4-Chloroindoline
- CAS No.
- 41910-64-9
- Chemical Name:
- 4-Chloroindoline
- Synonyms
- 4-CHLOROINDOLINE;BUTTPARK 120\07-96;4-Chloroindoline 97%;4-CHLOROINDOLINE ,99%;D-3-Chlorophenylglycine;4-CHLORO-2,3-DIHYDRO-1H-INDOLE;1H-Indole, 4-chloro-2,3-dihydro-;4-CHLORO-2,3-DIHYDRO-1H-INDOLE HYDROCHLORIDE;4-Chloroindoline 4-Chloro-2,3-dihydro-1H-indole in stock Factory
- CBNumber:
- CB3366093
- Molecular Formula:
- C8H8ClN
- Molecular Weight:
- 153.61
- MDL Number:
- MFCD07371635
- MOL File:
- 41910-64-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloroindoline | C349505 | 500mg | $65 |
| 4-Chloroindoline | C349505 | 100mg | $45 |
| 4-Chloroindoline | FC51061 | 2g | $60 |
| 4-Chloroindoline 95+% | 38144 | 1g | $331 |
| 4-Chloroindoline 95+% | 38144 | 5G | $404 |
| More product size | |||
| Boiling point | 135 °C(Press: 10 Torr) |
|---|---|
| Density | 1.214±0.06 g/cm3(Predicted) |
| refractive index | 1.603 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 4.26±0.20(Predicted) |
| CAS DataBase Reference | 41910-64-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | 2735 |
| HazardClass | 8 |
| PackingGroup | Ⅲ |
| HS Code | 2933998090 |
4-Chloroindoline price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C349505 | 4-Chloroindoline | 41910-64-9 | 500mg | $65 | 2021-12-16 | Buy |
| TRC | C349505 | 4-Chloroindoline | 41910-64-9 | 100mg | $45 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC51061 | 4-Chloroindoline | 41910-64-9 | 2g | $60 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 38144 | 4-Chloroindoline 95+% | 41910-64-9 | 1g | $331 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 38144 | 4-Chloroindoline 95+% | 41910-64-9 | 5G | $404 | 2021-12-16 | Buy |
4-Chloroindoline Chemical Properties,Uses,Production
Synthesis
25235-85-2
41910-64-9
GENERAL STEPS: The synthesis of 4-chloroindoline from 4-chloroindole was carried out as follows: 4-chloroindole (20.0 g, 148 mmol) was dissolved in acetic acid (60 mL), followed by the addition of sodium cyanoborohydride (18.7 g, 296 mmol) in batches. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the mixture was slowly poured into 1500 mL of a 2 M NaOH aqueous solution. The aqueous phase was extracted with dichloromethane (CH2Cl2) and the organic layers were combined. The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give 4-chloroindoline (20.0 g, 98% yield). The product was confirmed by 1H NMR (400MHz, CDCl3): δ3.08 (2H, triple peak, J=8.4Hz), 3.62 (2H, triple peak, J=8.4Hz), 6.62-6.66 (1H, multiple peaks), 6.78-6.83 (1H, multiple peaks), 6.90 (1H, double double peaks, J=7.6,0.4Hz).
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 5, p. 1649 - 1666
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 166 - 178
[3] Journal of Medicinal Chemistry, 1998, vol. 41, # 10, p. 1598 - 1612
[4] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 21, p. 3105 - 3109
[5] Patent: US2008/27014, 2008, A1. Location in patent: Page/Page column 39
4-Chloroindoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | lee@unipharm-sd.com | China | 1202 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49968 | 58 |
View Lastest Price from 4-Chloroindoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-06-02 | 4-Chloroindoline 4-Chloro-2,3-dihydro-1H-indole in stock Factory
41910-64-9
|
US $1.00 / KG | 1KG | TOP 3 Factory in China | Top 3 production capacity Factory | Chemwill Asia Co.,Ltd. | |
 |
2020-01-10 | 4-Chloroindoline
41910-64-9
|
US $1.00 / KG | 1KG | 98% | 200kgs | Career Henan Chemical Co |
-
- 4-Chloroindoline 4-Chloro-2,3-dihydro-1H-indole in stock Factory
41910-64-9
- US $1.00 / KG
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- 4-Chloroindoline
41910-64-9
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
