4-BroMo-2-Methylbutan-2-ol
- CAS No.
- 35979-69-2
- Chemical Name:
- 4-BroMo-2-Methylbutan-2-ol
- Synonyms
- 4-BroMo-2-Methyl-2-butanol;4-BroMo-2-Methylbutan-2-ol;2-Butanol, 4-broMo-2-Methyl-;4-BroMo-2-hydroxy-2-Methylbutane;4-bromo-2-methyl-butan-2-ol - [B70111];4-BroMo-2-Methylbutan-2-ol ISO 9001：2015 REACH
- CBNumber:
- CB32619955
- Molecular Formula:
- C5H11BrO
- Molecular Weight:
- 167.04
- MDL Number:
- MFCD20483824
- MOL File:
- 35979-69-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Bromo-2-methyl-2-butanol | B685265 | 1g | $1110 |
| 4-Bromo-2-methylbutan-2-ol 95% | 143927 | 5g | $1592 |
| 4-Bromo-2-methylbutan-2-ol 95% | OR939949 | 1g | $573 |
| 4-Bromo-2-methylbutan-2-ol 95% | 143927 | 1g | $589 |
| 4-Bromo-2-methylbutan-2-ol 95+% | 35424 | 1g | $890 |
| More product size | |||
| Boiling point | 189.7±23.0 °C(Predicted) |
|---|---|
| Density | 1.371±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| pka | 14.79±0.29(Predicted) |
| color | Brown |
| InChI | InChI=1S/C5H11BrO/c1-5(2,7)3-4-6/h7H,3-4H2,1-2H3 |
| InChIKey | RBFVGQWGOARJRU-UHFFFAOYSA-N |
| SMILES | CC(C)(O)CCBr |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2905599890 |
4-BroMo-2-Methylbutan-2-ol price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B685265 | 4-Bromo-2-methyl-2-butanol | 35979-69-2 | 1g | $1110 | 2021-12-16 | Buy |
| Matrix Scientific | 143927 | 4-Bromo-2-methylbutan-2-ol 95% | 35979-69-2 | 5g | $1592 | 2021-12-16 | Buy |
| Apolloscientific | OR939949 | 4-Bromo-2-methylbutan-2-ol 95% | 35979-69-2 | 1g | $573 | 2021-12-16 | Buy |
| Matrix Scientific | 143927 | 4-Bromo-2-methylbutan-2-ol 95% | 35979-69-2 | 1g | $589 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 35424 | 4-Bromo-2-methylbutan-2-ol 95+% | 35979-69-2 | 1g | $890 | 2021-12-16 | Buy |
4-BroMo-2-Methylbutan-2-ol Chemical Properties,Uses,Production
Chemical Properties
4-BroMo-2-Methylbutan-2-ol is Brown Oil
Uses
4-Bromo-2-methyl-2-butanol is a brominated tertiary alcohol used as a reagent in the preparation of vitamin D3 analogues.
Synthesis
539-74-2
75-16-1
35979-69-2
General procedure for the synthesis of 4-bromo-2-methyl-2-butanol from ethyl 3-bromopropionate and methylmagnesium bromide: To a solution of ethyl 3-bromopropionate (0.2 g, 1.2 mmol) in tetrahydrofuran (THF, 5 mL) was slowly added methylmagnesium bromide (2.4 mL, 2.4 mmol) at 0°C. The reaction mixture was stirred continuously until a thin layer chromatography (TLC) analysis showed complete consumption of the raw material. The reaction mixture was stirred continuously at 0°C until thin layer chromatography (TLC) analysis showed complete consumption of the raw material [Unfolding agent: petroleum ether/ethyl acetate (3:1), Rf value of the product was 0.3]. Upon completion of the reaction, the reaction was quenched with aqueous ammonium chloride (2 mL) at 0°C. The reaction mixture was extracted with ethyl acetate and water by partitioning. The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated to give the crude product. The crude product was purified by column chromatography using petroleum ether/ethyl acetate (3:1) as eluent to give 4-bromo-2-methyl-2-butanol (0.15 g, 75.1% yield) as a yellow oil.
References
[1] Patent: WO2014/143799, 2014, A2. Location in patent: Page/Page column 403
[2] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 2, p. 525 - 535
[3] Journal of Organometallic Chemistry, 1973, vol. 47, p. 337 - 350
[4] Tetrahedron Letters, 1992, vol. 33, # 1, p. 105 - 108
[5] ACS Medicinal Chemistry Letters, 2012, vol. 3, # 10, p. 828 - 833
4-BroMo-2-Methylbutan-2-ol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39020 | 58 |
View Lastest Price from 4-BroMo-2-Methylbutan-2-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 4-BroMo-2-Methylbutan-2-ol
35979-69-2
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-04-04 | 4-BroMo-2-Methylbutan-2-ol
35979-69-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2020-01-10 | 4-Bromo-2-methylbutan-2-ol
35979-69-2
|
US $1.00 / KG | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 4-BroMo-2-Methylbutan-2-ol
35979-69-2
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 4-BroMo-2-Methylbutan-2-ol
35979-69-2
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-Bromo-2-methylbutan-2-ol
35979-69-2
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
