2-chloro-3,4-dihydroxybenzoic acid
- CAS No.
- 87932-50-1
- Chemical Name:
- 2-chloro-3,4-dihydroxybenzoic acid
- Synonyms
- CHLORO-3,4-DIHYDROXYBENZOIC ACID;2-chloro-3,4-dihydroxybenzoic acid;Benzoic acid, 2-chloro-3,4-dihydroxy-;2-chloro-3,4-hydroxybenzenemacetic acid
- CBNumber:
- CB33040497
- Molecular Formula:
- C7H5ClO4
- Molecular Weight:
- 188.57
- MDL Number:
- MOL File:
- 87932-50-1.mol
- MSDS File:
- SDS
| Melting point | 216-217 °C |
|---|---|
| Boiling point | 385.5±42.0 °C(Predicted) |
| Density | 1.702±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.30±0.28(Predicted) |
| color | Pale Beige to Pale Brown |
| InChI | InChI=1S/C7H5ClO4/c8-5-3(7(11)12)1-2-4(9)6(5)10/h1-2,9-10H,(H,11,12) |
| InChIKey | IEKVQMDBVWMVMB-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(O)C(O)=C1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-chloro-3,4-dihydroxybenzoic acid price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C598093-50MG | 2-Chloro-3,4-dihydroxybenzoic acid | 87932-50-1 | 50mg | $270 | 2026-06-03 | Buy |
| TRC | TRC-C598093-10MG | 2-Chloro-3,4-dihydroxybenzoic acid | 87932-50-1 | 10mg | $66 | 2026-06-03 | Buy |
| TRC | TRC-C598093-100MG | 2-Chloro-3,4-dihydroxybenzoic acid | 87932-50-1 | 100mg | $409 | 2026-06-03 | Buy |
| Biosynth | FC158597 | 2-Chloro-3,4-dihydroxybenzoic acid | 87932-50-1 | 1g | $900 | 2026-06-04 | Buy |
| Biosynth | FC158597 | 2-Chloro-3,4-dihydroxybenzoic acid | 87932-50-1 | 0.5g | $900 | 2026-06-04 | Buy |
2-chloro-3,4-dihydroxybenzoic acid Chemical Properties, Uses, Production
Synthesis
52009-53-7
87932-50-1
General procedure for the synthesis of 2-chloro-3,4-dihydroxybenzoic acid from 2-chloro-3,4-dimethoxybenzoic acid: Example 1; Synthesis of Compound (I-1); Step (1) 2-chloro-3,4-dimethoxybenzoic acid (Compound 1) -> 2-chloro-3,4-dihydroxybenzoic acid (Compound 2). A dichloromethane (100 mL) suspension of 2-chloro-3,4-dimethoxybenzoic acid (10.83 g, 50 mmol) was cooled to 0 °C and then boron tribromide (BBr3, 18.91 mL, 200 mmol) was added slowly and dropwise over 15 min. The reaction mixture was continued to be stirred at 0 °C for 15 minutes, then brought to room temperature and stirred for 3 hours. Upon completion of the reaction, the mixture was slowly poured into a 2 M hydrochloric acid solution containing ice, and ethyl acetate (AcOEt) and tetrahydrofuran (THF) were added to promote layering. After removal of dichloromethane by evaporation under reduced pressure, the organic layer was separated. The organic layer was sequentially washed twice with water and once with saturated brine and then dried over anhydrous magnesium sulfate (MgSO4). After filtration to remove the desiccant, the filtrate was concentrated and dried under vacuum to afford 2-chloro-3,4-dihydroxybenzoic acid (Compound 2) as a light orange powder (5.46 g, 58% yield).
References
[1] Patent: EP2341053, 2011, A1. Location in patent: Page/Page column 42-43
[2] Yakugaku Zasshi, 1956, vol. 76, p. 1122,1125
[3] Chem.Abstr., 1957, p. 3505
2-chloro-3,4-dihydroxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-chloro-3,4-dihydroxybenzoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Baoji Didu Pharmaceutical and Chemical Co., Ltd | 029-81145305 17791533577 | 1021@dideu.com | China | 9997 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Shanghai Synteam Biochem CO.,ltd | +86-021-58380978 13482386415 | info@systeambc.com | China | 897 | 50 |
| Shanghai KunRaise Chemical Technology Co., Ltd | +86-021-50935922 | China | 715 | 55 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 9999 | 58 |
| Xi'an Pure&True New Materials Co., Ltd. | 18991218082 13572462239 | hongyan.zhao@xianpt.com | China | 120 | 58 |
| Tianjin Zhongcheng Mingyuan Technology Co., Ltd. | 13302022156 | 3506745780@qq.com | China | 168 | 58 |
View Latest Price from 2-chloro-3,4-dihydroxybenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | 2-chloro-3,4-dihydroxybenzoic acid
87932-50-1
|
$1.00-4.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-06-30 | 2-chloro-3,4-dihydroxybenzoic acid
87932-50-1
|
1KG | 98% | 1000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-15 | 2-chloro-3,4-dihydroxybenzoic acid
87932-50-1
|
$1.50 | 1g | 99.0% Min | 100 Tons | Shaanxi Didu New Materials Co. Ltd |
-
- 2-chloro-3,4-dihydroxybenzoic acid
87932-50-1
- $1.00-4.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-chloro-3,4-dihydroxybenzoic acid
87932-50-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-chloro-3,4-dihydroxybenzoic acid
87932-50-1
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
