N-Benzyloxycarbonyl-6-aminohexanoic acid
- CAS No.
- 1947-00-8
- Chemical Name:
- N-Benzyloxycarbonyl-6-aminohexanoic acid
- Synonyms
- VIB 19;VIB 197;Z-ACP-OH;NSC 92812;Z-ε-Ahx-OH;Z-6-ACA-OH;Z-e-Acp-OH;Z-(CH2)5-OH;Z-AHX(6)-OH;Z-ACP(6)-OH
- CBNumber:
- CB3304415
- Molecular Formula:
- C14H19NO4
- Molecular Weight:
- 265.3
- MDL Number:
- MFCD00004423
- MOL File:
- 1947-00-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Z-6-Aminohexanoic acid 98% | 299529 | 5g | $73.9 |
| N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) | C2757 | 5g | $66 |
| N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) | C2757 | 25g | $263 |
| N-Benzyloxycarbonyl-6-aminocaproicAcid | B285885 | 5G | $55 |
| N-Benzyloxycarbonyl-6-aminocaproicAcid | B285885 | 2g | $50 |
| More product size | |||
| Melting point | 54-57 °C(lit.) |
|---|---|
| Boiling point | 408.52°C (rough estimate) |
| Density | 1.162±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5110 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.76±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| BRN | 2288508 |
| Major Application | peptide synthesis |
| InChI | 1S/C14H19NO4/c16-13(17)9-5-2-6-10-15-14(18)19-11-12-7-3-1-4-8-12/h1,3-4,7-8H,2,5-6,9-11H2,(H,15,18)(H,16,17) |
| InChIKey | RXQDBVWDABAAHL-UHFFFAOYSA-N |
| SMILES | OC(=O)CCCCCNC(=O)OCc1ccccc1 |
| CAS DataBase Reference | 1947-00-8(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2924.29.7790 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
N-Benzyloxycarbonyl-6-aminohexanoic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 299529 | Z-6-Aminohexanoic acid 98% | 1947-00-8 | 5g | $73.9 | 2023-06-20 | Buy |
| TCI Chemical | C2757 | N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) | 1947-00-8 | 5g | $66 | 2026-04-30 | Buy |
| TCI Chemical | C2757 | N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) | 1947-00-8 | 25g | $263 | 2026-04-30 | Buy |
| TRC | B285885 | N-Benzyloxycarbonyl-6-aminocaproicAcid | 1947-00-8 | 5G | $55 | 2021-12-16 | Buy |
| TRC | B285885 | N-Benzyloxycarbonyl-6-aminocaproicAcid | 1947-00-8 | 2g | $50 | 2021-12-16 | Buy |
N-Benzyloxycarbonyl-6-aminohexanoic acid Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
peptide synthesis
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
501-53-1
60-32-2
1947-00-8
Benzyl chloroformate (1.63 mL, 11.45 mmol) was added slowly and dropwise to a stirred suspension of 6-aminohexanoic acid (1 g, 7.62 mmol) and K2CO3 (2.1 g, 15.2 mmol) in THF (20 mL). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the reaction was quenched with ethyl acetate and deionized water. The aqueous phase was separated and the pH of the aqueous phase was adjusted to 2 with 4N HCl and subsequently extracted twice with ethyl acetate (10 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The resulting crude product of Cbz-6-aminohexanoic acid was used directly in the next reaction without further purification in 99% yield.
References
[1] Journal of Organic Chemistry, 2007, vol. 72, # 16, p. 6162 - 6170
[2] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 15, p. 3332 - 3336
[3] Israel Journal of Chemistry, 2000, vol. 40, # 3-4, p. 335 - 341
[4] Synthetic Communications, 2004, vol. 34, # 13, p. 2415 - 2424
[5] Chemistry - A European Journal, 2008, vol. 14, # 27, p. 8169 - 8176
N-Benzyloxycarbonyl-6-aminohexanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1098 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
View Lastest Price from N-Benzyloxycarbonyl-6-aminohexanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-30 | N-Benzyloxycarbonyl-6-aminohexanoic acid
1947-00-8
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
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2020-01-08 | N-Benzyloxycarbonyl-6-aminohexanoic acid
1947-00-8
|
US $1.00 / g | 1g | 99.0% | 100kg | Career Henan Chemical Co |
-

- N-Benzyloxycarbonyl-6-aminohexanoic acid
1947-00-8
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-

- N-Benzyloxycarbonyl-6-aminohexanoic acid
1947-00-8
- US $1.00 / g
- 99.0%
- Career Henan Chemical Co





