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Amt hydrochloride

CAS No.
21463-31-0
Chemical Name:
Amt hydrochloride
Synonyms
4H-1;AMT HCL;Amt hydrochloride;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE;5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE;4H-1,3-Thiazin-2-amine, 5,6-dihydro-6-methyl-, hydrochloride (1:1)
CBNumber:
CB3266443
Molecular Formula:
C5H10N2S.ClH
Molecular Weight:
166.67
MDL Number:
MFCD00792731
MOL File:
21463-31-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:58

Amt hydrochloride Properties

Melting point 146-150°C
storage temp. 0-6°C
solubility DMF: >8 mg/ml; DMSO: >16 mg/ml; Ethanol: >25 mg/ml; Water: >25 mg/ml
form A crystalline solid
color White to off-white
Water Solubility Soluble to 10 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335
Precautionary statements  P261-P264-P271-P280-P304+P340-P305+P351+P338-P312-P337+P313-P403+P233-P405-P501
HS Code  29309099
NFPA 704
0
2 0

Amt hydrochloride price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 5mg $69 2026-04-30 Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 10mg $120 2026-04-30 Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 50mg $493 2026-04-30 Buy
Cayman Chemical 81010 AMT (hydrochloride) ≥98% 21463-31-0 100mg $783 2026-04-30 Buy
Usbiological 254626 AMT hydrochloride Asreported 21463-31-0 10mg $366 2026-06-03 Buy
Product number Packaging Price Buy
81010 5mg $69 Buy
81010 10mg $120 Buy
81010 50mg $493 Buy
81010 100mg $783 Buy
254626 10mg $366 Buy

Amt hydrochloride Chemical Properties, Uses, Production

Description

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.

Chemical Properties

white to off-white powder

Uses

AMT Hydrochloride is a potent and selective inhibitors of inducible nitric oxide synthase, which may lead to therapeutic applications in the treatment of inflammatory and autoimmune diseases.

Biological Activity

Potent, selective and reversible inhibitor of iNOS (IC 50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).

storage

Desiccate at +4°C

References

[1] M NAKANE. Novel potent and selective inhibitors of inducible nitric oxide synthase.[J]. Molecular Pharmacology, 1995, 47 4: 831-834.

Amt hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 60)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Shanghai Synmedia Chemical Co., Ltd. 021-38681880 13817889927 sales@synmedia-chem.com China 249 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4859 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310 526763801@qq.com China 7983 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9962 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58

View Latest Price from Amt hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AMT hydrochloride pictures 2026-07-14 AMT hydrochloride
21463-31-0
$73.00-113.00 99.38% 10g TargetMol Chemicals Inc.
5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE AMT HCL 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL 4H-1 4H-1,3-Thiazin-2-amine, 5,6-dihydro-6-methyl-, hydrochloride (1:1) Amt hydrochloride 21463-31-0 C5H11ClN2S C5H10N2SHCl Biochemicals and Reagents BioChemical L to O Nitric Oxide Synthase (iNOS) Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme