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4-Bromo-2-fluorobenzaldehyde

4-Bromo-2-fluorobenzaldehyde structure

CAS No.: 57848-46-1

Chemical Name:: 4-Bromo-2-fluorobenzaldehyde

Synonyms: 2-FLUORO-4-B;4-Bromo-2-fluoro benzelhyde;4-BROMO-2-FLUOROBENZALDEHYDE;2-FLUORO-4-BROMOBENZALEDHYDE;2-FLUORO-4-BROMOBENZALDEHYDE;Benzaldehyde, 4-bromo-2-fluoro-;4-Bromo-2-fluorobenzaldehyde98%;4-Bromo-2-fluorobenzaldehyde,96%;4-Bromo-2-fluorobenzaldehyde 98%;4-Bromo-2-fluorobenzaldehyde >

CBNumber:: CB3377073

Molecular Formula:: C7H4BrFO

Molecular Weight:: 203.01

MDL Number:: MFCD00143261

MOL File:: 57848-46-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:24

Product description	Number	Pack Size	Price
4-Bromo-2-fluorobenzaldehyde 96%	465232	5g	$25
4-Bromo-2-fluorobenzaldehyde 96%	465232	25g	$119
4-Bromo-2-fluorobenzaldehyde >96.0%(GC)	B2002	5g	$69
4-Bromo-2-fluorobenzaldehyde >96.0%(GC)	B2002	25g	$196
4-Bromo-2-fluorobenzaldehyde	B684520	100g	$1055
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4-Bromo-2-fluorobenzaldehyde Properties

Melting point	58-62 °C (lit.)
Boiling point	42°C 19mm
Density	1.6698 (rough estimate)
refractive index	1.5700 (estimate)
Flash point	42°C/19mm
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
color	White to Orange to Green
Water Solubility	INSOLUBLE
Sensitive	Air Sensitive
BRN	7700208
InChI	InChI=1S/C7H4BrFO/c8-6-2-1-5(4-10)7(9)3-6/h1-4H
InChIKey	UPCARQPLANFGQJ-UHFFFAOYSA-N
SMILES	C(=O)C1=CC=C(Br)C=C1F
CAS DataBase Reference	57848-46-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Fluoro-4-bromobenzaldehyde(57848-46-1)
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

37/39-26-36

WGK Germany

Hazard Note

Irritant

HazardClass

IRRITANT, AIR SENSITIVE

HS Code

29130000

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

4-Bromo-2-fluorobenzaldehyde price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	465232	4-Bromo-2-fluorobenzaldehyde 96%	57848-46-1	5g	$25	2023-06-20	Buy
Sigma-Aldrich	465232	4-Bromo-2-fluorobenzaldehyde 96%	57848-46-1	25g	$119	2023-06-20	Buy
TCI Chemical	B2002	4-Bromo-2-fluorobenzaldehyde >96.0%(GC)	57848-46-1	5g	$69	2026-04-30	Buy
TCI Chemical	B2002	4-Bromo-2-fluorobenzaldehyde >96.0%(GC)	57848-46-1	25g	$196	2026-04-30	Buy
TRC	B684520	4-Bromo-2-fluorobenzaldehyde	57848-46-1	100g	$1055	2021-12-16	Buy

Product number	Packaging	Price	Buy
465232	5g	$25	Buy
465232	25g	$119	Buy
B2002	5g	$69	Buy
B2002	25g	$196	Buy
B684520	100g	$1055	Buy

4-Bromo-2-fluorobenzaldehyde Chemical Properties,Uses,Production

Chemical Properties

lightyellowtobeigecrystal

Uses

4-Bromo-2-fluorobenzaldehyde is used in the synthesis of Nigeglanine hydrobromide.

Uses

4-Bromo-2-fluorobenzaldehyde is used in the preparation of nigeglanine hydrobromide.

Uses

4-Bromo-2-fluorobenzaldehyde has been used in the preparation of:

2-functionalized aromatic monoaldehydes, via reaction with different secondary amines and phenol
fluorostilbenes
benzyl amine-based histamine H3 antagonist having serotonin reuptake activity
6-bromo-2-(4-bromo-2-fluorophenyl)-2,3-dihydro-4H-chromen-4-one

Synthesis

222978-01-0

57848-46-1

General procedure for the synthesis of 4-bromo-2-fluorobenzaldehyde from 4-bromo-3-fluorobenzyl alcohol: To a solution of 4-bromo-3-fluorobenzyl alcohol (7.9 g, 38.5 mmol) in dichloromethane (160.0 mL) was added sodium acetate (940 mg, 11.5 mmol) and pyridinium chlorochromate (10.8 g, 50.0 mmol) sequentially. The reaction mixture was stirred at room temperature and protected from light for 2 hours. After completion of the reaction, the mixture was diluted with ethyl acetate (1.0 L) and filtered through a diatomaceous earth pad. The filtrate was washed sequentially with aqueous sodium bicarbonate (600 mL) and water (600 mL) and subsequently dried with anhydrous sodium sulfate. After evaporation of the solvent under reduced pressure, the resulting crude product was further purified by column chromatography to afford 4-bromo-2-fluorobenzaldehyde as a white solid (5.0 g, 63% yield).

References

[1] Patent: WO2011/21209, 2011, A1. Location in patent: Page/Page column 38; 39
[2] Patent: US2012/101099, 2012, A1. Location in patent: Page/Page column 13; 14

4-Bromo-2-fluorobenzaldehyde Preparation Products And Raw materials

Raw materials

(4-BROMO-3-FLUOROPHENYL)METHANOL Dichloromethane Sodium acetate Pyridinium chlorochromate

Preparation Products

6-BROMO-BENZO[B]THIOPHENE Ethyl 6-broMo-1-benzothiophene-2-carboxylate 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde Methyl 1-methylindazole-6-carboxylate 4-BROMO-2-FLUOROBENZOYL CHLORIDE

4-BROMO-2-FLUOROBENZYL ALCOHOL 1-METHYL-1H-INDAZOL-5-AMINE 6-Bromo-1-methyl-1H-indazole 4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL 3'-Fluoro-4'-formyl-[1,1'-biphenyl]-4-carbonitrile

4-BROMO-2-FLUOROPHENYL CYCLOPROPYL KETONE ethyl 6-bromo-4-fluoro-1H-indole-2-carboxylate

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4-Bromo-2-fluorobenzaldehyde Suppliers

Global( 494)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13843	58
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Win-Win Chemical CO., Limited	0086-577-64498589	sales@win-winchemical.com	CHINA	998	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Win-Win Chemical CO., Limited	58
Shenzhen Nexconn Pharmatechs Ltd	58

View Lastest Price from 4-Bromo-2-fluorobenzaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	4-Bromo-2-fluorobenzaldehyde 57848-46-1	US $9.90 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2024-04-28	4-Bromo-2-fluorobenzaldehyde 57848-46-1	US $5.00 / kg	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd
2023-03-14	4-Bromo-2-fluorobenzaldehyde 57848-46-1	US $0.00-0.00 / kg	1kg	98%Min	1000kg	LY Global chemicals co.,ltd .

4-Bromo-2-fluorobenzaldehyde
57848-46-1
US $9.90 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Bromo-2-fluorobenzaldehyde
57848-46-1
US $5.00 / kg
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4-Bromo-2-fluorobenzaldehyde
57848-46-1
US $0.00-0.00 / kg
98%Min
LY Global chemicals co.,ltd .

4-Bromo-2-fluorobenzaldehyde Spectrum

4-Bromo-2-fluorobenzaldehyde(57848-46-1)MS 4-Bromo-2-fluorobenzaldehyde(57848-46-1)¹HNMR 4-Bromo-2-fluorobenzaldehyde(57848-46-1)¹³CNMR 4-Bromo-2-fluorobenzaldehyde(57848-46-1)IR1 4-Bromo-2-fluorobenzaldehyde(57848-46-1)IR2

57848-46-1(4-Bromo-2-fluorobenzaldehyde)Related Search:

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3-Bromoanisole Bromoxynil 4-Bromofluorobenzene 4-Bromo-2,6-difluorobenzoic acid 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE

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4-Bromo-2-fluorobenzaldehyde 98% 4-Bromo-2-fluorobenzaldehyde98% Benzaldehyde, 4-bromo-2-fluoro- 4-Bromo-2-fluorobenzaldehyde,96% 4-BroMo-2-fluorobenzaldehyde, 96% 5GR 4-BroMo-2-fluorobenzaldehyde, 97+% 2-FLUORO-4-BROMOBENZALDEHYDE 2-FLUORO-4-BROMOBENZALEDHYDE 4-BROMO-2-FLUOROBENZALDEHYDE 4-Bromo-2-Fluorobenzaldehyde 2-Fluoro-4-Bromobenzaldehyde 2-FLUORO-4-B 4-Bromo-2-fluorobenzaldehyde > 4-Bromo-2-fluorobenzaldehyde ISO 9001：2015 REACH 4-Bromo-2-fluoro benzelhyde (2-Bromo-5-methoxy-29-methyl-phenyl)-methano 57848-46-1 BrC6H3FCHO ALDEHYDE Organic Building Blocks Aldehydes Building Blocks C7 Carbonyl Compounds Benzaldehyde (Building Blocks for Liquid Crystals) Building Blocks for Liquid Crystals FINE Chemical & INTERMEDIATES Aromatic Aldehydes & Derivatives (substituted) Fluorobenzene Fluorin-contained benzaldehyde series Aldehydes C7 Carbonyl Compounds Benzene series Benzaldehyde Miscellaneous Adehydes, Acetals & Ketones Bromine Compounds Fluorine Compounds Benzaldehyde (Building Blocks for Liquid Crystals) Building Blocks for Liquid Crystals Functional Materials bc0001