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Tubastatin A hydrochloride

Tubastatin A hydrochloride structure

CAS No.: 1310693-92-5

Chemical Name:: Tubastatin A hydrochloride

Synonyms: TSA HCl;CS-1894;Tubastatin A HCl salt;Tubastatin A HCl, >=98%;Tubastatin A hydrochloride;TUBASTATIN A HYDROCHLORIDE;TSA HCL;Tubastatin A HCl (AG-CR-13900, TubA);Tubastatin A Hydrochloride, 10 mM in DMSO;Tubastatin A hydrochloride (Tubastatin A HCl;Tubastatin A hydrochloride ISO 9001：2015 REACH

CBNumber:: CB32589694

Molecular Formula:: C20H22ClN3O2

Molecular Weight:: 371.87

MDL Number:: MFCD20488052

MOL File:: 1310693-92-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-03 11:24:09

Product description	Number	Pack Size	Price
Tubastatin A hydrochloride ≥98% (HPLC)	SML0044	5mg	$232
Tubastatin A hydrochloride ≥98% (HPLC)	SML0044	25mg	$887
Tubastatin A Hydrochloride	T3687	25MG	$190
Tubastatin A Hydrochloride	T3687	100MG	$580
Tubastatin A Hydrochloride	167001	10mg	$382
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Tubastatin A hydrochloride Properties

Melting point	>221°C (subl.)
storage temp.	-20°C
solubility	Soluble in DMSO or Water.
form	powder
color	white to tan
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChI	InChI=1S/C20H21N3O2.ClH/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25;/h2-9,25H,10-13H2,1H3,(H,21,24);1H
InChIKey	LJTSJTWIMOGKRJ-UHFFFAOYSA-N
SMILES	C(C1C=CC(C(=O)NO)=CC=1)N1C2=CC=CC=C2C2CN(C)CCC1=2.Cl
FDA UNII	UHCM2AYJVX
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
WGK Germany	3
HS Code	29339900
Storage Class	11 - Combustible Solids

Tubastatin A hydrochloride price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0044	Tubastatin A hydrochloride ≥98% (HPLC)	1310693-92-5	5mg	$232	2026-04-30	Buy
Sigma-Aldrich	SML0044	Tubastatin A hydrochloride ≥98% (HPLC)	1310693-92-5	25mg	$887	2026-04-30	Buy
TCI Chemical	T3687	Tubastatin A Hydrochloride	1310693-92-5	25MG	$190	2024-03-01	Buy
TCI Chemical	T3687	Tubastatin A Hydrochloride	1310693-92-5	100MG	$580	2024-03-01	Buy
Usbiological	167001	Tubastatin A Hydrochloride	1310693-92-5	10mg	$382	2026-06-03	Buy

Product number	Packaging	Price	Buy
SML0044	5mg	$232	Buy
SML0044	25mg	$887	Buy
T3687	25MG	$190	Buy
T3687	100MG	$580	Buy
167001	10mg	$382	Buy

Tubastatin A hydrochloride Chemical Properties,Uses,Production

Description

Tubastatin A (1310693-92-5) is a potent and highly selective inhibitor of HDAC6 (IC50= 15 nM, >1000-fold selectivity against other HDAC isoforms, approx. 60-fold versus HDAC8).1It displayed anti-inflammatory and anti-rheumatic effects in Freund’s competitive adjuvant induced animal model of inflammation.2Tubastatin A inhibited TNF-α (IC50= 272 nM) and IL-6 (IC50 = 712 nM) in LPS stimulated human THP-1 macrophages.2Tubastatin A has also been shown to have therapeutic potential for treatment of Alzheimer’s disease via altered amyloid-β load and reduced tau hyperphosphorylation.3-5

Uses

Tubastatin A Hydrochloride is a neuroprotective HDAC6 inhibitor and is also known to induce hyperacetylation in primary cortical neuron cultures.

Uses

Tubastatin A Hydrochloride is an LSD1 inhibitor, which targets SOX2-expressing cancer cells.

Biochem/physiol Actions

Tubastatin A increases the total numbers of mitochondria and restores the number of moving mitochondria in DRG neurons. It reverses the axonal loss in peripheral neurons in mouse model of Charcot-Marie-Tooth disease. Tubastatin A inhibits the deacetylation of α-tubulin in murine myoblasts.

target

HDAC6

storage

Store at -20°C

References

[1] KYLE V. BUTLER. Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A[J]. Journal of the American Chemical Society, 2010, 132 31: 10842-10846. DOI:10.1021/ja102758v
[2] SANTOSH VISHWAKARMA . Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects[J]. International immunopharmacology, 2013, 16 1: Pages 72-78. DOI:10.1016/j.intimp.2013.03.016
[3] MONIKA NOACK Christiane R L Janina Leyk. HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes[J]. Glia, 2014, 62 4: 535-547. DOI:10.1002/glia.22624
[4] MAJ-LINDA SELENICA. Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.[J]. Alzheimer’s Research & Therapy, 2014, 6 1: 12. DOI:10.1186/alzrt241
[5] LING ZHANG. Tubastatin A/ACY-1215 improves cognition in Alzheimer’s disease transgenic mice.[J]. ACS Applied Electronic Materials, 2014: 1193-1205. DOI:10.3233/jad-140066

Tubastatin A hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Tubastatin A hydrochloride Suppliers

Global( 155)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20582	58
Chemia Biotechnology（Shanghai） Co., Ltd	+8613816753574	info@chemia-pharm.com	CHINA	311	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58
Chemia Biotechnology（Shanghai） Co., Ltd	58
Zhejiang J&C Biological Technology Co.,Limited	58

View Lastest Price from Tubastatin A hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-02	Tubastatin A Hydrochloride 1310693-92-5	$45.00-77.00		97.78%	10g	TargetMol Chemicals Inc.
2025-11-18	Tubastatin A hydrochloride 1310693-92-5	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2019-12-23	Tubastatin A HCl 1310693-92-5	$1.00	1g	Min98% HPLC		Career Henan Chemical Co

Tubastatin A Hydrochloride
1310693-92-5
$45.00-77.00
97.78%
TargetMol Chemicals Inc.

Tubastatin A hydrochloride
1310693-92-5
$1.10
99.00%
Dideu Industries Group Limited

Tubastatin A HCl
1310693-92-5
$1.00
Min98% HPLC
Career Henan Chemical Co

Tubastatin A hydrochloride Spectrum

Tubastatin A hydrochloride(1310693-92-5)MS Tubastatin A hydrochloride(1310693-92-5)¹HNMR

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N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A hydrochloride TSA HCl Tubastatin A Hydrochloride (Also See: T897000) Tubastatin A HCl salt N-hydroxy-4-((2-methyl-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)methyl)benzamide hydrochloride N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl Tubastatin A hydrochloride N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride N-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]-indol-5(2H)-yl)methyl)benzamide hydrochloride N-Hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzamide hydrochloried Tubastatin A HCl, >=98% Tubastatin A HCl, 98%, a potent and selective HDAC6 inhibitor TUBASTATIN A HYDROCHLORIDE;TSA HCL CS-1894 N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5 -yl)methyl]benzamide hydrochloride (1:1) Tubastatin A hydrochloride ISO 9001：2015 REACH Tubastatin A HCl (AG-CR-13900, TubA) N-Hydroxy-4-((2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl)benzamide hydrochloride N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-, hydrochloride (1:1) Tubastatin A Hydrochloride, 10 mM in DMSO Tubastatin A hydrochloride (Tubastatin A HCl 1310693-92-5 C20H21N3O2HCl Inhibitors