ANTI-SHPS-1
- CAS No.
- Chemical Name:
- ANTI-SHPS-1
- Synonyms
- ANTI-BIT;ANTI-P84;Anti-MFR;Anti-SIRP;ANTI-MYD-1;Anti-LENG3;Anti-SIRPa;Anti-P84N5;ANTI-SHPS-1;Anti-CD172A
- CBNumber:
- CB3377927
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01634182
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| WGK Germany | 1 |
| Storage Class | 10 - Combustible liquids |
ANTI-SHPS-1 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | WH0140885M1 | Monoclonal Anti-PTPNS1 antibody produced in mouse clone 1D10, purified immunoglobulin, buffered aqueous solution | 50 μg | $580 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB3500202 | Anti-SIRPα antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 100μg | $584 | 2026-04-30 | Buy | |
| Sigma-Aldrich | HPA058511 | Anti-SIRPA antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody | 100 μL | $607 | 2026-04-30 | Buy | |
| Sigma-Aldrich | HPA054437 | Anti-SIRPA antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody | 100 μL | $607 | 2026-04-30 | Buy | |
| Sigma-Aldrich | HPA043532 | Anti-PPP1R12C antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $667 | 2026-04-30 | Buy |
ANTI-SHPS-1 Chemical Properties,Uses,Production
Uses
Anti-SIRPα1 may be used in immunoblotting application at a working concentration of 4 μg/mL using mouse myeloblast whole cell lysate. The antibody is suitable for protein microarray and immunoprecipitation.
General Description
Signal regulatory proteins (SIRPs) are a class of transmembrane glycoproteins with extracellular domains resembling the immunoglobulins. The SIRP family consists of three members, SIRPα, SIRPβ and SIRPγ. In rat there are two SIRPβ members, SIRPβ1 and SIRPβ2. SIRP members are ubiquitously present on the surface of all immune system cells. SIRPα (SHP-1) is expressed on neurons, myeloid dendritic cells, mast cells, macrophages and granulocytes. The most studied role of SIRPα is the inhibition of host cell phagocytosis by the macrophages. SIRPα is reportedly involved in clearance of aged erythrocytes, regulation of production of TNF-α induced by LPS, controlling the migration of myeloid cells and maturation of dendritic cells
Anti-SIRPα1 (SHPS-1) recognizes the differentially glycosylated forms of SIRPα1(SHPS-1) of 130, 100 and 65 kDa. It also detects a single band at 50 kDa.
Biological Activity
Signal regulatory protein α (SIRPα) acts as a modulator of immune responses. It has a role in the migration, adhesion, growth and differentiation of cells. SIRPα associates with cluster of differentiation 47 (CD47) and prevents phagocytosis by macrophages.
ANTI-SHPS-1 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-SHPS-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Atlas antibodies | -- | order@atlasantibodies.com | China | 6586 | 58 |
| Merck KGaA | -- | ordercn@merckgroup.com | China | 6376 | 58 |
| Nanjing Weiwo Biotechnology Co., Ltd. | -- | CHINA | 6423 | 58 | |
| Neobioscience Co., Ltd. | -- | info@neobioscience.com | CHINA | 6192 | 58 |
| Riedel-de Haen AG | -- | United States | 6624 | 87 | |
| SIGMA-RBI | -- | Switzerland | 6825 | 91 | |
| EMD Biosciences, Inc. | -- | technical@calbiochem.com | United States | 6527 | 66 |
| VWR International | -- | solutions@vwr.com | United Kingdom | 6523 | 82 |
| BIOTREND Chemikalien GmbH | -- | jaeger@biotrend.com | Germany | 6114 | 76 |
| BD Biosciences | -- | United States | 5012 | 82 |
| Supplier | Advantage |
|---|---|
| Atlas antibodies | 58 |
| Merck KGaA | 58 |
| Nanjing Weiwo Biotechnology Co., Ltd. | 58 |
| Neobioscience Co., Ltd. | 58 |
| Riedel-de Haen AG | 87 |
| SIGMA-RBI | 91 |
| EMD Biosciences, Inc. | 66 |
| VWR International | 82 |
| BIOTREND Chemikalien GmbH | 76 |
| BD Biosciences | 82 |
