N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine
- CAS No.
- 1353979-43-7
- Chemical Name:
- N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine
- Synonyms
- Compound8(C8);TRPM4 inhibitor 8;Brophenexin (free base);NMDAR/TRPM4 inhibitor 8;NMDAR/TRPM4-IN-2 (free base);TRPM4 inhibitor 8, 10 mM in DMSO;NMDAR/TRPM4 inhibitor 8 (Compound 8);(2-aminoethyl)[(3-bromophenyl)methyl]ethylamine;N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine;N'-[(3-bromophenyl)methyl]-N'-ethylethane-1,2-diamine
- CBNumber:
- CB32581603
- Molecular Formula:
- C11H17BrN2
- Molecular Weight:
- 257.17
- MDL Number:
- MOL File:
- 1353979-43-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H335-H314 |
| Precautionary statements | P260-P264-P270-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501 |
N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | DEC97943 | NMDAR/trpm4 inhibitor 8 | 1353979-43-7 | 250mg | $350 | 2026-06-04 | Buy |
| Biosynth | DEC97943 | NMDAR/trpm4 inhibitor 8 | 1353979-43-7 | 2.5g | $1180 | 2026-06-04 | Buy |
| ChemScene | CS-0181723 | Brophenexin (free base) ≥97% | 1353979-43-7 | 100mg | $125 | 2026-06-04 | Buy |
| ChemScene | CS-0181723 | Brophenexin (free base) ≥97% | 1353979-43-7 | 250mg | $164 | 2026-06-04 | Buy |
| ChemScene | CS-0181723 | Brophenexin (free base) ≥97% | 1353979-43-7 | 1g | $331 | 2026-06-04 | Buy |
N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine Chemical Properties, Uses, Production
Uses
Brophenexin free base (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. Brophenexin free base shows neuroprotective activity. Brophenexin free base prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. Brophenexin free base protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss[1].
IC 50
NMDA Receptor
References
[1] Yan J, et al. Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants. Science. 2020 Oct 9;370(6513):eaay3302. DOI:10.1126/science.aay3302
N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine Preparation Products And Raw materials
Raw materials
Preparation Products
N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amber MolTech LLC | 086-010-62176588 | amber@jyamber.com | China | 10150 | 56 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 13301690235 | Sales@ATKchemical.com | China | 9711 | 58 |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 3983243027@qq.com | China | 9974 | 58 |
| Shanghai Thunder Biological Technology Co., Ltd. | 18621609968 | 1162686636@qq.com | China | 1032 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| DC Chemicals | 021-58447131 13564518121 | doncunbiosci@gmail.com | China | 618 | 58 |
View Latest Price from N*1*-(3-BroMo-benzyl)-N*1*-ethyl-ethane-1,2-diaMine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-07-18 | TRPM4 inhibitor 8
1353979-43-7
|
$35.00-113.00 | 99.84% | 10g | TargetMol Chemicals Inc. |
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- TRPM4 inhibitor 8
1353979-43-7
- $35.00-113.00
- 99.84%
- TargetMol Chemicals Inc.






