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BOC-L-Asparagine

BOC-L-Asparagine structure

CAS No.: 7536-55-2

Chemical Name:: BOC-L-Asparagine

Synonyms: BOC-ASN;NαBOC-L-ASN;BOC-ASN-OH;15381_FLUKA;-Boc-Nω-Boc-N-βBOC-L-ASN-OH;Nα-BOC-L-Asn;-Fmoc-N-&beta

CBNumber:: CB3375413

Molecular Formula:: C9H16N2O5

Molecular Weight:: 232.23

MDL Number:: MFCD00038152

MOL File:: 7536-55-2.mol

MSDS File:: SDS

Last updated:2026-01-13 11:18:57

Product description	Number	Pack Size	Price
Boc-Asn-OH Novabiochem?	8.53039	25g	$52.1
Boc-Asn-OH Novabiochem?	8.53039	100g	$433
Boc-Asn-OH ≥98.5% (T)	15381	25g	$73.3
Nalpha-(tert-Butoxycarbonyl)-L-asparagine >98.0%(HPLC)(T)	B1627	10g	$23
Nα-Boc-L-asparagine	B622005	25g	$55
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BOC-L-Asparagine Properties

Melting point	175 °C (dec.)(lit.)
Boiling point	374.39°C (rough estimate)
Density	1.2896 (rough estimate)
refractive index	-7 ° (C=1, DMF)
Flash point	245°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	almost transparency in N,N-DMF
pka	3.79±0.10(Predicted)
form	Powder or Crystalline Powder
color	White
optical activity	[α]20/D 7.8±0.5°, c = 2% in DMF
BRN	1977963
Major Application	peptide synthesis
InChI	InChI=1S/C9H16N2O5/c1-9(2,3)16-8(15)11-5(7(13)14)4-6(10)12/h5H,4H2,1-3H3,(H2,10,12)(H,11,15)(H,13,14)/t5-/m0/s1
InChIKey	FYYSQDHBALBGHX-YFKPBYRVSA-N
SMILES	C(O)(=O)[C@H](CC(N)=O)NC(OC(C)(C)C)=O
CAS DataBase Reference	7536-55-2(CAS DataBase Reference)
EPA Substance Registry System	L-Asparagine, N2-[(1,1-dimethylethoxy)carbonyl]- (7536-55-2)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319

Precautionary statements

P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Risk Statements

20/21/22-36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

TSCA

TSCA listed

HS Code

2924 19 00

HazardClass

IRRITANT

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

BOC-L-Asparagine price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.53039	Boc-Asn-OH Novabiochem?	7536-55-2	25g	$52.1	2025-07-31	Buy
Sigma-Aldrich	8.53039	Boc-Asn-OH Novabiochem?	7536-55-2	100g	$433	2025-07-31	Buy
Sigma-Aldrich	15381	Boc-Asn-OH ≥98.5% (T)	7536-55-2	25g	$73.3	2025-07-31	Buy
TCI Chemical	B1627	Nalpha-(tert-Butoxycarbonyl)-L-asparagine >98.0%(HPLC)(T)	7536-55-2	10g	$23	2025-07-31	Buy
TRC	B622005	Nα-Boc-L-asparagine	7536-55-2	25g	$55	2021-12-16	Buy

Product number	Packaging	Price	Buy
8.53039	25g	$52.1	Buy
8.53039	100g	$433	Buy
15381	25g	$73.3	Buy
B1627	10g	$23	Buy
B622005	25g	$55	Buy

BOC-L-Asparagine Chemical Properties,Uses,Production

Chemical Properties

WHITE AMORPHOUS POWDER

Uses

Nα-Boc-L-asparagine is an N-Boc-protected form of L-Asparagine (A790005). L-Asparagine was first isolated by Robiquet and Vauquelin from asparagus juice (a high source of L-asparagine). L-Asparagine is often incorporated into proteins, and is a basis for some cancer therapies as certain cancerous cells require L-asparagine for growth.

Definition

ChEBI: The Nalpha-t-butoxycarbonyl derivative of L-asparagine

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

70-47-3

24424-99-5

7536-55-2

L-asparagine (15 g, 0.113 mol, 1.0 eq.) and sodium carbonate (12 g, 0.113 mol, 1.0 eq.) were dissolved in a solvent mixture of water (225 mL) and 1,4-dioxane (225 mL) at room temperature. To this solution was slowly added di-tert-butyl dicarbonate (30 g, 0.137 mol, 1.2 eq.) and the reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, 1,4-dioxane was removed by distillation under reduced pressure. Subsequently, the pH of the solution was adjusted to 2 with 37% hydrochloric acid, at which point a white solid precipitated. The solid product was collected by filtration, washed with water and dried under appropriate conditions. Finally, 24 g of BOC-L-asparagine was obtained in 91% yield. The product characterization data were as follows: melting point 175°C-180°C (literature value 175°C); 1H NMR (DMSO-D6) δ 12.5 (1H, br); 7.31 (1H, br); 6.91 (1H, br); 6.87 (1H, d, J=8.4 Hz); 4.23 (1H, q, J=7.7 Hz); 2.56- 2.36 (2H, m); 1.38 (9H, s).

References

[1] Patent: WO2005/21558, 2005, A2. Location in patent: Page/Page column 214
[2] Patent: US2006/189806, 2006, A1. Location in patent: Page/Page column 38
[3] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 8, p. 1185 - 1208
[4] Angewandte Chemie - International Edition, 2007, vol. 46, # 14, p. 2470 - 2477
[5] Organic Syntheses, 1985, vol. 63, p. 160 - 160

BOC-L-Asparagine synthesis

Synthesis of BOC-L-Asparagine from L-Asparagine and Di-tert-butyl dicarbonate

BOC-L-Asparagine Preparation Products And Raw materials

Raw materials

L-Asparagine L-Asparagine, N,N2-bis[(1,1-dimethylethoxy)carbonyl]- T -BUTYL-P-NITROPHENYL CARBONATE CARBONIC ACID TERT-BUTYL 2,4,5-TRICHLOROPHENYL ESTER BOC-ASP-OH

Carbonofluoridic acid, 1,1-dimethylethyl ester Di-tert-butyl dicarbonate Sodium carbonate tert-butyl azidoformate 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

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Preparation Products

BOC-BETA-CYANO-ALA-OH BOC-DAP(Z)-OH DCHA N-Boc-N'-xanthyl-L-asparagine 4-Nitrophenol (R)-Methyl 4-aMino-2-((tert-butoxycarbonyl)aMino)-4-oxobutanoate

BOC-L-Asparagine Suppliers

Global( 426)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8617390183901	cynthia@enlaibio.com	China	1098	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55
Zjartschem	+86-571 87238903	jocelynpan@zjarts.com	CHINA	988	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Anhui Dexinjia Biopharm Co., Ltd	+86-531-82375818 +86-15064153060	sales01@jndxj.com	China	312	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
Zjartschem	58
career henan chemical co	58
Anhui Dexinjia Biopharm Co., Ltd	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from BOC-L-Asparagine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-30	Boc-L-Asn-OH 7536-55-2	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-01-30	BOC-L-Asparagine 7536-55-2	US $15.00-50.00 / kg	1kg	NLT98%	5 ton per month	Anhui Dexinjia Biopharm Co., Ltd
2025-05-23	Boc-L-Asn-OH 7536-55-2	US $50.00 / kg	1kg	99	5000	Hebei Zhuanglai Chemical Trading Co Ltd

Boc-L-Asn-OH
7536-55-2
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

BOC-L-Asparagine
7536-55-2
US $15.00-50.00 / kg
NLT98%
Anhui Dexinjia Biopharm Co., Ltd

Boc-L-Asn-OH
7536-55-2
US $50.00 / kg
99
Hebei Zhuanglai Chemical Trading Co Ltd

BOC-L-Asparagine Spectrum

BOC-L-Asparagine(7536-55-2)MS BOC-L-Asparagine(7536-55-2)¹HNMR BOC-L-Asparagine(7536-55-2)¹³CNMR BOC-L-Asparagine(7536-55-2)IR1 BOC-L-Asparagine(7536-55-2)IR2

7536-55-2(BOC-L-Asparagine)Related Search:

L-Asparagine ASPARAGINASE D-(-)-Asparagine monohydrate Di-tert-butyl dicarbonate PYRAZOPHOS

2-Chloro-2-methylpropane 1,1'-Carbonyldiimidazole FMOC-ASN(TRT)-OPFP DI-TERT-BUTYL ETHER Carbonyl iron powder

NICKEL CARBONYL N-BOC-L-ASPARAGINE(XANTHYL) BOC-L-ASPARAGINE(TRITYL) BOC-ASP-OH NALPHA-BOC-D-ASPARAGINE,N-ALPHA-T-BOC-D-ASPARAGINE,BOC-D-ASPARAGINE,N-BOC-D-ASPARAGINE,NA-T-BOC-D-ASPARAGINE

DDZ-ASN-OH BOC-L-ASPARAGINE BENZYL ESTER BOC-L-ASPARAGINE N-HYDROXYSUCCINIMIDE ESTER

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T-BUTYLOXYCARBONYL-L-ASPARAGINE TBOC-L-ASPARAGINE N-TERT-BUTOXYCARBONYL-L-ASPARAGINE N-T-BUTOXYCARBONYL-L-ASPARAGINE N-T-BOC-L-ASPARAGINE N2-[(1,1-Dimethylethoxy)carbonyl]-L-asparagine NALPHA-BOC-L-ASPARAGINE N-ALPHA-T-BOC-L-ASPARAGINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-ASPARAGINE N-(ALPHA)-TERT-BUTOXYCARBONYL-L-ASPARAGINE N-ALPHA-T-BUTOXYCARBONYL-L-ASPARAGINE N-BOC-L-ASPARAGINE -Boc-N&omega -Boc-L-Ornithine Tert-butyl Ester Hydrochloride -Dimethyl-1,4-cyclohexadiene-1-ethanamine -Boc-N-&beta -bromoacetyl-L-2,3-diaminopropionic Acid -Methylphenethyl)-gluconamide -(4-Methylphenyl)sulfonyl)benzyl]diphenylphosphinic Amide -(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic Acid -Fmoc-N-&beta n2-[(1,1-dimethylethoxy)carbonyl]-l-asparagin BOC-ASN-OH BOC-ASN BOC-ASPARAGINE BOC-L-ASN BOC-L-ASPARAGINE BOC-L-ASN-OH BOC-L-ASPARAGINE-OH N-(a)-Boc-L-asparagine NA-T-BOC-L-ASPARAGINE N(ALPHA)-BOC-L-ASPARAGINE 99+% N-BOC-L-ASN-OH N-(-tert-Butoxycarbonyl-L-asparagine, 98+% (S)-4-aMino-2-((tert-butoxycarbonyl)aMino)-4-oxobutanoic acid L-2-tert-ButoxycarbonylaMino-succinaMicacid -(Tert-Butoxycarbonyl)-L-Asparagine N&alpha N_α-(tert-Butoxycarbonyl)-L-asparagine N2-[(tert-butoxy)carbonyl]-L-asparagine Boc-L-aspaD23-Ragine Boc-Asn-OH >=98.5% (T) (2S)-4-amino-2-(tert-butoxycarbonylamino)-4-keto-butyric acid (2S)-4-amino-2-(tert-butoxycarbonylamino)-4-oxo-butanoic acid (2S)-4-amino-2-[(tert-butoxy-oxomethyl)amino]-4-oxobutanoic acid 15381_FLUKA EINECS 231-405-2 (Tert-Butoxy)Carbonyl Asn-OH Boc-(S)-2-aminosuccinic acid 4-amide monohydrate Nα-Boc-L-asparagine≥ 98.5% (HPLC) -Dimethyl-3-pyridineethanamine -Benzoyl-DL-arginine &beta -Naphthylamide Hydrochloride -Bis(ethoxycarbonylethyl)-L-lysine Methyl Ester Boc-Asn-OH, BR -Diethylphenethylamine Hydrochloride -Boc-L-arginine Hydrochloride -Diethylphenethylamine-d5 Hydrochloride