ChemicalBook >> CAS DataBase List >>FREUND'S COMPLETE ADJUVANT
FREUND'S COMPLETE ADJUVANT
- CAS No.
- 9007-81-2
- Chemical Name:
- FREUND'S COMPLETE ADJUVANT
- Synonyms
- FCA;F5881;abs9270;FREUND'S COMPLETE AD;FREUNDS COMPLETE ADJUVANT;FREUND'S ADJUVANT COMPLETE;FREUND'S COMPLETE ADJUVANT;ADJUVANT, COMPLETE(FREUND);Freund's Adjuvant Complete,FCA;Complete Freund's adjuvant (CFA)
- CBNumber:
- CB3341269
- Molecular Formula:
- C9H12FN3O5
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131105
- MOL File:
- Mol file
- MSDS File:
- SDS
Last updated:2026-05-28 05:09:11
| Product description | Number | Pack Size | Price |
| Freund’s Adjuvant, Complete cell suspension | F5881 | 10ml | $47.8 |
| Freund’s Complete Adjuvant, Modified, | 344289 | 1set | $318 |
| Complete Freund's adjuvant CFA ≥98% | CS-0864776 | 10mL | $32 |
| Complete Freund's adjuvant CFA ≥98% | CS-0864776 | 10mL*2 | $54 |
| Complete Freund's adjuvant CFA, 1 mg/ml | CS-1054729 | 10mL | $135 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H304 |
| Precautionary statements | P301+P310-P331-P405-P501 |
| Safety Statements | 23-24/25 |
| WGK Germany | 3 |
| RTECS | LS6860000 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Asp. Tox. 1 |
FREUND'S COMPLETE ADJUVANT price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F5881 | Freund’s Adjuvant, Complete cell suspension | 9007-81-2 | 10ml | $47.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 344289 | Freund’s Complete Adjuvant, Modified, | 9007-81-2 | 1set | $318 | 2026-04-30 | Buy |
| ChemScene | CS-0864776 | Complete Freund's adjuvant CFA ≥98% | 9007-81-2 | 10mL | $32 | 2026-06-04 | Buy |
| ChemScene | CS-0864776 | Complete Freund's adjuvant CFA ≥98% | 9007-81-2 | 10mL*2 | $54 | 2026-06-04 | Buy |
| ChemScene | CS-1054729 | Complete Freund's adjuvant CFA, 1 mg/ml | 9007-81-2 | 10mL | $135 | 2026-06-04 | Buy |
FREUND'S COMPLETE ADJUVANT Chemical Properties,Uses,Production
Uses
Immunization
Uses
Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion.
General Description
1 Set (10 x 10 ml) each containing yellow, oily, bacterial suspension.
Biochem/physiol Actions
The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.
in vivo
Complete Freund's adjuvant (CFA) induces experimental autoimmune myocarditis and neuropathic pain, with a relatively low plasma clearance rate (22%)[1][2][3][4].
Induction of experimental autoimmune myocarditis (EAM)[1]
Background
Complete Freund's adjuvant (CFA) induces myocarditis by activating the immune system and enhancing the antigen-specific immune response.
Specific Modeling Methods
Mice: A/J, BALB/c, and IL6KO BALB/c male 6-8-week-old
Administration: 5mg/ml s.c. twice
Administration: 5mg/ml s.c. twice
Note
(1) On day 0, all mice additionally received 500 ng of pertussis toxin (i.p.)
(2) On days 0 and 7, mice received subcutaneous injections peptide emulsified in CFA supplemented with 5 mg/mL of Mycobacterium tuberculosis, strain H37Ra.
(2) On days 0 and 7, mice received subcutaneous injections peptide emulsified in CFA supplemented with 5 mg/mL of Mycobacterium tuberculosis, strain H37Ra.
Modeling Indicators
Histological analysis: Myocarditis severity was assessed by histology and relative heart weight.
Molecular changes: Test serum levels of total IgG, IgG1, IgG2a, IgG2b, IL-1b and IL6.
Molecular changes: Test serum levels of total IgG, IgG1, IgG2a, IgG2b, IL-1b and IL6.
Correlated Product(s): Incomplete Freund's adjuvant (IFA) (HY-153808A); Complete Freund's adjuvant (CFA, 1 mg/ml) (HY-153808B)
Opposite Product(s): /
Induction of Neuropathic Pain[2][3]
Background
Complete Freund's adjuvant (CFA) releases inflammatory mediators TNF-α and IL-6 in body which can activate peripheral nerve endings and act on pain nerve endings, resulting in neuropathic pain[2][3].
Specific Modeling Methods
Mice: C57BL/6J male 8-week-old
Administration: 20 μl s.c. once
Administration: 20 μl s.c. once
Note
(1) Inject Complete Freund’s Adjuvant (CFA) without dilution into the plantar area of the hind paw.
(2) Tests PWT and PWL for both hind paws corresponding to before and 24, 48, 72 h after CFA injection.
(2) Tests PWT and PWL for both hind paws corresponding to before and 24, 48, 72 h after CFA injection.
Modeling Indicators
Behavior Observation: Detect paw withdrawal threshold (PWT) and paw withdrawal latency (PWL).
Correlated Product(s): Galantamine (HY-76299)
Opposite Product(s): Mecamylamine (HY-B1395A)
| Animal Model: | A/J, BALB/c, and IL6KO BALB/c male mice[1] |
| Dosage: | |
| Administration: | Subcutaneous Injectionon (sc); injected at days 0 and 7. EAM severity was analyzed by histology on day 21 (Repeated administration of CFA to animals can cause multiple injection-site effects, the most often observed are on site granulomas and pain) |
| Result: | Increased the relative proportion of CD11b+F4/80monocytes and CD11b+Gr1+ granulocytes. Expanded monocytes in the heart and in the spleen and those monocytes in the spleen make less IL-10 as well as more IL-6. |
FREUND'S COMPLETE ADJUVANT Preparation Products And Raw materials
Raw materials
Preparation Products
FREUND'S COMPLETE ADJUVANT Suppliers
Global( 221)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20582 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25021 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18729 | 57 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11705 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9815 | 79 |
View Lastest Price from FREUND'S COMPLETE ADJUVANT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-15 | FREUND'S COMPLETE ADJUVANT
9007-81-2
|
$1.00 | 1KG | 99.0% | 100kg | Career Henan Chemical Co |
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- FREUND'S COMPLETE ADJUVANT
9007-81-2
- $1.00
- 99.0%
- Career Henan Chemical Co
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IMJECT FREUND'S COMPLETE ADJUVANT
FREUNDS COMPLETE ADJUVANT
FREUND'S COMPLETE ADJUVANT
FREUND'S COMPLETE ADJUVANT, MODIFIED
FREUND'S COMPLETE ADJUVANT, MODIFIED, MYCOBACTERIUM BUTYRICUM
FREUND'S ADJUVANT COMPLETE
Freund's Adjuvant Complete,FCA
Immunostimulants,adjuvants, Freund's
4-Amino-1-(beta-D-arabinofuranosyl)-5-fluoro-2(1H)-pyrimidinone
FREUND'S COMPLETE ADJUVANT USP/EP/BP
abs9270
Freunds Complete Adjuvant, FCA/CFA)
Freund′s Complete Adjuvant, Modified, Mycobacterium butyricum
Complete Freund's adjuvant (CFA)
F5881
FCA
9007-81-2
Adjuvants
BioChemical
Antibody Purification and Characterization
Antibodies
Supplementary Products
