RalfinaMide Mesylate
- CAS No.
- 202825-45-4
- Chemical Name:
- RalfinaMide Mesylate
- Synonyms
- CS-1138;RALFINAMIDE MESYLATE;FCE-26742A (mesylate);Ralfinamide mesylate, 10 mM in DMSO;(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)aMino)propanaMide Methanesulfonate;(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonic acid;(2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate;FCE-26742A,Na channels,Na+ channels,Ralfinamide mesylate,Sodium Channel,Ralfinamide,inhibit,Inhibitor
- CBNumber:
- CB32538283
- Molecular Formula:
- C18H23FN2O5S
- Molecular Weight:
- 398.4490232
- MDL Number:
- MFCD19690932
- MOL File:
- 202825-45-4.mol
- MSDS File:
- SDS
RalfinaMide Mesylate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0378 | Ralfinamide mesylate ≥98% (HPLC) | 202825-45-4 | 10mg | $129 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0378 | Ralfinamide mesylate ≥98% (HPLC) | 202825-45-4 | 50mg | $404 | 2024-03-01 | Buy |
| Tocris | 4029 | Ralfinamide mesylate ≥99%(HPLC) | 202825-45-4 | 10 | $136 | 2021-12-16 | Buy |
| Tocris | 4029 | Ralfinamide mesylate ≥99%(HPLC) | 202825-45-4 | 50 | $572 | 2021-12-16 | Buy |
| TRC | R075000 | Ralfinamide mesylate | 202825-45-4 | 250mg | $1190 | 2021-12-16 | Buy |
RalfinaMide Mesylate Chemical Properties,Uses,Production
Uses
Ralfinamide mesylate is a mixed sodium and N-type calcium channel protein inhibitor. Inhibitory activity of Ralfinamide mesylate is voltage dependent, with higher potency towards inactivated channels. Ralfinamide mesylate is useful in preventing, alleviating and curing a wide range of pathologies, including pain, migraine, peripheral diseases, cardiovascular diseases, inflammatory processes affecting all body systems, disorders affecting skin and related tissues, disorders of the respiratory system, disorders of the immune and endocrinol. systems, gastrointestinal, urogenital, metabolic and seizure disorders.
Biological Activity
Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.
in vivo
Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain[1].
| Animal Model: | 81 adult male Sprague–Dawley male rats (260–460 g)[1] |
| Dosage: | 80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative) |
| Administration: | Oral gavage; twice daily; until postoperative day 42 |
| Result: | Suppressed neuropathic pain. |
RalfinaMide Mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29807 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jk.info@jkchemical.com | China | 96815 | 76 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 997 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 25003 | 65 |
View Lastest Price from RalfinaMide Mesylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-28 | Ralfinamide mesylate
202825-45-4
|
US $71.00-270.00 / mg | 99.83% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-14 | RalfinaMide Mesylate
202825-45-4
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
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- Ralfinamide mesylate
202825-45-4
- US $71.00-270.00 / mg
- 99.83%
- TargetMol Chemicals Inc.
-
- RalfinaMide Mesylate
202825-45-4
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co