Alverine citrate
- CAS No.
- 5560-59-8
- Chemical Name:
- Alverine citrate
- Synonyms
- N-ETHYL-3,3-DIPHENYLDIPROPYLAMINE CITRATE SALT;GaMatran;CalMabel;Spacolin;SpasMona;Profenine;NSC 35459;Prophelan;Proverine;AntispasMin
- CBNumber:
- CB3303160
- Molecular Formula:
- C26H35NO7
- Molecular Weight:
- 473.57
- MDL Number:
- MFCD00035086
- MOL File:
- 5560-59-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Alverine citrate salt European Pharmacopoeia (EP) Reference Standard | Y0000687 | 5 mg | $244 |
| Alverine citrate salt | A0424 | 5g | $493 |
| Alverine citrate salt European Pharmacopoeia (EP) Reference Standard | Y0000687 | y0000687 | $223 |
| Alverine Citrate | A2896 | 1G | $36 |
| Alverine Citrate | A2896 | 5G | $108 |
| More product size | |||
| Melting point | 100-102° |
|---|---|
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water and in methylene chloride, sparingly soluble in ethanol (96 per cent). |
| form | Solid |
| color | White to Off-White |
| Major Application | pharmaceutical (small molecule) |
| InChIKey | RYHCACJBKCOBTJ-UHFFFAOYSA-N |
| SMILES | C(O)(C(=O)O)(CC(=O)O)CC(=O)O.C(C1C=CC=CC=1)CCN(CC)CCCC1C=CC=CC=1 |
| CAS DataBase Reference | 5560-59-8(CAS DataBase Reference) |
| FDA UNII | 9JFB58YK1E |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29214990 |
| Storage Class | 11 - Combustible Solids |
Alverine citrate price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000687 | Alverine citrate salt European Pharmacopoeia (EP) Reference Standard | 5560-59-8 | 5 mg | $244 | 2026-04-30 | Buy |
| Sigma-Aldrich | A0424 | Alverine citrate salt | 5560-59-8 | 5g | $493 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0000687 | Alverine citrate salt European Pharmacopoeia (EP) Reference Standard | 5560-59-8 | y0000687 | $223 | 2024-03-01 | Buy |
| TCI Chemical | A2896 | Alverine Citrate | 5560-59-8 | 1G | $36 | 2026-04-30 | Buy |
| TCI Chemical | A2896 | Alverine Citrate | 5560-59-8 | 5G | $108 | 2026-04-30 | Buy |
Alverine citrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Originator
Alverine citrate,Kemikos
Uses
Used for studies of pharmacological activity including:
- Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
- Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
- Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
- Drug effects viewed from a signal transduction network perspective
- Enhanced cytotoxic effect of proteasome inhibitor MG132
- Mechanism of action on phasic smooth muscles
Uses
An adrenergic-β3 receptor agonist. Antispasmodic.
Uses
anticholinergic
Definition
ChEBI: The citrate salt of alverine, resulting from the reaction of equimolar amounts of alvarine and citric acid. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used in the treatment of irritable bowel syndrome.
Manufacturing Process
2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium
hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt
as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was
obtained.
In practice it is usually used as citrate.
Therapeutic Function
Anticholinergic, Spasmolytic
References
[1] Patent: CN105461569, 2016, A. Location in patent: Paragraph 0023; 0049-0050
[2] Patent: CN103508898, 2016, B. Location in patent: Paragraph 0013; 0016; 0017
Alverine citrate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | info@longyupharma.com | China | 2421 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3365 | 58 |
View Lastest Price from Alverine citrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-16 | Alverine citrate
5560-59-8
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-06-02 | Alverine citrate
5560-59-8
|
$40.00 | 99.39% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-02 | Alverine citrate
5560-59-8
|
$40.00 | 99.39% | 10g | TargetMol Chemicals Inc. |
-
- Alverine citrate
5560-59-8
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Alverine citrate
5560-59-8
- $40.00
- 99.39%
- TargetMol Chemicals Inc.
-
- Alverine citrate
5560-59-8
- $40.00
- 99.39%
- TargetMol Chemicals Inc.
