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Boc-3-(2-Naphthyl)-L-alanine

Boc-3-(2-Naphthyl)-L-alanine Structure
Boc-3-(2-Naphthyl)-L-alanine structure
CAS No.
58438-04-3
Chemical Name:
Boc-3-(2-Naphthyl)-L-alanine
Synonyms
BOC-2-NAL-OH;BOC-NAL(2)-OH;BOC-L-2-NAL-OH;BOC-D-BETA-NAL-OH;BOC-ALA(2-NAPH)-OH;RARECHEM BK PT 0098;BOC-ALA(2-NAPHTHYL)-OH;BOC-2-L-NAPHTHYLALANINE;BOC-(2-naphthyl)alanine;BOC-L-2-NAPHTHYLALANINE
CBNumber:
CB3375448
Molecular Formula:
C18H21NO4
Molecular Weight:
315.36
MDL Number:
MFCD00079671
MOL File:
58438-04-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:18:10
Product description Number Pack Size Price
Boc-2-Nal-OH ≥97.0% (HPLC) 15483 1g $103
N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-L-alanine >98.0%(HPLC)(T) B3617 1g $98
N-Boc-3-(2-naphthyl)-L-alanine B657985 25g $385
Boc-3-(2-naphthyl)-L-alanine FB47420 25g $536
Boc-3-(2-naphthyl)-L-alanine,99.5%(ChiralHPLC) 99.5%(ChiralHPLC) 02586 25G $548.8
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Boc-3-(2-Naphthyl)-L-alanine Properties

Melting point 92-95 °C(lit.)
Boiling point 454.92°C (rough estimate)
Density 1.2164 (rough estimate)
refractive index 1.5740 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Ethanol
pka 3.88±0.30(Predicted)
form Solid
color Off-white
optical activity [α]20/D +45±2°, c = 1% in ethanol
BRN 4326467
Major Application peptide synthesis
InChI 1S/C18H21NO4/c1-18(2,3)23-17(22)19-15(16(20)21)11-12-8-9-13-6-4-5-7-14(13)10-12/h4-10,15H,11H2,1-3H3,(H,19,22)(H,20,21)/t15-/m0/s1
InChIKey URKWHOVNPHQQTM-HNNXBMFYSA-N
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(O)=O
CAS DataBase Reference 58438-04-3(CAS DataBase Reference)
UNSPSC Code 12352202
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Safety Statements  22-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29225090
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

Boc-3-(2-Naphthyl)-L-alanine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 15483 Boc-2-Nal-OH ≥97.0% (HPLC) 58438-04-3 1g $103 2025-07-31 Buy
TCI Chemical B3617 N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-L-alanine >98.0%(HPLC)(T) 58438-04-3 1g $98 2025-07-31 Buy
TRC B657985 N-Boc-3-(2-naphthyl)-L-alanine 58438-04-3 25g $385 2021-12-16 Buy
Biosynth Carbosynth FB47420 Boc-3-(2-naphthyl)-L-alanine 58438-04-3 25g $536 2021-12-16 Buy
Chem-Impex 02586 Boc-3-(2-naphthyl)-L-alanine,99.5%(ChiralHPLC) 99.5%(ChiralHPLC) 58438-04-3 25G $548.8 2021-12-16 Buy
Product number Packaging Price Buy
15483 1g $103 Buy
B3617 1g $98 Buy
B657985 25g $385 Buy
FB47420 25g $536 Buy
02586 25G $548.8 Buy

Boc-3-(2-Naphthyl)-L-alanine Chemical Properties,Uses,Production

Chemical Properties

beige to light brown powder

Uses

N-Boc-3-(2-naphthyl)-L-alanine Functions as a reagent for the synthesis of dipeptidyl nitriles as potent and reversible inhibitors of Cathepsin C

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

3-(2-NAPHTHYL)-L-ALANINE

6960-34-5

(E)-N-((tert-Butoxycarbonyl)oxy)benziMidoyl cyanide

74651-77-7

N-T-BOC-D-3-(2-NAPHTHYL)ALANINE

56583-58-5

The general procedure for the synthesis of 2-((tert-butoxycarbonyl)amino)-3-(naphthalen-2-yl)propanoic acid from the compound (CAS: 6960-34-5) and (E)-N-((tert-butoxycarbonyl)oxy)benzylidene cyanocyanide was as follows: 1. N-Butoxycarbonyl-L-3-(2-naphthalenyl)alanine (0.43 g, 2.0 mmol) was dissolved in a solvent mixture of dioxane (8 mL), water (8 mL) and triethylamine (4 mL). 2. BOC-ON (0.49 g, 2.0 mmol) was added and the reaction mixture was stirred overnight at room temperature under argon protection. 3. Upon completion of the reaction, the mixture was diluted with water (30 mL) and extracted with ethyl acetate (3 x 20 mL). 4. The aqueous layer was acidified to pH=4 with 10% citric acid solution and extracted with ethyl acetate (3 x 20 mL). 5. The organic phases were combined, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give a colorless oily product (0.52 g, 82% yield). 6. The product was characterized by 1H NMR (DMSO-d6): δ 7.8 (3H, m), 7.7 (1H, s), 7.4 (3H, m), 7.15 (1H, d), 4.2 (1H, m), 3.2 (1H, m), 2.9 (1H, m), 1.3 (9H, s).

References

[1] Patent: US5486597, 1996, A

Boc-3-(2-Naphthyl)-L-alanine Preparation Products And Raw materials

Raw materials

3-(2-NAPHTHYL)-L-ALANINE (E)-N-((tert-Butoxycarbonyl)oxy)benziMidoyl cyanide Triethylamine Water 1,4-Dioxane

Preparation Products

Boc-3-(2-Naphthyl)-L-alanine Suppliers

Global( 242)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29833 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2161 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034 CHINA 3904 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
GenicBio Limited 		58
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
GL Biochem (Shanghai) Ltd. 		58

View Lastest Price from Boc-3-(2-Naphthyl)-L-alanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-3-(2-Naphthyl)-L-alanine pictures 2019-07-06 Boc-3-(2-Naphthyl)-L-alanine
58438-04-3
 US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co

Boc-3-(2-Naphthyl)-L-alanine Spectrum

Boc-3-(2-Naphthyl)-L-alanine(58438-04-3)1HNMR

58438-04-3(Boc-3-(2-Naphthyl)-L-alanine)Related Search:

Phenprobamate N-Carbobenzyloxyglycine D-Alanine EC 2.6.1.2 L-Alanine
1-(1-NAPHTHYL)-2-THIOUREA tert-Butanol Boc-3-(2-Naphthyl)-D-alanine BOC-BETA-(1-NAPHTHYL)-L-ALANINE,N-ALPHA-T-BOC-BETA-(1-NAPHTHYL)-L-ALANINE,BOC-3-(1-NAPHTHYL)-L-ALANINE BOC-3-(1-NAPHTHYL)-D-ALANINE,BOC-BETA-(1-NAPHTHYL)-D-ALANINE,N-ALPHA-T-BOC-BETA-(1-NAPHTHYL)-D-ALANINE
(R)-3-(Boc-amino)-3-(2-naphthyl)propionic acid, L-Boc-3-(2-naphthyl)-β-alanine 3-(2-Naphthyl)-L-alanine 3-(2-NAPHTHYL)-L-ALANINE HYDROCHLORIDE BOC-3-(2-NAPHTHYL)-L-ALANINE MERRIFIELD RESIN D-BOC-3-(2-NAPHTHYL)-BETA-ALANINE
BOC-3-(1-PYRENYL)-L-ALANINE L-Alanine BOC-(S)-ALPHA-(2-NAPHTHALENYLMETHYL)-PROLINE

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BOC-ALA(2-NAPH)-OH BOC-ALA(2-NAPHTHYL)-OH BOC-ALA-BETA-(2-NAPHTHYL)-OH BOC-2-NAL-OH BOC-2-L-NAPHTHYLALANINE BOC-3-(2-NAPHTHYL)-ALANINE BOC-(2-naphthyl)alanine (S)-N-Boc-2-naphthylalanine, 95%, ee:98% (S)-N-BOC-2-Naphthylalanine,95%,98% ee 2-Naphthalenepropanoicacid, a-[[(1,1-diMethylethoxy)carbonyl]aMi N-Boc-3-(2-naphthyl)-L-alanine (S)-alpha-tert-Butoxycarbonylamino-2-naphthalenepropionic Acid (S)-alpha-(Boc-amino)-2-naphthalenepropionic Acid (2S)-2-[(tert-butoxycarbonyl)aMino]-3-(2-naphthyl)propanoic acid Boc-3-(2-naphthyl)-L-alanine, Boc-Ala(2-naphthyl)-OH Boc-3-(2-naphthyl)-L-alanine99% Boc-L-Ala(2-naphthyl)-OH (Tert-Butoxy)Carbonyl 2-Nal-OH BOC-3-(2-NAPHTHYL)-L-ALANINE N-BOC-3-(2-NAPHTHYL)-L-ALANINE N-ALPHA-T-BUTOXYCARBONYL-L-3-(2-NAPHTHYL)-ALANINE N-ALPHA-(TERT-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-L-ALANINE N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-L-ALANINE N-(TERT-BUTOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-L-ALANINE (S)-N-BOC-2-NAPHTHYLALANINE RARECHEM BK PT 0098 (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID (S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID N-T-BOC-L-3-(2-NAPHTHYL)ALANINE N-(TERT-BUTOXYCARBONYL)-3-(2-NAPHTHYL)-& (S)-BOC-3-(2-NAPHTHYL)-L-ALANINE N-alpha-tert-Butoxycarbonyl-3-(2-naphthyl)-L-alanin (S)-N-BOC-2-Naphthylalanine, 98% ee, 95% N-ALPHA-(T-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE 3-Naphth-2-yl-L-alanine, N-BOC protected BOC-D-BETA-NAL-OH BOC-L-3-(2-NAPHTYL)-ALANINE BOC-NAL(2)-OH BOC-L-2-NAL-OH BOC-L-2-NAPHTHYLALANINE BOC-L-3-(2-NAPHTHYL)-ALANINE BOC-BETA-(2-NAPHTHYL)-L-ALANINE (2S)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-(2-naphthalenyl)propanoic acid N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-L-alanine > 2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)- (S)-alpha-(Boc-amino)-2-naphthalenepropionic Acid (S)-alpha-tert-Butoxycarbonylamino-2-naphthalenepropionic Acid Boc-3-(2-Naphthyl)-L-alanine USP/EP/BP Boc-3-3(Naphthyl)-L-Alanine Boc-3-(2-Naphthyl)-L-Ala 58438-04-3 C18H221NO4 Specialty Synthesis Unnatural Amino Acid Derivatives Peptide Synthesis Alanine Derivatives a-amino Alanine [Ala, A]