EL-102
- CAS No.
- 1233948-61-2
- Chemical Name:
- EL-102
- Synonyms
- EL-102;EL-102; EL 102;EL-102, 10 mM in DMSO;Benzenesulfonamide, N-[5-(5-cyano-3-thienyl)-2-methylphenyl]-4-methoxy-;N-[5-(5-cyano-thiophen-3-yl)-2-methyl-phenyl]-4-methoxy-benzenesulfonamide
- CBNumber:
- CB32627792
- Molecular Formula:
- C19H16N2O3S2
- Molecular Weight:
- 384.47
- MDL Number:
- MOL File:
- 1233948-61-2.mol
| Product description | Number | Pack Size | Price |
| EL-102 99.07% | CS-5641 | 5mg | $336 |
| EL-102 99.07% | CS-5641 | 50mg | $1140 |
| EL-102 99.07% | CS-5641 | 100mg | $1800 |
| EL102 >98% | DC9684 | 1g | $1900 |
| EL-102 98+% | CD31004158 | 5mg | $194 |
| More product size | |||
EL-102 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-5641 | EL-102 99.07% | 1233948-61-2 | 5mg | $336 | 2021-12-16 | Buy |
| ChemScene | CS-5641 | EL-102 99.07% | 1233948-61-2 | 50mg | $1140 | 2021-12-16 | Buy |
| ChemScene | CS-5641 | EL-102 99.07% | 1233948-61-2 | 100mg | $1800 | 2021-12-16 | Buy |
| DC Chemicals | DC9684 | EL102 >98% | 1233948-61-2 | 1g | $1900 | 2021-12-16 | Buy |
| Crysdot | CD31004158 | EL-102 98+% | 1233948-61-2 | 5mg | $194 | 2021-12-16 | Buy |
EL-102 Chemical Properties,Uses,Production
Uses
EL-102 is a hypoxia-induced factor 1 (Hif1α) inhibitor. EL-102 induces apoptosis, inhibits tubulin polymerisation and shows activities against prostate cancer. EL-102 can be used for the research of cancer[1].
in vivo
EL-102 (12 and 15 mg/kg; p.o. 5-day on and 2-day off, from 13 to 37 days after tumour transplantation) potentiates effects of docetaxel in vivo[1].
| Animal Model: | Nude mice with CWR22 xenografts[1] |
| Dosage: | 12 and 15 mg/kg |
| Administration: | Oral gavage; 12 and 15 mg/kg 5-day on and 2-day off; from 13 to 37 days after tumour transplantation |
| Result: | Showed no effect on tumor growth, but enhanced the effect of docetaxel on tumor . |
References
[1] A P Toner et al. The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivoactivity against prostate cancer and circumvents MDR1 resistance. Br J Cancer, 2013 Oct 15, 109(8): 2131-2141. DOI:10.1038/bjc.2013.537
EL-102 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4689 | 55 |
