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3,4-Hexanedione

3,4-Hexanedione Structure
3,4-Hexanedione structure
CAS No.
4437-51-8
Chemical Name:
3,4-Hexanedione
Synonyms
hexane-3,4-dione;FEMA 3168;Bipropionyl;DIPROPIONYL;HEXANDION 3,4;3,4-Hexandion;3,4-Hexadione;3,4-DIOXOHEXANE;3,4-HEXANEDIONE;Diethyl diketone
CBNumber:
CB3288832
Molecular Formula:
C6H10O2
Molecular Weight:
114.14
MDL Number:
MFCD00010237
MOL File:
4437-51-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:11:52
Product description Number Pack Size Price
3,4-Hexanedione ≥95%, FG W316814 1 each $55.9
3,4-Hexanedione ≥95%, FG W316814 100g $141
3,4-Hexanedione ≥95%, FG W316814 250g $290
3,4-Hexanedione ≥95%, FG W316814 1kg $887
3,4-Hexanedione ≥95%, FG W316814 4kg $2460
More product size
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3,4-Hexanedione Properties

Melting point -10 °C
Boiling point 131 °C (lit.)
Density 0.939 g/mL at 25 °C (lit.)
refractive index n20/D 1.41(lit.)
FEMA 3168 | 3,4-HEXANEDIONE
FLAVIS Number 07.077 | Hexan-3,4-dione
Flash point 88 °F
storage temp. Sealed in dry,2-8°C
form Liquid
color Clear yellow
Odor at 1.00 % in dipropylene glycol. buttery toasted almond nutty caramellic
Odor Type buttery
biological source synthetic
Water Solubility 127 g/L (20 ºC)
JECFA Number 413
BRN 1700837
InChI 1S/C6H10O2/c1-3-5(7)6(8)4-2/h3-4H2,1-2H3
InChIKey KVFQMAZOBTXCAZ-UHFFFAOYSA-N
SMILES CCC(=O)C(=O)CC
LogP -0.27
CAS DataBase Reference 4437-51-8(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 3,4-HEXANEDIONE
EWG's Food Scores 1
FDA UNII 4M4NPR5VGD
NIST Chemistry Reference 3,4-Hexanedione(4437-51-8)
EPA Substance Registry System 3,4-Hexanedione (4437-51-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P210
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn
Risk Statements  10-36/38-20
Safety Statements  23-24/25-37/39-26-16
RIDADR  UN 1224 3/PG 3
WGK Germany  1
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29141900
Storage Class 3 - Flammable liquids
Hazard Classifications Flam. Liq. 3
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
2 0

3,4-Hexanedione price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W316814 3,4-Hexanedione ≥95%, FG 4437-51-8 1 each $55.9 2026-04-30 Buy
Sigma-Aldrich W316814 3,4-Hexanedione ≥95%, FG 4437-51-8 100g $141 2026-04-30 Buy
Sigma-Aldrich W316814 3,4-Hexanedione ≥95%, FG 4437-51-8 250g $290 2026-04-30 Buy
Sigma-Aldrich W316814 3,4-Hexanedione ≥95%, FG 4437-51-8 1kg $887 2026-04-30 Buy
Sigma-Aldrich W316814 3,4-Hexanedione ≥95%, FG 4437-51-8 4kg $2460 2026-04-30 Buy
Product number Packaging Price Buy
W316814 1 each $55.9 Buy
W316814 100g $141 Buy
W316814 250g $290 Buy
W316814 1kg $887 Buy
W316814 4kg $2460 Buy

3,4-Hexanedione Chemical Properties,Uses,Production

Description

3,4-Hexanedione has a pungent, unpleasant odor reminiscent of butter and a taste similar to that of diacetyl. May be prepared synthetically by condensation of ethyl propionate in the presence of sodium metal, followed by oxidation of the resulting propionin with copper acetate or ferric chloride.

Chemical Properties

3,4-Hexanedione has an aromatic, toasty, burnt, buttery, nutty, caramel-eggy, pungent odor.

Chemical Properties

clear yellow liquid

Occurrence

Reported found in cauliflower, coffee

Preparation

By condensation of ethyl propionate in the presence of sodium metal, followed by oxidation of the resulting propionin with copper acetate or ferric chloride.

Definition

ChEBI: 3,4-Hexanedione is an alpha-diketone.

Aroma threshold values

Aroma characteristics at 1.0%: sweet buttery, creamy, slightly cooked caramel and burnt sugary reminiscent of ghee and eggy vanillas.

Taste threshold values

Taste characteristics at 5 ppm: sweet buttery, creamy, pound cake and egg caramel-like with vanilla nuances.

General Description

The dermal irritation and sensitization potential of 3,4-hexanedione (used as constituents of synthetic flavoring agent) was studied using a murine model. The 3,4-hexanedione derivatives inhibited oxoglutarate transport.

Biochem/physiol Actions

Odor at 1.0%

3,4-Hexanedione Preparation Products And Raw materials

Raw materials

Ethyl propionate Copper (II) acetate monohydrate Ferric chloride

Preparation Products

2,3-Diethylpyrazine 2,3-Diethyl-5-methylpyrazine

3,4-Hexanedione Suppliers

Global( 260)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
JINING XINHE CHEMICAL CO., LTD 		+8615318402391 sales@xinhepharma.com China 809 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6366 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 9996 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
JINING XINHE CHEMICAL CO., LTD 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Shaanxi Dideu Medichem Co. Ltd 		58

View Lastest Price from 3,4-Hexanedione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-Hexanedione pictures 2026-03-20 3,4-Hexanedione
4437-51-8
 $10.00 1KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
3,4-Hexanedione pictures 2025-12-01 3,4-Hexanedione
4437-51-8
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
3,4-Hexanedione pictures 2025-06-20 3,4-Hexanedione
4437-51-8
 $12.00-20.00 1kg 99% 30 tons Hebei Yanxi Chemical Co., Ltd.

3,4-Hexanedione Spectrum

3,4-Hexanedione(4437-51-8)MS3,4-Hexanedione(4437-51-8)1HNMR3,4-Hexanedione(4437-51-8)13CNMR3,4-Hexanedione(4437-51-8)IR13,4-Hexanedione(4437-51-8)IR2

4437-51-8(3,4-Hexanedione)Related Search:

RHODIZONIC ACID DIHYDRATE 1,2-Cyclohexanedione DL-CAMPHORQUINONE (1S)-(+)-CAMPHORQUINONE 2,5-dibromo-3,4-hexanedione,2,5-DIBROMO-3,4-HEXANEDIONE, 95,2,5-dibromo-4-hexanedion
RHODIZONIC ACID DIPOTASSIUM SALT (1R)-(-)-CAMPHORQUINONE Sodium rhodizonate 2,5-Hexanedione 3-Methyl-1,2-cyclopentanedione
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3,4-HEXANEDIONE 3,4-DIOXOHEXANE 3,4-Hexandion HEXANDION 3,4 DIPROPIONYL DIETHYL-ALPHA, BETA-DI-KETONE FEMA 3168 Bipropionyl hexane-3,4-dione 3 4-HEXANEDIONE 90+% 1-CAPRYLENE-3-ALCOHOL 3,4-HEXANEDIONE FEMA NO.3168 3,4-HEXANEDIONE 96% Diethyl diketone 3,4-Hexadione 3,4-Hexanedione,96% 3,4-Hexanedione> 3,4-Hexanedione USP/EP/BP 4437-51-8 1704-35-6 CH2CH2COCOCH2CH3 Ketones Organic Building Blocks Building Blocks Carbonyl Compounds C3 to C6 C3 to C6 Carbonyl Compounds Ketones Building Blocks C3 to C6 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Alphabetical Listings Flavors and Fragrances G-H ketone Flavor Organics Industrial/Fine Chemicals