PYRIDINE-2-THIOAMIDE
- CAS No.
- 5346-38-3
- Chemical Name:
- PYRIDINE-2-THIOAMIDE
- Synonyms
- 2-Pyridylthioamide;PYRIDINE-2-CARBOTHIOAMIDE;thio-picolinamid;Thiopicolinamide;picolinothioamide;2-thiopicolinamide;CHEMBRDG-BB 4017339;2-Pyridinethioamide;PYRIDINE-2-THIOAMIDE;picolinicacidthioamide
- CBNumber:
- CB3393268
- Molecular Formula:
- C6H6N2S
- Molecular Weight:
- 138.19
- MDL Number:
- MFCD00087576
- MOL File:
- 5346-38-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Pyridinethioamide 97% | 699047 | 5g | $34.1 |
| Thiopicolinamide >97.0%(GC)(T) | T2618 | 1g | $17 |
| Thiopicolinamide >97.0%(GC)(T) | T2618 | 5g | $54 |
| 2-Pyridylthioamide ≥98% | 13043 | 1g | $13 |
| 2-Pyridylthioamide ≥98% | 13043 | 5g | $44 |
| Melting point | 134-138 °C |
|---|---|
| Boiling point | 278.9±32.0 °C(Predicted) |
| Density | 1.265±0.06 g/cm3(Predicted) |
| Flash point | 160 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml |
| pka | 11.98±0.29(Predicted) |
| form | Crystalline Powder |
| color | Yellow |
| InChI | InChI=1S/C6H6N2S/c7-6(9)5-3-1-2-4-8-5/h1-4H,(H2,7,9) |
| InChIKey | HYKQYVSNFPWGKQ-UHFFFAOYSA-N |
| SMILES | C1(C(N)=S)=NC=CC=C1 |
| CAS DataBase Reference | 5346-38-3(CAS DataBase Reference) |
| FDA UNII | YN34RW97C7 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H317-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-43-41-37/38-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TJ4305500 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333999 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
|||||||||
| NFPA 704 |
|
PYRIDINE-2-THIOAMIDE price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 699047 | 2-Pyridinethioamide 97% | 5346-38-3 | 5g | $34.1 | 2026-04-30 | Buy |
| TCI Chemical | T2618 | Thiopicolinamide >97.0%(GC)(T) | 5346-38-3 | 1g | $17 | 2026-04-30 | Buy |
| TCI Chemical | T2618 | Thiopicolinamide >97.0%(GC)(T) | 5346-38-3 | 5g | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 13043 | 2-Pyridylthioamide ≥98% | 5346-38-3 | 1g | $13 | 2026-04-30 | Buy |
| Cayman Chemical | 13043 | 2-Pyridylthioamide ≥98% | 5346-38-3 | 5g | $44 | 2026-04-30 | Buy |
PYRIDINE-2-THIOAMIDE Chemical Properties,Uses,Production
Uses
2-Pyridinecarbothioamide is a building block, that can be used for synthesis of Zn2+ responsive fluorescent probe[1].
Synthesis
100-70-9
5346-38-3
General Steps: a. Diphosphorus tetrasulfide (115 g, 0.5 mol) was slowly added to 250 mL of 20% ammonia in methanol solution containing 4-cyanopyridine (52 g, 0.5 mol) under vigorous stirring, ensuring that the temperature of the reaction mixture was maintained below 35-40°C. b. The reaction mixture was allowed to run for 12 hours at room temperature. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, 150 mL of water was added and the mixture was heated to 70-75 °C via a water bath until gas release ceased. After cooling to room temperature, the precipitate was collected by filtration, washed well with water and then dried. The product pyridine-2-carboxy sulfate amine was obtained in 89% yield (61.8 g) with an Rf value of 0.45 and a melting point of 137 °C (literature value: 136-137 °C). Elemental analysis result (%): C 52.09, H 4.31, N 20.30, S 23.30; theoretical value (C6H6N2S): C 52.15, H 4.38, N 20.27, S 23.20.
References
[1] Watanabe Y, et al. A zinc-responsive fluorophore based on 5′-(p-hydroxyphenyl)-pyridylthiazole[J]. Materials Chemistry Frontiers, 2020, 4(3): 899-904.
PYRIDINE-2-THIOAMIDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
PYRIDINE-2-THIOAMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28509 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
View Lastest Price from PYRIDINE-2-THIOAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | PYRIDINE-2-THIOAMIDE
5346-38-3
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-12 | PYRIDINE-2-THIOAMIDE
5346-38-3
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- PYRIDINE-2-THIOAMIDE
5346-38-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- PYRIDINE-2-THIOAMIDE
5346-38-3
- $1.00
- 99%
- Career Henan Chemical Co
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