(R)-2-(methoxycarbonylamino)-2-phenylacetic acid
- CAS No.
- 50890-96-5
- Chemical Name:
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
- Synonyms
- Moc-D-Phg;Moc-D-Phg-OH;Velpatasvir Impurity 28;MOC-D-phenylglycine acid;(R)-2-(methoxycarbonylamino)-2-phenyl;(R)-2-(methoxycarbonylamino)-2-phenylaceticaci;(R)-2-(methoxycarbonylamino)-2-phenylacetic acid;(αR)-α-[(Methoxycarbonyl)amino]benzeneacetic acid;(R)-2-(Methoxycarbonylamino)-2-phenylethanoic acid;(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetic acid
- CBNumber:
- CB32681677
- Molecular Formula:
- C10H11NO4
- Molecular Weight:
- 209.2
- MDL Number:
- MFCD12796004
- MOL File:
- 50890-96-5.mol
| Melting point | 120 °C |
|---|---|
| Boiling point | 391.3±35.0 °C(Predicted) |
| Density | 1.283±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.96±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| optical activity | Consistent with structure |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M3293 | N-Methoxycarbonyl-D-phenylglycine | 50890-96-5 | 25G | $25 | 2025-07-31 | Buy |
| TCI Chemical | M3293 | N-Methoxycarbonyl-D-phenylglycine | 50890-96-5 | 100G | $68 | 2025-07-31 | Buy |
| TRC | M342968 | (R)-2-((Methoxycarbonyl)amino)-2-phenylaceticAcid | 50890-96-5 | 50mg | $175 | 2021-12-16 | Buy |
| ChemScene | CS-0036426 | (R)-2-((Methoxycarbonyl)amino)-2-phenylaceticacid >97.0% | 50890-96-5 | 100g | $56 | 2021-12-16 | Buy |
| ChemScene | CS-0036426 | (R)-2-((Methoxycarbonyl)amino)-2-phenylaceticacid >97.0% | 50890-96-5 | 500g | $167 | 2021-12-16 | Buy |
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid Chemical Properties,Uses,Production
Uses
(R)-2-((Methoxycarbonyl)amino)-2-phenylacetic acid is a Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) derivative[1].
Synthesis
875-74-1
79-22-1
50890-96-5
D-Phenylglycine (10.0 g, 66.1 mmol) and sodium hydroxide (21.2 g, 265 mmol) were dissolved in water (60 mL) at 0°C and stirred until completely dissolved. Subsequently, methyl chloroformate (10.2 mL, 133 mmol) was added slowly and dropwise over 20 minutes. The reaction mixture was continued to be stirred at 0°C for 1 hour. Upon completion of the reaction, it was acidified with concentrated hydrochloric acid (25 mL, 300 mmol) to pH < 2. The acidic aqueous phase was extracted with ethyl acetate (3 x 100 mL), the organic phases were combined and dried over anhydrous magnesium sulfate. After filtration to remove the desiccant, the organic phase was concentrated under reduced pressure to afford N-methoxycarbonyl-D-phenylglycine (Int-2a, 12.6 g, 91% yield), which could be used for subsequent reactions without further purification.
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
(R)-2-(methoxycarbonylamino)-2-phenylacetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1014 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20185 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1319 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from (R)-2-(methoxycarbonylamino)-2-phenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
50890-96-5
|
US $5.00-0.10 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-07-08 | (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
50890-96-5
|
US $0.00-0.00 / kg | 1kg | 97% | 100kg | Hangzhou ICH Biofarm Co., Ltd | |
 |
2023-05-04 | Moc-D-phenylglycine
50890-96-5
|
US $48.00-40.00 / KG | 1化验 | 99% | 2tons | Guangzhou Sunton Biotechnology Co., Ltd. |
-
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
50890-96-5
- US $5.00-0.10 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- (R)-2-(methoxycarbonylamino)-2-phenylacetic acid
50890-96-5
- US $0.00-0.00 / kg
- 97%
- Hangzhou ICH Biofarm Co., Ltd
-
- Moc-D-phenylglycine
50890-96-5
- US $48.00-40.00 / KG
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
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