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4-Bromo-1-indanone

4-Bromo-1-indanone structure

CAS No.: 15115-60-3

Chemical Name:: 4-Bromo-1-indanone

Synonyms: 4-BROMO-2,3-DIHYDRO-1H-INDEN-1-ONE;SKL642;OZAN-001;4-bromoindanone;4-bromo-1-indanon;4-BROMO-1-INDANONE;4-BROMO-INDAN-1-ONE;1-Indanone, 4-bromo-;4-Bromo-1-indanone,97%;4-Bromo-1-indanone >

CBNumber:: CB3310546

Molecular Formula:: C9H7BrO

Molecular Weight:: 211.06

MDL Number:: MFCD01719772

MOL File:: 15115-60-3.mol

MSDS File:: SDS

Last updated:2026-03-04 10:44:01

Product description	Number	Pack Size	Price
4-Bromo-1-indanone 97%	644366	5g	$353
4-Bromo-1-indanone 97%	644366	1g	$83.5
4-Bromo-1-indanone >97.0%(GC)	B3801	1g	$23
4-Bromo-1-indanone >97.0%(GC)	B3801	5g	$43
4-Bromo-1-indanone	B687915	100g	$695
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4-Bromo-1-indanone Properties

Melting point	95-99 °C(lit.)
Boiling point	125°C/1.5mmHg(lit.)
Density	1.608±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	Crystalline Powder
color	Orange-brown
InChI	InChI=1S/C9H7BrO/c10-8-3-1-2-7-6(8)4-5-9(7)11/h1-3H,4-5H2
InChIKey	UVVYFYLSZIMKMC-UHFFFAOYSA-N
SMILES	C1(=O)C2=C(C(Br)=CC=C2)CC1
CAS DataBase Reference	15115-60-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	F68K258XWL
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H319-H315

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280i-P301+P312a-P337+P313-P501a-P305+P351+P338

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

Safety Statements

22-60-36

WGK Germany

RTECS

NK7536100

HS Code

29147000

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	1
2		0

4-Bromo-1-indanone price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	644366	4-Bromo-1-indanone 97%	15115-60-3	5g	$353	2023-06-20	Buy
Sigma-Aldrich	644366	4-Bromo-1-indanone 97%	15115-60-3	1g	$83.5	2022-05-15	Buy
TCI Chemical	B3801	4-Bromo-1-indanone >97.0%(GC)	15115-60-3	1g	$23	2026-03-19	Buy
TCI Chemical	B3801	4-Bromo-1-indanone >97.0%(GC)	15115-60-3	5g	$43	2026-03-19	Buy
TRC	B687915	4-Bromo-1-indanone	15115-60-3	100g	$695	2021-12-16	Buy

Product number	Packaging	Price	Buy
644366	5g	$353	Buy
644366	1g	$83.5	Buy
B3801	1g	$23	Buy
B3801	5g	$43	Buy
B687915	100g	$695	Buy

4-Bromo-1-indanone Chemical Properties,Uses,Production

Chemical Properties

Orange-brown crystalline powder

Uses

4-Bromo-1-indanone is used to prepare N''-indanyl-N-benzopyrazolyl ureas as TRPV1 antagonists for use as analgesics. It is also used to synthesize 1,4-dihydroindeno[1,2-c]pyrazoles as KDR kinase inhibitors.

General Description

4-Bromo-1-indanone is an organic synthetic or pharmaceutical intermediate compound that can be used to prepare the prescription drug Ozanimod. Ozanimod can be used to treat relapsing multiple sclerosis (MS), including clinical solitary syndrome, relapsing-remitting disease and active secondary progressive disease. This drug cannot cure multiple sclerosis, but it can slow down some disabling effects and reduce the frequency of disease recurrence. It can also be used to treat moderate to severe ulcerative colitis.

Synthesis

15115-58-9

15115-60-3

General procedure for the synthesis of 4-bromoinden-1-one from 3-(2-bromophenyl)propionic acid: trifluoromethanesulfonic acid (3 equiv.) was slowly added dropwise at 0 °C to an anhydrous dichloromethane (1.0 mL) solution of 3-(2-bromophenyl)propionic acid (0.5 mmol) which was placed in a 12 mL Q-tubepressure tube (provided by QLabtech). Subsequently, the reaction mixture was warmed to room temperature. A PTFE septum was placed on top of the reaction tube and sealed using the appropriate cap and pressure adapter. The sealed reaction tube was heated in an oil bath at 80°C. The progress of the reaction was monitored by thin layer chromatography (TLC) and gas chromatography-mass spectrometry (GC/MS) until the reactants completely disappeared. After completion of the reaction, the mixture was poured into ice water and extracted three times with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Finally, the target compound 4-bromoinden-1-one was isolated and purified from the crude product by fast column chromatography.

References

[1] Molecules, 2014, vol. 19, # 5, p. 5599 - 5610
[2] Patent: WO2018/106636, 2018, A1. Location in patent: Paragraph 100231
[3] Patent: US2015/25205, 2015, A1. Location in patent: Page/Page column
[4] Patent: WO2015/95188, 2015, A1. Location in patent: Paragraph 00161
[5] Patent: WO2003/99795, 2003, A1. Location in patent: Page 111

4-Bromo-1-indanone synthesis

Synthesis of 4-Bromo-1-indanone from Benzenepropanoyl chloride, 2-broMo-

4-Bromo-1-indanone Preparation Products And Raw materials

Raw materials

6-Bromoindanone 5-Bromo-1-indanone 4,7-Dibromo-2,3-dihydro-1H-inden-1-one 3-(2-Bromophenyl)propionic acid Benzenepropanoyl chloride, 2-broMo-

Trifluoromethanesulfonic acid Dichloromethane 1-Indanone

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Preparation Products

(R)-tert-butyl (4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 4-BROMO-2,3-DIHYDRO-1H-INDEN-1-OL 5-BROMOISOQUINOLIN-1(2H)-ONE 2-(2,3-dihydro-1H-inden-4-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane 2,3-dihydro-1-oxo-1H-indene-4-carbonitrile

4-FORMYL-INDAN-1-ONE 1,2-ETHANEDIOL KETAL 2-Allyl-5-broMo-3,4-dihydroisoquinolin-1(2H)-one 2,3-DIHYDRO-4-METHYL-1H-INDEN-1-OL 4-phenylindan-1-one

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4-Bromo-1-indanone Suppliers

Global( 381)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
GuiZhou DoSincerely biological technology Co.,Ltd.	+8613511983931	271622643@qq.com	China	9	58
PharmOrgSyn Laboratories Co., Ltd.	+86-021-38228826 +86-13916602830	sales@pharmorgsyn.cn	China	139	58
Jinan Qinmu Fine Chemical Co.,Ltd.	+8618660799346	sales@qinmuchem.com	China	1008	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
Hangzhou IKSChem Technology Co., Limited	+8613625816949	zheng@ikschem.com	China	979	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	+15184799099	lbaochemicals@gmail.com	China	671	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60

Supplier	Advantage
GuiZhou DoSincerely biological technology Co.,Ltd.	58
PharmOrgSyn Laboratories Co., Ltd.	58
Jinan Qinmu Fine Chemical Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
Hangzhou IKSChem Technology Co., Limited	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
Capot Chemical Co.,Ltd.	60

View Lastest Price from 4-Bromo-1-indanone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-16	4-Bromo-1-indanone 15115-60-3	US $0.00 / kg	1kg	98%	Customise	Hefei Lbao Physical & Chemical Science Co.,Ltd
2026-03-20	4-Bromo-1-indanone 15115-60-3	US $0.00-0.00 / KG	1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2026-03-04	4-Bromo-1-indanone 15115-60-3	US $0.00-0.00 / kg	1kg	≥98%	10000	GuiZhou DoSincerely biological technology Co.,Ltd.

4-Bromo-1-indanone
15115-60-3
US $0.00 / kg
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

4-Bromo-1-indanone
15115-60-3
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Bromo-1-indanone
15115-60-3
US $0.00-0.00 / kg
≥98%
GuiZhou DoSincerely biological technology Co.,Ltd.

4-Bromo-1-indanone Spectrum

4-Bromo-1-indanone(15115-60-3)¹HNMR

15115-60-3(4-Bromo-1-indanone)Related Search:

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4-bromo-2,3-dihydroinden-1-one 4-Bromo-1-indanone,97% 4-bromoindanone 1H-Inden-1-one, 4-bromo-2,3-dihydro- 1-Indanone, 4-bromo- 4-Bromo-1-indanone≥ 98%(GC) 4-bromo-1-indanon 4-BroMo-1-indanone, >95% 4-BROMO-INDAN-1-ONE 4-BROMO-1-INDANONE 4-BROMO-1-INDANONE HPLC 97% OZAN-001 4-Bromo-1-indanone > SKL642 4-BROMO-2,3-DIHYDRO-1H-INDEN-1-ONE 15115-60-3 13089-48-2 Carbonyl Compounds C9 Organic Building Blocks Ketones Building Blocks C9 Carbonyl Compounds Ketones Pharmaceutical intermediate Halides API intermediates Benzocycles