5-AMino-6-iodo-pyridine-2-carbonitrile
- CAS No.
- 1079054-78-6
- Chemical Name:
- 5-AMino-6-iodo-pyridine-2-carbonitrile
- Synonyms
- 3-Amino-6-cyano-2-methylpyridine;5-AMino-6-Methylpicolinonitrile;3-Amino-6-cyano-2-methylpyridine,95%;5-AMino-6-iodo-pyridine-2-carbonitrile;5-Amino-6-methyl-2-pyridinecarbonitrile;2-Pyridinecarbonitrile, 5-amino-6-methyl-
- CBNumber:
- CB32629453
- Molecular Formula:
- C7H7N3
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD08062828
- MOL File:
- 1079054-78-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
5-AMino-6-iodo-pyridine-2-carbonitrile price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR921514 | 5-Amino-6-methylpicolinonitrile 98% | 1079054-78-6 | 1g | $52 | 2026-06-04 | Buy |
| Activate Scientific | AS41190 | 5-Amino-6-methylpicolinonitrile 98% | 1079054-78-6 | 1g | $65 | 2026-06-04 | Buy |
| Activate Scientific | AS41190 | 5-Amino-6-methylpicolinonitrile 98% | 1079054-78-6 | 5g | $151 | 2026-06-04 | Buy |
| Activate Scientific | AS41190 | 5-Amino-6-methylpicolinonitrile 98% | 1079054-78-6 | 25g | $484 | 2026-06-04 | Buy |
| Synthonix | A16433 | 5-amino-6-methylpyridine-2-carbonitrile 97.0% | 1079054-78-6 | 250mg | $46 | 2026-05-06 | Buy |
5-AMino-6-iodo-pyridine-2-carbonitrile Chemical Properties, Uses, Production
Synthesis
557-21-1
126325-47-1
1079054-78-6
The general procedure for the synthesis of 5-amino-6-methyl-2-cyanopyridine from zinc cyanide and 2-bromo-5-amino-6-methylpyridine was as follows: first, 6-cyano-2-methyl-3-aminopyridine was prepared; 3.5 g (18.6 mmol) of 6-bromo-2-methyl-3-aminopyridine, 352 mg (0.37 mmol) of tris(benzylideneacetone)dipalladium(0) , 532 mg (0.92 mmol) of 1,1 '-bis(diphenylphosphino)ferrocene, 146 mg (2.2 mmol) of zinc powder and 1.4 g (12 mmol) of zinc cyanide were mixed in 70 ml of N,N-dimethylacetamide. The reaction mixture was stirred at 20°C for 22 hours. After completion of the reaction, the reaction mixture was diluted with 200 ml of ethyl acetate and washed with 2N ammonium chloride solution. Note: Decantation was only possible after filtering the mixture on a Celite-type filter aid. The resulting organic phase was washed with sodium chloride solution, dried with magnesium sulfate and concentrated under reduced pressure. The evaporated residue was purified by silica gel chromatography using a dichloromethane/ethyl acetate mixture (9/1; v/v) as eluent, resulting in 1.6 g of 5-amino-6-methyl-2-cyanopyridine in the form of a yellow powder (yield = 65%). The melting point was 192-196 °C.
References
[1] Patent: US2007/54955, 2007, A1. Location in patent: Page/Page column 5
[2] Patent: WO2014/139150, 2014, A1. Location in patent: Page/Page column 55
5-AMino-6-iodo-pyridine-2-carbonitrile Preparation Products And Raw materials
5-AMino-6-iodo-pyridine-2-carbonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 974 | 65 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4875 | 55 |
| Struchem Co., Ltd. | 0512-63009836 18994340901 | helen@struchem.com | China | 3968 | 60 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 8696 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Taian Jiaye Biotechnology Co.Ltd | 15318151873;13127280945 | 285424065@qq.com | China | 9961 | 55 |
