ChemicalBook >> CAS DataBase List >>L-Octahydroindole-2-carboxylic acid
L-Octahydroindole-2-carboxylic acid
- CAS No.
- 80875-98-5
- Chemical Name:
- L-Octahydroindole-2-carboxylic acid
- Synonyms
- (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid;(2S,3aS,7aS)-Octahydro-2-indolecarboxylicacid;(2S,3αS,7αS)-Octahydro-1H-indole-2-carboxylic acid;(2R,3aR,7aR)-octahydro-1H-indole-2-carboxylic acid;L-Oic-OH;Perindopril Related Compound 7;OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID;L-(2S,3aS,7aS)-Octahydroindole-2-carboxylic Acid;1H-Indole-2-carboxylicacid,octahydro-,(2S,3aS,7aS)-(9CI);Compound 80875-98-5
- CBNumber:
- CB3258000
- Molecular Formula:
- C9H15NO2
- Molecular Weight:
- 169.22
- MDL Number:
- MFCD07782125
- MOL File:
- 80875-98-5.mol
Last updated:2026-02-02 18:10:39
| Product description | Number | Pack Size | Price |
| Perindopril impurity A European Pharmacopoeia (EP) Reference Standard | Y0000237 | 15 mg | $156 |
| Perindopril Related Compound A pharmaceutical secondary standard, certified reference material | PHR3078 | 50MG | $592 |
| Perindopril impurity A European Pharmacopoeia (EP) Reference Standard | Y0000237 | y0000237 | $153 |
| Perindopril Related Compound A United States Pharmacopeia (USP) Reference Standard | 1510890 | 0 | $0 |
| (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic Acid >98.0%(GC)(T) | O0370 | 1g | $49 |
| More product size | |||
| Melting point | 275-277°C |
|---|---|
| Boiling point | 318.6±25.0 °C(Predicted) |
| Density | 1.135±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Methanol (Sparingly), Water (Slightly) |
| pka | 2.47±0.20(Predicted) |
| color | White to Off-White |
| PH | -50 (c=1 in methanol) |
| Water Solubility | Soluble in methanol and water. |
| Major Application | pharmaceutical |
| InChI | InChI=1S/C9H15NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h6-8,10H,1-5H2,(H,11,12)/t6-,7-,8-/m0/s1 |
| InChIKey | CQYBNXGHMBNGCG-FXQIFTODSA-N |
| SMILES | N1[C@]2([H])[C@@]([H])(CCCC2)C[C@H]1C(O)=O |
| LogP | 0.3 at 25℃ and pH5 |
| CAS DataBase Reference | 80875-98-5(CAS DataBase Reference) |
| FDA UNII | 9ID44U804I |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
L-Octahydroindole-2-carboxylic acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000237 | Perindopril impurity A European Pharmacopoeia (EP) Reference Standard | 80875-98-5 | 15 mg | $156 | 2025-07-31 | Buy |
| Sigma-Aldrich | PHR3078 | Perindopril Related Compound A pharmaceutical secondary standard, certified reference material | 80875-98-5 | 50MG | $592 | 2025-07-31 | Buy |
| Sigma-Aldrich | Y0000237 | Perindopril impurity A European Pharmacopoeia (EP) Reference Standard | 80875-98-5 | y0000237 | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1510890 | Perindopril Related Compound A United States Pharmacopeia (USP) Reference Standard | 80875-98-5 | 0 | $0 | 2021-12-16 | Buy |
| TCI Chemical | O0370 | (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic Acid >98.0%(GC)(T) | 80875-98-5 | 1g | $49 | 2025-07-31 | Buy |
L-Octahydroindole-2-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
An intermediate in the synthesis of Perindopril. Perindopril USP Related Compound A.
Synthesis
539820-41-2
80875-98-5
General procedure for the synthesis of L-octahydroindole-2-carboxylic acid from the compound (CAS: 539820-41-2): 200 g of the compound obtained in the previous step was dissolved in acetic acid, followed by the addition of 5 g of 10% Pt/C catalyst to the hydrogenator. The hydrogenation reaction was carried out at room temperature and 5 bar hydrogen pressure until a theoretical amount of hydrogen was absorbed. Upon completion of the reaction, the catalyst was removed by filtration and the resulting solid product was collected by filtration after the reaction solution was cooled to 0 to 5 °C. The reaction was carried out at room temperature and 5 bar hydrogen pressure. The filter cake was washed with a suitable solvent and dried under constant weight conditions. The final product was (2S,3aS,7aS)-octahydroindole-2-carboxylic acid in 87% yield and 99% enantiomeric purity.
References
[1] Patent: US2006/167273, 2006, A1. Location in patent: Page/Page column 2
L-Octahydroindole-2-carboxylic acid Preparation Products And Raw materials
Global( 510)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5241 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20126 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13798 | 58 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21595 | 55 |
View Lastest Price from L-Octahydroindole-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-03 | L-Octahydroindole-2-carboxylic acid
80875-98-5
|
US $0.00 / kg | 1kg | 98% | 100kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-02-28 | L-Octahydroindole-2-carboxylic acid
80875-98-5
|
US $793.00 / KG | 1KG | 99% | 10000KG | Baoji Guokang Healthchem Co., Ltd. | |
 |
2026-02-02 | (2S,3AS,7aS)-Octahydroindole-2-carboxylic acid
80875-98-5
|
US $29.00 / mg | ≥98% | 10g | TargetMol Chemicals Inc. |
-
- L-Octahydroindole-2-carboxylic acid
80875-98-5
- US $0.00 / kg
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- L-Octahydroindole-2-carboxylic acid
80875-98-5
- US $793.00 / KG
- 99%
- Baoji Guokang Healthchem Co., Ltd.
-
- (2S,3AS,7aS)-Octahydroindole-2-carboxylic acid
80875-98-5
- US $29.00 / mg
- ≥98%
- TargetMol Chemicals Inc.
80875-98-5(L-Octahydroindole-2-carboxylic acid)Related Search:
OCTAHYDRO-INDOLE-2-CARBOXYLIC ACID
(2S,3αS,7αS)-Octahydro-1H-indole-2-carboxylic acid
[2S-(2a,3ab,7ab)]-Octahydro-1H-indole-2-carboxylic Acid
L-(2S,3aS,7aS)-Octahydroindole-2-carboxylic Acid
(2s,3as,7as)-Octahydro-1h-Indo
1H-Indole-2-carboxylicacid,octahydro-,(2S,3aS,7aS)-(9CI)
(2S,3aS,7aS)-2-Carboxyperhydroindole
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
L-2-carboxyoctahydroindole
(2S,3aS,7aS)-1-Octahydro-1H-indole-2-car
(2S,3aS,7aS)-Octahydro-2-indolecarboxylicacid
(2s，3as，7as)-octabyche-lh-indole-2-carboxylicacid
L-Octahydroindole-2-carboxylic acid≥ 98% (HPLC)
L-Oic-OH
2S,3AS,7AS)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID(RE-EXP/IMPTD VDE BE N.9512629/9.6.15 P.NO.V/30/02/15/MISC/1 D.29.11.15
Perindopril Impurity 1(Perindopril EP Impurity A )
(2S,3As,7As)Octahydro-1H Indole-2-Carboxylic Acid (Ohi Acid)
(2S,3AS,7AS)-2-Carboxyoctahydroindole octahydro-1H-indole-2-carboxylic acid
Perindopril related compounds 7
[2S-(2a,3a,7a)]-Octahydro-1H-indole-2-carboxylic Acid
L-Octahydroindole-2-carboxylic acid ,98%
(2S,3aS,7aS)-2,3,3aβ,4,5,6,7,7aβ-Octahydro-1H-indole-2α-carboxylic acid
[2S,3aβ,7aβ,(-)]-Octahydro-1H-indole-2α-carboxylic acid
(2S,3aR,7aR)-2,3,3aα,4,5,6,7,7aα-Octahydro-1H-indole-2α-carboxylic acid
(2S,3aS,7As)-Octanhydro-1H-Indole-2-Carboxylic Acid
L-Octahydroindole-2-
Perindopril Intermediate 3
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
(InterMediates for Perindopril)
[2S-(2α,3aβ,7aβ)]-Octahydro-1H-indole-2-carboxylic Acid
H-Oic-OH, (2S,3aS,7aS)-1-Octahydro-1H-indole-2-carboxylic acid
1H-Indole-2-carboxylicacid, octahydro-, (2S,3aS,7aS)-
(2S,3aS,7aS)-OCLahydroindole-2-Carboxylic Acid
(2α,3aβ,7aβ)-octahydro-1H-indole-2-carboxylic acid
Perindopril EP IMpurity-A (USP RC A)
Perindopril EP IMpurity A
Perindopril Related CoMpound A
(2S,3aS,7aS)-Octahydroindole-2-carboxylicacid,98%
perindopril impurity
(S)-Octahydroindole-2-carboxylic acid
Ramipril Bicyclic Acid
Perindopril Related Compound 7
(2R,3aR,7aR)-octahydro-1H-indole-2-carboxylic acid
Perindopril tert-Butylamine Impurity Ⅰ:L-(2S,3aS,7aS)-Octahydroindole-2-carboxylic Acid
(2S,3aS,7aS)-Octahydro-1H-indole-2-
Perindopril impurity A CRS
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylicAcid>
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid(PER-6)
L-octahydroindole dicarboxylic acid
Perindopril EP Impurity A/Perindopril USP RC- A
Perindopril EP Impurity A (Ramipril Bicyclic Acid)
Ramipril Bicyclic Acid (Perindopril EP Impurity A)
Perindopril Related Compound A ((2S,3aS,7aS)-octahydro-1H-indole-2-carboxylic acid) (1510890)
perindopril impurity Ⅰ
〔 (2S,3aS,7aS)-octahydro-1H-i ndole-2-carboxylic acid〕
L-Octahydroindole-2-carboxylic
(2S,3αS,7αS)-Octahydro-1H-indole-2-carboxylicacid
Perindopril tert-Butylamine Impurity A
Perindopril tert-Butylamine EP Impurity A
Perindopril USP Related Compound A
