
US $0.00-0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
![2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester pictures](/ProductImageEN/2023-03/Small/b9bad03d-e7c0-44b4-9ef3-887e80ed4f98.png) |
2026-02-25 | 2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester
136285-65-9
|
US $200.00-170.00 / kg | 100kg | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD |
-
- Azilsartan impurity Z
- US $0.00-0.00 / mg
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- Candesartan Impurity 16
136285-65-9
- US $0.00-0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- 2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester
136285-65-9
- US $200.00-170.00 / kg
- 99.99%
- Hebei Dangtong Import and export Co LTD
136285-65-9(Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate)Related Search:
Trityl candesartan cilexetil
Candesartan cilexetil
Trityl candesartan
Candesartan
Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate
2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester
BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER
Methyl 2-ethoxybenzimidazole-7-carboxylate
Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) methyl]
BENZOIC ACID, 2-[[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]AMINO]-3-NITRO-METHYL ESTER
1of3
2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-nitrobenzoic acid ethyl ester
Ethyl-2-(tertiary butoxy carbonyl aMino)-3-nitro benzoate
2-[1.1-diMethyl ethyl ethoxy carbonyl]aMino-3-nitro benzoic acid Ethyl Ester ( C3 )
Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
Ethyl 2-[(t-butoxycarbonyl)amino]-3-nitrobenzoate
Candesartan ester intermediate C3
Benzoicacid, 2-[[(1, 1-diMethylethoxy)carbonyl]aMino]-3-nitro-, ethyl ester
Ethyl 2-((((2-methylpentan-2-yl)oxy)carbonyl)amino)-3-nitrobenzoate
2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester
Azilsartan impurity Z
ETHYL-2-T-BUTOXY-2-CARBOXYLAMINO-3-NITROBENZOATE 136285-65-9
2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
Ethyl 2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-nitrobenzoate
Azilsartan Impurity 113
Nicotinamide Impurity 62
Candesartan Impurity 16
Azilsartan Impurity C2 (2-N-(t-Butoxycarboxyl)amino-3-nitrobenzoate ethyl ester)
136285-65-9
