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ChemicalBook >> CAS DataBase List >>2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER Structure
2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER structure
CAS No.
108354-78-5
Chemical Name:
2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
Synonyms
AKOS B000467;AKOS BBB/011;ASISCHEM Z95321;AKOS BBS-00000703;CHEMBRDG-BB 3000467;ART-CHEM-BB B000467;methyl 2-amino-4,5,6,7-tetrahydrobenzothiophene-3-carboxylate;METHYL 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLATE;Methyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate;Methyl 2-aMino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate, 98%
CBNumber:
CB3312696
Molecular Formula:
C10H13NO2S
Molecular Weight:
211.28
MDL Number:
MFCD00130099
MOL File:
108354-78-5.mol
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
Methyl2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate M286615 5g $75
Methyl2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate M286615 1g $60
Methyl2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 2477CH 5g $104
Methyl2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 2477CH 100g $482
METHYL 2- AMINO- 4, 5, 6, 7- TETRAHYDRO- 1- BENZOTHIOPHENE- 3- CARBOXYLATE 95.00% CHM0030432 1G $648.81
More product size
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2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER Properties

Melting point 128-131°C
Boiling point 399.0±42.0 °C(Predicted)
Density 1.273±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 0.52±0.20(Predicted)
Appearance White to off-white Solid
CAS DataBase Reference 108354-78-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
HazardClass  IRRITANT
NFPA 704
0
2 0

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M286615 Methyl2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 108354-78-5 5g $75 2021-12-16 Buy
TRC M286615 Methyl2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 108354-78-5 1g $60 2021-12-16 Buy
AK Scientific 2477CH Methyl2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 108354-78-5 5g $104 2021-12-16 Buy
AK Scientific 2477CH Methyl2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 108354-78-5 100g $482 2021-12-16 Buy
American Custom Chemicals Corporation CHM0030432 METHYL 2- AMINO- 4, 5, 6, 7- TETRAHYDRO- 1- BENZOTHIOPHENE- 3- CARBOXYLATE 95.00% 108354-78-5 1G $648.81 2021-12-16 Buy
Product number Packaging Price Buy
M286615 5g $75 Buy
M286615 1g $60 Buy
2477CH 5g $104 Buy
2477CH 100g $482 Buy
CHM0030432 1G $648.81 Buy

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Uses,Production

Synthesis

Cyclohexanone

108-94-1

Methyl cyanoacetate

105-34-0

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER

108354-78-5

Methyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (Compound 1) was synthesized from cyclohexanone and methyl cyanoacetate by standard Gewald reaction. The procedure was as follows: to a stirred solution of cyclohexanone (4.91 g, 0.05 mol), methyl cyanoacetate (4.95 g, 0.05 mol), and sulfur (1.92 g, 0.06 mol) in 35 mL of ethanol, morpholine (4.4 g, 0.05 mol) was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was refluxed for 3 hours. After completion of the reaction, it was cooled to room temperature and the precipitate was collected by filtration. Purification by ethanol recrystallization gave a light yellow powdery product (8.6 g, 82% yield). The melting point of the product was 128.2-129.4 °C (literature value: 128-130 °C), and mass spectrometry (GC-MS) analysis showed a m/z of 211 [M + H]+ and fragment ion peaks of 179, 151, 125, 91, 77, 65, 53.

References

[1] Asian Journal of Chemistry, 2010, vol. 22, # 9, p. 7399 - 7404
[2] Organic and Biomolecular Chemistry, 2014, vol. 12, # 12, p. 1942 - 1956
[3] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 8, p. 1866 - 1871
[4] Tetrahedron, 2006, vol. 62, # 29, p. 7121 - 7131
[5] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 8, p. 1947 - 1953

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Cyclohexanone Methyl cyanoacetate Ethyl cyanoacetate Sulfur Ethanol
Morpholine

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Preparation Products

2-tert-ButoxycarbonylaMino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Changzhou Ditong Chemical Co.,Ltd 		+86-0519-88299272 info@edengenechem.com China 2176 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8826 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4017 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 20363 58
CD Chemical Group Limited 		+8615986615575 info@codchem.com China 20342 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53900 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Changzhou Ditong Chemical Co.,Ltd 		58
Wuhan Chemwish Technology Co., Ltd 		58
career henan chemical co 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		58
Dideu Industries Group Limited 		58
CD Chemical Group Limited 		58
Aladdin Scientific 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58

View Lastest Price from 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER pictures 2022-04-13 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
108354-78-5
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER pictures 2020-01-13 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
108354-78-5
 US $1.00 / KG 1g 99.0% 100kg Career Henan Chemical Co

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER Spectrum

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(108354-78-5)1HNMR

108354-78-5(2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER)Related Search:

2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER ETHYL 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE 1-Benzothiophene-3-carboxylic acid ETHYL 2-((4-NITROPHENYL)CARBONYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE ETHYL 2-ACETAMIDO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
ETHYL 2-[(2-CHLOROACETYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLATE 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER 4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL 2-((3-(2-CHLOROPHENYL)-5-METHYLISOXAZOL-4-YL)CARBONYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE ETHYL 2-(((4-CHLOROPHENYL)AMINO)CARBONYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
AKOS AUF1322 ETHYL 2-(((1,3-DIOXOINDAN-2-YLIDENE)METHYL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE AKOS 93369 ETHYL 2-[2-(2,4-DICHLOROPHENOXY)ACETAMIDO]-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE ETHYL 2-(((4-(TRIFLUOROMETHOXY)PHENYL)AMINO)CARBONYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE
ETHYL 2-(2,2,3,3,4,4,4-HEPTAFLUOROBUTANOYLAMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE AKOS 92930 BUTTPARK 123\48-20

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2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER 1-BENZOTHIOPHENE-3-CARBOXYLIC ACID, 2-AMINO-4,5,6,7-TETRAHYDRO-, METHYL ESTER AKOS B000467 AKOS BBS-00000703 AKOS BBB/011 METHYL 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLATE ASISCHEM Z95321 ART-CHEM-BB B000467 CHEMBRDG-BB 3000467 methyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(SALTDATA: FREE) Methyl 2-aMino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate, 98% Benzo[b]thiophene-3-carboxylic acid, 2-aMino-4,5,6,7-tetrahydro-, Methyl ester methyl 2-amino-4,5,6,7-tetrahydrobenzothiophene-3-carboxylate 2-amino-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid methyl ester 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER ISO 9001：2015 REACH Methyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 108354-78-5