N-DBCO-N-bis(PEG2-acid)
- CAS No.
- 2110449-00-6
- Chemical Name:
- N-DBCO-N-bis(PEG2-acid)
- Synonyms
- N-DBCO-N-bis(PEG2-acid);N-DBCO-N-bis(PEG2-C2-acid)
- CBNumber:
- CB33373737
- Molecular Formula:
- C33H40N2O10
- Molecular Weight:
- 624.69
- MDL Number:
- MFCD29912780
- MOL File:
- 2110449-00-6.mol
N-DBCO-N-bis(PEG2-acid) Chemical Properties,Uses,Production
Description
N-DBCO-N-bis(PEG2-acid) is a branched click chemistry linker containing a DBCO and two PEG2-acid chains attached to a central nitrogen group. The DBCO group participates in copper-free Click Chemistry reactions with azide. Carboxylic acid (CO2H) allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable bond.
Uses
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-DBCO-N-bis(PEG2-C2-acid) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-DBCO-N-bis(PEG2-acid) Preparation Products And Raw materials
Raw materials
Preparation Products
N-DBCO-N-bis(PEG2-acid) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32433 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
Shanghai Send Pharmaceutical Technology Co., Ltd. | 021-58088081 Q2816483246 | hailey@shsendpharm.com | China | 2741 | 55 |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4952 | 58 |
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1992 | 58 |
Shanghai Minhan Pharmaceutical Technology Co., Ltd. | 17612188245 | 2816925681@qq.com | China | 2967 | 58 |
Guangzhou Younan Technology Co., Ltd | 020-82000279 18988968278 | YN_research@163.com | China | 3003 | 58 |
View Lastest Price from N-DBCO-N-bis(PEG2-acid) manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-07-21 | N-DBCO-N-bis(PEG2-C2-acid)
2110449-00-6
|
US $55.00 / mg | 10g | TargetMol Chemicals Inc. | |||
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2025-06-07 | N-DBCO-N-bis(PEG2-acid)
2110449-00-6
|
US $0.00 / mg | 250mg | >98.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- N-DBCO-N-bis(PEG2-C2-acid)
2110449-00-6
- US $55.00 / mg
- TargetMol Chemicals Inc.
-
- N-DBCO-N-bis(PEG2-acid)
2110449-00-6
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.