9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide
- CAS No.
- 182438-98-8
- Chemical Name:
- 9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide
- Synonyms
- 9-(4-bromobutyl)-N-(2,2,2-trifluoroethyl)fluorene-9-carboxamide;9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide;9H-Fluorene-9-carboxamide, 9-(4-bromobutyl)-N-(2,2,2-trifluoroethyl)-
- CBNumber:
- CB32685099
- Molecular Formula:
- C20H19BrF3NO
- Molecular Weight:
- 426.27
- MDL Number:
- MFCD27978674
- MOL File:
- 182438-98-8.mol
| Product description | Number | Pack Size | Price |
| 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | B486358 | 1g | $265 |
| 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | 4748-B-00 | 1g | $720 |
| 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | 8202CR | 5g | $277 |
| 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide 95%+ | CM250611 | 5g | $281 |
| 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide 97% | CD00007199 | 5g | $297 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
| HS Code | 2924297099 |
9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B486358 | 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | 182438-98-8 | 1g | $265 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4748-B-00 | 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | 182438-98-8 | 1g | $720 | 2021-12-16 | Buy |
| AK Scientific | 8202CR | 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | 182438-98-8 | 5g | $277 | 2021-12-16 | Buy |
| Chemenu | CM250611 | 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide 95%+ | 182438-98-8 | 5g | $281 | 2021-12-16 | Buy |
| Crysdot | CD00007199 | 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide 97% | 182438-98-8 | 5g | $297 | 2021-12-16 | Buy |
9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide Chemical Properties,Uses,Production
Synthesis
373-88-6
182438-97-7
182438-98-8
General procedure: In a three-necked flask equipped with a thermometer and a dropping funnel, 9-(4-bromobutyl)-9H-fluorene-9-carboxylic acid (25.0 g, 73 mmol), dichloromethane (250 ml), oxalyl chloride (11.0 g, 87 mmol), and DMF (5 drops) were added, and the reaction was stirred for 2 hr. at room temperature and under nitrogen protection. After completion of the reaction, the solvent was removed by evaporation under reduced pressure. The residue was dissolved in dichloromethane (50 mL). Another 2,2,2-trifluoroethylamine hydrochloride (10.9 g, 80 mmol) and triethylamine (31 ml, 220 mmol) were dissolved in dichloromethane (100 ml), and this solution was added to the dichloromethane solution of the aforementioned residue. The reaction mixture was washed sequentially with water, 1N HCl solution, saturated aqueous NaHCO3 solution and saturated brine (200 mL each, washed 3 times), the organic phase was dried with anhydrous Na2SO4 and the solvent was removed by evaporation under reduced pressure. The residue was purified by silica gel column chromatography (eluent: appropriate ratio of hexane/ethyl acetate) to give a light yellow oil. The oil was recrystallized from anhydrous ethanol (200 mL) at -5 °C and the solid was collected to give 9-(4-bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide (23.7 g, 76.1% yield) as a white solid.
References
[1] Patent: CN106146385, 2016, A. Location in patent: Paragraph 0037; 0038
[2] Patent: WO2016/55934, 2016, A1. Location in patent: Paragraph 0124; 0133
[3] Patent: EP904262, 2004, B1. Location in patent: Page 145
9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide Preparation Products And Raw materials
Raw materials
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Preparation Products
9-(4-broMobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxaMide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai AQBioPharma Co., Ltd. | 13661411401 | yinglv.que@aqbiopharma.com.cn | China | 2930 | 58 |
| PharmaSea Pharmaceutical Tech. | 010-52980412 | chemsales@pharmasea.com.cn | China | 49 | 58 |
| Hunan Hezhong Pharmaceutical Co., Ltd. | 027-87614241 3310618156 | 3310618156@qq.com | China | 62 | 50 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Pharmasea Pharmaceutical Technology (Beijing) Co., Ltd | 010-57296878 15633144420 | zhengzs2000@aliyun.com | China | 27 | 58 |
| Alchemist-pharm chemical Technology Co. Ltd. | 0371-67991738 13783628208 | carl@alchemist-pharm.com | China | 1872 | 58 |
| 3A Chemicals | 400-668-9898 | service@3achem.com | China | 20557 | 58 |
