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ChemicalBook >> CAS DataBase List >>N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Structure
N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE structure
CAS No.
108825-65-6
Chemical Name:
N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE
Synonyms
C1632;Lin 28 163;Lin28 1632;Lin28-IN-1632;Lin28 inhibitor C1632;Lin281632, 10 mM in DMSO;Lin28-let-7 antagonist 1;Inhibitor,anxiolytic agent,Huh7 cells,inhibit,22Rv1,Lin281632;N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE;Acetamide,N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]-
CBNumber:
CB3292570
Molecular Formula:
C15H15N5O
Molecular Weight:
281.31
MDL Number:
MFCD01567008
MOL File:
108825-65-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:13:45
Product description Number Pack Size Price
Lin28 inhibitor C1632 ≥98% (HPLC) SML3673 10mg $109
Lin28 inhibitor C1632 ≥98% (HPLC) SML3673 50mg $439
Lin28 1632 ≥98% 22401 1mg $28
Lin28 1632 ≥98% 22401 5mg $70
Lin28 1632 ≥98% 22401 10mg $97
Request For Quotation

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Properties

Melting point 200 °C
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:28.13(Max Conc. mg/mL);100.0(Max Conc. mM)
Ethanol:28.13(Max Conc. mg/mL);100.0(Max Conc. mM)
form A crystalline solid
pka 0.57±0.30(Predicted)
color Off-white to light yellow
InChI 1S/C15H15N5O/c1-10-16-17-15-8-7-14(18-20(10)15)12-5-4-6-13(9-12)19(3)11(2)21/h4-9H,1-3H3
InChIKey WPAQLESUVYGUJZ-UHFFFAOYSA-N
SMILES [n]21nc(ccc2nnc1C)c3cc(ccc3)N(C)C(=O)C
FDA UNII WS1R0N3H0N
UNSPSC Code 12352200
NACRES NA.28

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P260-P280-P301+P312
Hazard Codes  Xi
WGK Germany  WGK 3
Hazard Note  Irritant
HS Code  2933998090
Storage Class 11 - Combustible Solids

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML3673 Lin28 inhibitor C1632 ≥98% (HPLC) 108825-65-6 10mg $109 2026-04-30 Buy
Sigma-Aldrich SML3673 Lin28 inhibitor C1632 ≥98% (HPLC) 108825-65-6 50mg $439 2026-04-30 Buy
Cayman Chemical 22401 Lin28 1632 ≥98% 108825-65-6 1mg $28 2026-04-30 Buy
Cayman Chemical 22401 Lin28 1632 ≥98% 108825-65-6 5mg $70 2026-04-30 Buy
Cayman Chemical 22401 Lin28 1632 ≥98% 108825-65-6 10mg $97 2026-04-30 Buy
Product number Packaging Price Buy
SML3673 10mg $109 Buy
SML3673 50mg $439 Buy
22401 1mg $28 Buy
22401 5mg $70 Buy
22401 10mg $97 Buy

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Chemical Properties,Uses,Production

Uses

Lin28 1632 is a small molecule inhibitor of Lin28.

Biological Activity

Compound 1632 (C1632) is a RNA-binding protein Lin28 inhibitor th at prevents Lin28-mediated inhibition of let-7 microRNA (miRNA) maturation by blocking Lin28 interaction with let-7 miRNA precursor (IC50 = 8 μM by ELISA using truncated pre-let-7a-2). C1632 specifically upregulates Huh7 cellular let-7a/g/f miRNA, but not RNU44 snoRNA (60 μM for 48h), inhibits the stemness and induces differentiation of mouse embryonic stem cells (mESCs, 20 μM for 48h), as well as inhibits the proliferation and stem-like properties of human cancer stem cells (CSCs) in 22Rv1 and Huh7 cultures (IC50 20-42 μM).

storage

Store at +4°C

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Suppliers

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30224 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 18971495150; sales@sun-shinechem.com China 1171 64
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17770 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22514 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3504 58
Supplier Advantage
Alchem Pharmtech,Inc. 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
BOC Sciences 65
Thermo Fisher Scientific 75
9ding chemical ( Shanghai) Limited 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 58

View Lastest Price from N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lin281632 pictures 2026-04-21 Lin281632
108825-65-6
 $30.00-108.00 99.84% 10g TargetMol Chemicals Inc.
  • Lin281632 pictures
  • Lin281632
    108825-65-6
  • $30.00-108.00
  • 99.84%
  • TargetMol Chemicals Inc.

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Spectrum

N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE(108825-65-6)1HNMR

108825-65-6(N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE)Related Search:

N-METHYL-3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)ANILINE 3-[(3-N,N-DIMETHYLAMINO)PHENYL]-1-PROPENE N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE
N-METHYL-N-[3-(3-METHYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL]ACETAMIDE Lin28 1632 Lin28-IN-1632 Acetamide,N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]- Lin 28 163 Lin28-let-7 antagonist 1 Inhibitor,anxiolytic agent,Huh7 cells,inhibit,22Rv1,Lin281632 C1632 Lin281632, 10 mM in DMSO Lin28 inhibitor C1632 108825-65-6 C15H15N5O