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N-Benzyloxycarbonyl-6-aminohexanoic acid

CAS No.
1947-00-8
Chemical Name:
N-Benzyloxycarbonyl-6-aminohexanoic acid
Synonyms
VIB 19;VIB 197;Z-ACP-OH;NSC 92812;Z-ε-Ahx-OH;Z-6-ACA-OH;Z-e-Acp-OH;Z-(CH2)5-OH;Z-AHX(6)-OH;Z-ACP(6)-OH
CBNumber:
CB3304415
Molecular Formula:
C14H19NO4
Molecular Weight:
265.3
MDL Number:
MFCD00004423
MOL File:
1947-00-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:46
Product description Number Pack Size Price
Z-6-Aminohexanoic acid 98% 299529 5g $73.9
N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) C2757 5g $66
N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) C2757 25g $263
N-Benzyloxycarbonyl-6-aminocaproicAcid B285885 5G $55
N-Benzyloxycarbonyl-6-aminocaproicAcid B285885 2g $50
More product size

N-Benzyloxycarbonyl-6-aminohexanoic acid Properties

Melting point 54-57 °C(lit.)
Boiling point 408.52°C (rough estimate)
Density 1.162±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.5110 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 4.76±0.10(Predicted)
form Solid
color White to Off-White
BRN 2288508
Major Application peptide synthesis
InChI 1S/C14H19NO4/c16-13(17)9-5-2-6-10-15-14(18)19-11-12-7-3-1-4-8-12/h1,3-4,7-8H,2,5-6,9-11H2,(H,15,18)(H,16,17)
InChIKey RXQDBVWDABAAHL-UHFFFAOYSA-N
SMILES OC(=O)CCCCCNC(=O)OCc1ccccc1
CAS DataBase Reference 1947-00-8(CAS DataBase Reference)
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2924.29.7790
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
1 0

N-Benzyloxycarbonyl-6-aminohexanoic acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 299529 Z-6-Aminohexanoic acid 98% 1947-00-8 5g $73.9 2023-06-20 Buy
TCI Chemical C2757 N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) 1947-00-8 5g $66 2026-04-30 Buy
TCI Chemical C2757 N-Carbobenzoxy-6-aminohexanoic Acid >98.0%(HPLC)(T) 1947-00-8 25g $263 2026-04-30 Buy
TRC B285885 N-Benzyloxycarbonyl-6-aminocaproicAcid 1947-00-8 5G $55 2021-12-16 Buy
TRC B285885 N-Benzyloxycarbonyl-6-aminocaproicAcid 1947-00-8 2g $50 2021-12-16 Buy
Product number Packaging Price Buy
299529 5g $73.9 Buy
C2757 5g $66 Buy
C2757 25g $263 Buy
B285885 5G $55 Buy
B285885 2g $50 Buy

N-Benzyloxycarbonyl-6-aminohexanoic acid Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Benzyl chloroformate

501-53-1

6-Aminocaproic acid

60-32-2

N-Benzyloxycarbonyl-6-aminohexanoic acid

1947-00-8

Benzyl chloroformate (1.63 mL, 11.45 mmol) was added slowly and dropwise to a stirred suspension of 6-aminohexanoic acid (1 g, 7.62 mmol) and K2CO3 (2.1 g, 15.2 mmol) in THF (20 mL). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the reaction was quenched with ethyl acetate and deionized water. The aqueous phase was separated and the pH of the aqueous phase was adjusted to 2 with 4N HCl and subsequently extracted twice with ethyl acetate (10 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The resulting crude product of Cbz-6-aminohexanoic acid was used directly in the next reaction without further purification in 99% yield.

References

[1] Journal of Organic Chemistry, 2007, vol. 72, # 16, p. 6162 - 6170
[2] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 15, p. 3332 - 3336
[3] Israel Journal of Chemistry, 2000, vol. 40, # 3-4, p. 335 - 341
[4] Synthetic Communications, 2004, vol. 34, # 13, p. 2415 - 2424
[5] Chemistry - A European Journal, 2008, vol. 14, # 27, p. 8169 - 8176

N-Benzyloxycarbonyl-6-aminohexanoic acid Preparation Products And Raw materials

Global( 181)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+8618382028708 ni@enlaibio.com China 1098 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Changzhou PBpharmaceutical R&D Co.,Ltd
0519-83990708 info@pbpharm.com CHINA 498 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29794 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
GL Biochem (Shanghai) Ltd.
+86-021-61263370 +86-18901917034 CHINA 3904 58
GL Biochem(Binhai) Ltd.
+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58

View Lastest Price from N-Benzyloxycarbonyl-6-aminohexanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Benzyloxycarbonyl-6-aminohexanoic acid pictures 2026-04-30 N-Benzyloxycarbonyl-6-aminohexanoic acid
1947-00-8
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
N-Benzyloxycarbonyl-6-aminohexanoic acid pictures 2020-01-08 N-Benzyloxycarbonyl-6-aminohexanoic acid
1947-00-8
US $1.00 / g 1g 99.0% 100kg Career Henan Chemical Co
N-BENZYLOXYCARBONYL-6-AMINOCAPROIC ACID N-BENZYLOXYCARBONYL-6-AMINOHEXANOIC ACID N-CARBOBENZOXY-EPSILON-AMINOCAPROIC ACID N-GAMMA-CARBOBENZOXY-6-AMINOHEXANOIC ACID N-EPSILON-CARBOBENZOXY-6-AMINOCAPROIC ACID N-EPSILON-CBZ-EPSILON-AMINOCAPROIC ACID N-CBZ-6-AMINOCAPROIC ACID N-CBZ-6-AMINOHEXANOIC ACID Z-EPSILON-ACP-OH Z-EPSILONAHX-OH Z-EPSILON-AMINOCAPROIC ACID Z-(CH2)5-OH 6-(Cbz-amino)hexanoic acid Z-6-aminohexanoic acid99% Z-ε-Ahx-OH Z-6-ACA-OH Z-6-AMINOCAPROIC ACID Z-6-AMINOHEXANOIC ACID Z-AHX(6)-OH Z-ACP-OH Z-ACP(6)-OH LABOTEST-BB LT00455711 6-(CARBOBENZYLOXYAMINO)CAPROIC ACID 6-[[(phenylmethoxy)carbonyl]amino]hexanoic acid Cbz-ε-Aminocaproic acid 6-(N-Benzyloxycarbonylamino)hexanoic Acid NSC 92812 VIB 197 n-carbobenzoxy-ε-aminocaproic acid Carbobenzoxy-e-aminocaproic acid. Cbz- ε -Ahx-OH CBZ-.EPSILON.-AMINOCAPROIC ACID Z-e-Acp-OH VIB 19 Z-6-Aminohexanoic acid 98% 6-(Carbobenzyloxyamino)caproic acid,98% Cbz-ε- AMinocaproic acid Cbz-ε- AMinocaproic acid Z-6-aMinohexanoic acid, Z-eAhx-OH Z-e-aMinocaproic acid 6-(Benzyloxycarbonylamino)caproic acid N-Carbobenzoxy-6-aMinohexanoic Acid N-Carbobenzoxy-6-aminohexanoic Acid > CBZ-NH(CH2)5CO2H (6-(N-BENZYLOXYCARBONYLAMINO)HEXANOIC ACID) Hexanoic acid, 6-[[(phenylmethoxy)carbonyl]amino]- 6-(phenylmethoxycarbonylamino)hexanoicaci N-Benzyloxycarbonyl-epsilon-aminocaproic Acid N-Cbz-epsilon-aminocaproic Acid N-Benzyloxycarbonyl-6-aminohexanoic acid USP/EP/BP N-Cbz-ε-aminocaproic Acid 1947-00-8 C6H5CH2O2CNHCH25CO2H C6H5CH2OCONHCH25CO2H Amino Acids and Peptides BioChemical Biochemicals and Reagents Specialty Synthesis Unnatural Amino Acid Derivatives Modified Amino Acids