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4-Bromobenzenesulfonamide

CAS No.
701-34-8
Chemical Name:
4-Bromobenzenesulfonamide
Synonyms
AKOS 206-12;p-bromo-benzenesulfonamid;P-BROMOBENZENESULFONAMIDE;4-BROMOBENZENESULFONAMIDE;Bromo Benzene Sulphonamide;4-BROMOBENZENESULPHONAMIDE;Benzenesulfonamide, p-bromo-;Benzenesulfonamide, 4-bromo-;4-Bromobenzenesulphonamide 98%;4-Bromobenzenesulphonamide-98%
CBNumber:
CB3379855
Molecular Formula:
C6H6BrNO2S
Molecular Weight:
236.09
MDL Number:
MFCD00051977
MOL File:
701-34-8.mol
MSDS File:
SDS
Last updated:2026-01-13 11:18:02
Product description Number Pack Size Price
4-Bromobenzenesulfonamide ≥99.0% (T) 16374 5g $51.66
4-Bromobenzenesulfonamide ≥99.0% (T) 16374 100g $128
4-Bromobenzenesulfonamide B682628 500mg $45
4-Bromobenzenesulfonamide 98.0% 8669-9-X9 25g $47
4-Bromobenzenesulfonamide 98% 023739 100g $104
More product size

4-Bromobenzenesulfonamide Properties

Melting point 163-167 °C
Boiling point 360.7°C (rough estimate)
Density 1.8000 (estimate)
refractive index 1.6140 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.89±0.10(Predicted)
form Solid
color White to Off-White
Water Solubility 991.6mg/L(15 ºC)
BRN 2691657
InChI 1S/C6H6BrNO2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,(H2,8,9,10)
InChIKey STYQHICBPYRHQK-UHFFFAOYSA-N
SMILES NS(=O)(=O)c1ccc(Br)cc1
CAS DataBase Reference 701-34-8(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 4-Bromobenzenesulfonamide(701-34-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS07
Signal word  Warning
Hazard statements  H301-H315-H319-H335-H302
Precautionary statements  P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  DB0550000
HazardClass  IRRITANT
HS Code  2935909099
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
NFPA 704
1
2 0

4-Bromobenzenesulfonamide price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 16374 4-Bromobenzenesulfonamide ≥99.0% (T) 701-34-8 5g $51.66 2024-03-01 Buy
Sigma-Aldrich 16374 4-Bromobenzenesulfonamide ≥99.0% (T) 701-34-8 100g $128 2022-05-15 Buy
TRC B682628 4-Bromobenzenesulfonamide 701-34-8 500mg $45 2021-12-16 Buy
SynQuest Laboratories 8669-9-X9 4-Bromobenzenesulfonamide 98.0% 701-34-8 25g $47 2021-12-16 Buy
Matrix Scientific 023739 4-Bromobenzenesulfonamide 98% 701-34-8 100g $104 2021-12-16 Buy
Product number Packaging Price Buy
16374 5g $51.66 Buy
16374 100g $128 Buy
B682628 500mg $45 Buy
8669-9-X9 25g $47 Buy
023739 100g $104 Buy

4-Bromobenzenesulfonamide Chemical Properties,Uses,Production

Uses

4-Bromobenzenesulfonamide was used as reagent in preparation of cobalt(III) complexes of N,R-sulfonyldithiocarbimate anion. It was also used in the synthesis of 2-, 3- and 4-(substituted-phenylethynyl)benzenesulfonamides.

General Description

4-Bromobenzenesulfonamide is a metabolite of ebrotidine, a new H2-receptor antagonist.

Synthesis

4-Bromobenzenesulfonyl chloride

98-58-8

4-Bromobenzenesulfonamide

701-34-8

Preparation of 4-bromobenzenesulfonamide: 4-bromobenzenesulfonyl chloride (1.0 g, 3.9 mmol) was dissolved in methanol (5 mL), methanol/ammonia solution (5 mL, excess) was added, and the mixture was mixed in a 25 mL single-neck flask. The reaction mixture was stirred overnight at room temperature under nitrogen protection. On the next day, the reaction solution was concentrated under reduced pressure to give p-bromobenzenesulfonamide (1.13 g, 100% yield) as a white solid. The product was confirmed by ion spray mass spectrometry (m/z 235.9 [M*]) and could be used for subsequent reactions without further purification.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 14, p. 3880 - 3885
[2] Patent: US2004/63680, 2004, A1
[3] Patent: US7034045, 2006, B1. Location in patent: Page/Page column 83
[4] Journal of Medicinal Chemistry, 2018, vol. 61, # 11, p. 4860 - 4882
[5] RSC Advances, 2014, vol. 4, # 24, p. 12119 - 12126

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View Lastest Price from 4-Bromobenzenesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromobenzenesulfonamide pictures 2026-03-20 4-Bromobenzenesulfonamide
701-34-8
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
4-Bromobenzenesulfonamide pictures 2025-12-12 4-Bromobenzenesulfonamide
701-34-8
US $1.00-4.00 / KG 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd
4-Bromobenzenesulfonamide pictures 2025-12-01 4-Bromobenzenesulfonamide
701-34-8
US $0.00 / kg 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
Bromo Benzene Sulphonamide 4-Bromobenzenesulfonamide, 97+% AKOS 206-12 Benzenesulfonamide, 4-bromo- Benzenesulfonamide, p-bromo- p-bromo-benzenesulfonamid 4-BroMobenzenesulfonaMide >=99.0% (T) P-BROMOBENZENESULFONAMIDE 4-BROMOBENZENESULPHONAMIDE 4-BROMOBENZENESULFONAMIDE 4-Bromobenzenesulphonamide 98% 4-BROMOBENZENESULFONAMIDE, 98 % 4-Bromobenzenesulfonamide USP/EP/BP 4-Bromobenzenesulfonamide ISO 9001:2015 REACH 4-Bromobenzenesulphonamide-98% 701-34-8 107-34-8 Br1C6H6N1O2S1 Building Blocks Organic Building Blocks Sulfonamides/Sulfinamides Sulfur Compounds blocks Bromides Sulfonamides Aryl Halogenated Organohalides