Necitumumab
- CAS No.
- 906805-06-9
- Chemical Name:
- Necitumumab
- Synonyms
- Necitumumab;IMC-11F8/LY301221;Necitumumab (anti-EGFR);Research Grade Necitumumab;Research Grade Necitumumab(DHB86901)
- CBNumber:
- CB33044071
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 2BT4C47RUI |
| NCI Dictionary of Cancer Terms | necitumumab |
| NCI Drug Dictionary | necitumumab |
| ATC code | L01XC22 |
Necitumumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0031032 | Necitumumab 99.81% | 906805-06-9 | 1mg | $238 | 2026-06-04 | Buy |
| ChemScene | CS-0031032 | Necitumumab 99.81% | 906805-06-9 | 5mg | $715 | 2026-06-04 | Buy |
| ChemScene | CS-0031032 | Necitumumab 99.81% | 906805-06-9 | 10mg | $1137 | 2026-06-04 | Buy |
| Arctom | HY-P9964 | Necitumumab 99.81% | 906805-06-9 | 1mg | $168 | 2026-05-26 | Buy |
| Arctom | HY-P9964 | Necitumumab 99.81% | 906805-06-9 | 5mg | $490 | 2026-05-26 | Buy |
Necitumumab Chemical Properties, Uses, Production
Uses
Necitumumab is a human IgG monoclonal antibody directed against EGFR. Necitumumab can be used for research of NSCLC, colorectal cancer, etc[1].
Clinical Use
IgG1 monoclonal antibody:
Treatment of locally advanced or metastatic
epidermal growth factor receptor (EGFR) expressing
squamous non-small cell lung cancer
Drug interactions
Potentially hazardous interactions with other drugs
Live vaccines: avoid concomitant use.
Metabolism
The elimination routes of necitumumab are only partially documented, and involve degradation to peptides after being internalised into its target cells, proteolysis within the liver or the reticuloendothelial system, as well as nonspecific endocytosis.
References
[1] Garnock-Jones KP. Necitumumab: First Global Approval. Drugs. 2016 Feb;76(2):283-9. DOI:10.1007/s40265-015-0537-0
Necitumumab Preparation Products And Raw materials
Raw materials
Preparation Products
Necitumumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 4988 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Hubei Kele Fine Chemical Co., Ltd | 027-59101668 19945030958 | 2223443625@qq.com | China | 7998 | 58 |
| Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. | +86-027-59232304 15387063101 | 1276242629@qq.com | China | 9977 | 58 |
