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ChemicalBook >> CAS DataBase List >>8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Structure
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine structure
CAS No.
298220-99-2
Chemical Name:
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms
11-Fluoro Desloratadine;11-Fluoro Desloratadine HCl;Desloratadine EP Impurity A;11-Fluoro Dihydrodesloratadine;Desloratadine Impurity 1/Desloratadine EP Impurity A;Desloratadine EP Impurity A（11-Fluoro Desloratadine）;Desloratadine EP Impurity A Desloratadine EP Impurity A;Desloratadine Impurity 1 (Desloratadine EP Impurity A Monomer);8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine;8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
CBNumber:
CB32622191
Molecular Formula:
C19H20ClFN2
Molecular Weight:
330.83
MDL Number:
MFCD24386416
MOL File:
298220-99-2.mol
Last updated:2025-07-04 15:08:53
Product description Number Pack Size Price
11-FluoroDesloratadine F590900 10mg $1390
11-Fluoro desloratadine IF46257 25mg $5625
More product size
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8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Properties

Melting point >192°C (dec.)
Boiling point 426.9±45.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.16±0.10(Predicted)
form Solid
color Off-White to Pale Orange
InChI InChI=1S/C19H20ClFN2/c20-16-5-6-17-14(12-16)4-3-13-2-1-9-23-18(13)19(17,21)15-7-10-22-11-8-15/h1-2,5-6,9,12,15,22H,3-4,7-8,10-11H2
InChIKey UTRNCHWURQHTSN-UHFFFAOYSA-N
SMILES C12C(F)(C3CCNCC3)C3=CC=C(Cl)C=C3CCC1=CC=CN=2
FDA UNII O3HON4ESD6

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F590900 11-FluoroDesloratadine 298220-99-2 10mg $1390 2021-12-16 Buy
Biosynth Carbosynth IF46257 11-Fluoro desloratadine 298220-99-2 25mg $5625 2021-12-16 Buy
Product number Packaging Price Buy
F590900 10mg $1390 Buy
IF46257 25mg $5625 Buy

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Chemical Properties,Uses,Production

Uses

11-Fluoro Desloratadine is a fluorine substituted benzocycloheptapyridine derivative with antihistaminic activity.

Uses

11-Fluoro Desloratadine (Desloratadine EP Impurity A) is a fluorine substituted benzocycloheptapyridine derivative with antihistaminic activity.

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
Moxin Chemicals 		+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10237 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12373 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11922 58
R&D Scientific Inc. 		+1-2266000236 sales@rdscientific.com Canada 1899 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
QUALITY CONTROL SOLUTIONS LTD. 		+86-0755-66853366 +86-13670046396 export03@qcsrm.com China 24342 58
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd 0512-66317708 13372112871 huijuan@zitrans.cn China 1282 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
Moxin Chemicals 		58
Standardpharm Co. Ltd. 		58
Hubei Ipure Biology Co., Ltd 		58
sgtlifesciences pvt ltd 		58
China National Standard Pharmaceutical Corporation Limited 		58
R&D Scientific Inc. 		58
Aladdin Scientific 		58
QUALITY CONTROL SOLUTIONS LTD. 		58
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd 58
J & K SCIENTIFIC LTD. 76

View Lastest Price from 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Desloratadine EP Impurity A pictures 2025-07-31 Desloratadine EP Impurity A
298220-99-2
 US $0.00-0.00 / mg 10mg 95%+ 100000 Moxin Chemicals
11-Fluoro desloratadine pictures 2024-04-12 11-Fluoro desloratadine
298220-99-2
 US $4500.00 / mg 1mg 98 500 Kg R&D Scientific Inc.

298220-99-2(8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine)Related Search:

Desloratadine Epoxide DESLORATADINE-D4 Desloratadine D5 Desloratadine N-Hydroxypiperidine Desloratadine IMpurity B
Desloratadine IMpurity 3 Desloratadine IMpurity 1 Desloratadine IMpurity 6 8-Dechloro-9-chloro Desloratadine Desloratadine Impurity
Desloratadine Desloratadine Pyridine N-oxide Desloratadine Citric Amide Iso Desloratadine 5,6-Dehydro-N-methyl Desloratadine
IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate 8-Deschloro-8-bromo-N-methyl Desloratadine Desloratadine N-Carboxylic Acid Methyl Ester

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11-Fluoro Desloratadine 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Desloratadine EP Impurity A 4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b]pyridin-11-yl]piperidine 8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine Desloratadine Impurity 1/Desloratadine EP Impurity A 11-Fluoro Desloratadine HCl 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)- 8-chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 11-Fluoro Dihydrodesloratadine Desloratadine Impurity 1 (Desloratadine EP Impurity A Monomer) 8-Chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Desloratadine Impurity) Desloratadine EP Impurity A Desloratadine EP Impurity A Desloratadine EP Impurity A（11-Fluoro Desloratadine） 298220-99-2 C19H20N2ClF C19H20ClFN2 Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals