Hydroxy-PEG3-SS-PEG3-alcohol
- CAS No.
- 5662-81-7
- Chemical Name:
- Hydroxy-PEG3-SS-PEG3-alcohol
- Synonyms
- Hydroxy-PEG3-SS-PEG3-alcohol;3,6,9,16,19,22-Hexaoxa-12,13-dithiatetracosane-1,24-diol
- CBNumber:
- CB33363941
- Molecular Formula:
- C16H34O8S2
- Molecular Weight:
- 418.57
- MDL Number:
- MFCD28976684
- MOL File:
- 5662-81-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Hydroxy-PEG3-SS-PEG3-alcohol price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0109055 | Hydroxy-PEG3-SS-PEG3-alcohol ≥98% | 5662-81-7 | 100mg | $136 | 2026-06-04 | Buy |
| ChemScene | CS-0109055 | Hydroxy-PEG3-SS-PEG3-alcohol ≥98% | 5662-81-7 | 250mg | $231 | 2026-06-04 | Buy |
| ChemScene | CS-0109055 | Hydroxy-PEG3-SS-PEG3-alcohol ≥98% | 5662-81-7 | 1g | $622 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1446 | Hydroxy-PEG3-SS-PEG3-alcohol 95% | 5662-81-7 | 100mg | $168 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1446 | Hydroxy-PEG3-SS-PEG3-alcohol 95% | 5662-81-7 | 250mg | $283 | 2026-06-04 | Buy |
Hydroxy-PEG3-SS-PEG3-alcohol Chemical Properties, Uses, Production
Description
Hydroxy-PEG3-SS-PEG3-alcohol contains two terminal hydroxyl groups and a cleavable disulfide bond. The disulfide bond can be cleaved via reduction reactions using Dithiothreitol (DTT) reagent. The hydroxyl groups can be reacted to further derivatize the compound. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains.
Uses
Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50
Disulfide Cleavable Linker; Cleavable Linker
References
[1] Barrientos AG, et al. Gold glyconanoparticles: synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies. Chemistry. 2003 May 9;9(9):1909-21. DOI:10.1002/chem.200204544
Hydroxy-PEG3-SS-PEG3-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
Hydroxy-PEG3-SS-PEG3-alcohol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3147 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2982 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39718 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38923 | 58 |
