ChemicalBook >> CAS DataBase List >>1,1,1-Trifluoroethyl-PEG2-azide

1,1,1-Trifluoroethyl-PEG2-azide

CAS No.
1835759-68-6
Chemical Name:
1,1,1-Trifluoroethyl-PEG2-azide
Synonyms
1,1,1-Trifluoroethyl-PEG2-azide
CBNumber:
CB33162799
Molecular Formula:
C6H10F3N3O2
Molecular Weight:
213.16
MDL Number:
MFCD29042341
MOL File:
1835759-68-6.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51

1,1,1-Trifluoroethyl-PEG2-azide Properties

storage temp. Storage temp. 2-8°C
form Liquid
color Colorless to light yellow

1,1,1-Trifluoroethyl-PEG2-azide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth KYC75968 1,1,1-Trifluoroethyl-PEG2-azide 1835759-68-6 250mg $875 2026-06-04 Buy
Biosynth KYC75968 1,1,1-Trifluoroethyl-PEG2-azide 1835759-68-6 500mg $1410 2026-06-04 Buy
ChemScene CS-0115153 1,1,1-Trifluoroethyl-PEG2-azide ≥97% 1835759-68-6 100mg $209 2026-06-04 Buy
ChemScene CS-0115153 1,1,1-Trifluoroethyl-PEG2-azide ≥97% 1835759-68-6 250mg $339 2026-06-04 Buy
ChemScene CS-0115153 1,1,1-Trifluoroethyl-PEG2-azide ≥97% 1835759-68-6 500mg $678 2026-06-04 Buy
Product number Packaging Price Buy
KYC75968 250mg $875 Buy
KYC75968 500mg $1410 Buy
CS-0115153 100mg $209 Buy
CS-0115153 250mg $339 Buy
CS-0115153 500mg $678 Buy

1,1,1-Trifluoroethyl-PEG2-azide Chemical Properties, Uses, Production

Description

1,1,1-Trifluoroethyl-PEG2-azide is a crosslinker containing an azide group and a trifluroethyl group. The azide group can participate in Click Chemistry reactions with reagents such as alkynes, DBCO and BCN. The hydrophilic PEG spacer increases solubility in aqueous media. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.

Uses

1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1,1,1-Trifluoroethyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

1,1,1-Trifluoroethyl-PEG2-azide Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80534353 19917294565 et@chemextension.com China 3904 55
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Alpha Biopharmaceuticals Co., Ltd 0411-39042497 sales@alphabiopharm.com China 1951 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Nextpeptide Inc +86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19904 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58

View Latest Price from 1,1,1-Trifluoroethyl-PEG2-azide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,1,1-Trifluoroethyl-PEG2-azide pictures 2026-05-11 1,1,1-Trifluoroethyl-PEG2-azide
1835759-68-6
$32.00-45.00 96.06% 10g TargetMol Chemicals Inc.
1,1,1-Trifluoroethyl-PEG2-azide pictures 2025-06-07 1,1,1-Trifluoroethyl-PEG2-azide
1835759-68-6
500mg >98.00% 500mg Xian confluore Biological Technology Co., Ltd.

1,1,1-Trifluoroethyl-PEG2-azide Spectrum

1,1,1-Trifluoroethyl-PEG2-azide 1835759-68-6