2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
- CAS No.
- 1420998-43-1
- Chemical Name:
- 2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Synonyms
- 2-methoxy-4-methylpyridine-3-boronic acidolester;2-Methoxy-4-methylpyridine-3-boronic Acid Pinacol Ester;(2-METHOXY-4-METHYLPYRIDIN-3-YL)BORONIC ACID PINACOL ESTER;2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine;Pyridine, 2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - [M82820]
- CBNumber:
- CB32664203
- Molecular Formula:
- C13H20BNO3
- Molecular Weight:
- 249.11
- MDL Number:
- MOL File:
- 1420998-43-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 304257 | 2-Methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | 1420998-43-1 | 250.00mg | $80 | 2026-05-19 | Buy |
| Matrix Scientific | 304257 | 2-Methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | 1420998-43-1 | 1.00g | $282 | 2026-05-19 | Buy |
| Matrix Scientific | 304257 | 2-Methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | 1420998-43-1 | 5.00g | $975 | 2026-05-19 | Buy |
| Synthonix | M82820 | 2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95% | 1420998-43-1 | 100mg | $73 | 2026-05-06 | Buy |
| Synthonix | M82820 | 2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95% | 1420998-43-1 | 250mg | $80 | 2026-05-06 | Buy |
2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine Chemical Properties, Uses, Production
Synthesis
717843-51-1
73183-34-3
1420998-43-1
Synthesis of intermediate Vd: Under argon protection, 3-bromo-2-methoxy-4-methylpyridine Vc (813 mg, 4.02 mmol), bis(pinacolato)diboron (1.12 g, 4.41 mmol), PdCl2(dppf)-DCM (146 mg, 0.20 mmol) and KOAc (1.18 g, 12.0 mmol) were were added to a dry sealed tube followed by dry DMF (10 mL). The reaction mixture was stirred at 100 °C for 1.5 h. After cooling to room temperature, another portion of catalyst (75 mg, 0.092 mmol) was added. The reaction tube was resealed and stirring was continued at 100 °C overnight. After completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by evaporation. The residue was dissolved in dichloromethane (DCM) and washed with water. The organic layer was separated, dried with anhydrous MgSO4, filtered and concentrated. Purification by silica gel column chromatography (eluent: cyclohexane/EtOAc, 10% to 20% gradient) afforded the intermediate Vd as a yellow oil (2.14 g, 51% yield).1H NMR (300 MHz, CDCl3) δ 8.00 (d, J = 5.3 Hz, 1H), 6.65 (d, J = 5.3 Hz, 1H), 3.89 (s 3H), 2.33 (s, 3H), 1.40 (s, 12H).
References
[1] Patent: WO2013/14170, 2013, A1. Location in patent: Page/Page column 78-80
2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methoxy-4-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
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| Henan Alfa Chemical Co., Ltd | +8618339805032 | sale03@alfachem.cn | China | 9872 | 58 |
| LEADMEDPHARM CO.,LTD | 13674959855 13674959855 | sales@synthontech.com | China | 3025 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-81154043 17391733319 | 1086@dideu.com | China | 9970 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
| PharmaBlock Sciences (Nanjing), Inc. | 4000255188 | sales_china@pharmablock.com | China | 9999 | 58 |
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