ChemicalBook >> CAS DataBase List >>(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

CAS No.
380499-07-0
Chemical Name:
(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine
Synonyms
Desfluro Aprepitant;Aprepitant Impurity 6;Aprepitant Impurity 69;Aprepitant dehydro dealkyl;(R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine;(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine;2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-;(R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (Aprepitant Impurity)
CBNumber:
CB32542880
Molecular Formula:
C20H16F7NO2
Molecular Weight:
435.34
MDL Number:
MOL File:
380499-07-0.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
Product description Number Pack Size Price
(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine B657140 1mg $155
(2R)-2-[(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY]-3-(4-FLUOROPHENYL)-5,6-DIHYDRO-2H-1,4-OXAZINE 95.00% APN0002125 5MG $502.61

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Properties

solubility Chloroform, Ethyl Acetate
form Solid
color Off-White
FDA UNII 38EA8GN2BN

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B657140 (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine 380499-07-0 1mg $155 2021-12-16 Buy
American Custom Chemicals Corporation APN0002125 (2R)-2-[(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY]-3-(4-FLUOROPHENYL)-5,6-DIHYDRO-2H-1,4-OXAZINE 95.00% 380499-07-0 5MG $502.61 2021-12-16 Buy
Product number Packaging Price Buy
B657140 1mg $155 Buy
APN0002125 5MG $502.61 Buy

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of enantiomerically pure Aprepitant diastereomers and derivatives.

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Preparation Products And Raw materials

Raw materials

Preparation Products

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Suppliers

Global( 35)Suppliers
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Moxin Chemicals
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Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4876 55
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Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9629 60
(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Aprepitant dehydro dealkyl Desfluro Aprepitant 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)- (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine Aprepitant Impurity 6 (R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (Aprepitant Impurity) Aprepitant Impurity 69 380499-07-0 C20H16F7NO2 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals