8-chloroiMidazo[1,5-a]pyrazine
![8-chloroiMidazo[1,5-a]pyrazine Structure](CAS/20150408/GIF/56468-23-6.gif)
- CAS No.
- 56468-23-6
- Chemical Name:
- 8-chloroiMidazo[1,5-a]pyrazine
- Synonyms
- 8-chloroiMidazo[1,5-a]pyrazine;IMidazo[1,5-a]pyrazine, 8-chloro-
- CBNumber:
- CB32669738
- Molecular Formula:
- C6H4ClN3
- Molecular Weight:
- 153.57
- MDL Number:
- MFCD20040069
- MOL File:
- 56468-23-6.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
8-chloroiMidazo[1,5-a]pyrazine price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | GCA46823 | 8-chloroimidazo[1,5-a]pyrazine | 56468-23-6 | 0.5g | $330.4 | 2026-06-04 | Buy |
| Biosynth | GCA46823 | 8-chloroimidazo[1,5-a]pyrazine | 56468-23-6 | 5g | $1475 | 2026-06-04 | Buy |
| Matrix Scientific | 298550 | 8-Chloroimidazo[1,5-a]pyrazine | 56468-23-6 | 250.00mg | $65 | 2026-05-19 | Buy |
| Matrix Scientific | 298550 | 8-Chloroimidazo[1,5-a]pyrazine | 56468-23-6 | 1.00g | $174 | 2026-05-19 | Buy |
| Matrix Scientific | 298550 | 8-Chloroimidazo[1,5-a]pyrazine | 56468-23-6 | 5.00g | $702 | 2026-05-19 | Buy |
8-chloroiMidazo[1,5-a]pyrazine Chemical Properties, Uses, Production
Synthesis
940307-81-3
![8-chloroiMidazo[1,5-a]pyrazine](/CAS/20150408/GIF/56468-23-6.gif)
56468-23-6
General procedure for the synthesis of 8-chloroimidazo[1,5-a]pyrazine from N-[(3-chloropyrazin-2-yl)methyl]formamide: To a solution of acetonitrile (5 mL) of the product of step 1 (200 mg, 1.17 mmol) was added N,N-dimethylformamide (0.5 mL) and phosphorous triclosan (0.5 mL). The reaction mixture was stirred at 60°C for 30 minutes. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure to remove phosphorous trichloride. The residue was poured into water (5 mL), stirred for 20 minutes, and then extracted with ethyl acetate (5 mL x 5). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered, and concentrated under reduced pressure to afford 8-chloroimidazo[1,5-a]pyrazine (40 mg) as a yellow solid. Analyzed by liquid chromatography-mass spectrometry (LC-MS), the molecular ion peak m/z (M + H)+ was measured to be 154.1, which was consistent with the theoretical value of 154.1.
References
[1] Patent: WO2007/64993, 2007, A2. Location in patent: Page/Page column 84
[2] Patent: WO2016/106623, 2016, A1. Location in patent: Page/Page column 111
[3] Patent: WO2016/101119, 2016, A1. Location in patent: Page/Page column 102; 103
[4] Patent: CN108191871, 2018, A. Location in patent: Paragraph 0200; 0207-0209
8-chloroiMidazo[1,5-a]pyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3827 | 58 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| ShangHai Wisacheam Pharmaceutical Co., Ltd. | 13817485796 | tim@wisacheampharm.com | China | 3698 | 58 |
| Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. | 027-65388397 18164111589 | 3321478047@qq.com | China | 2002 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
