2',5'-DIHYDROXYPROPIOPHENONE
- CAS No.
- 938-46-5
- Chemical Name:
- 2',5'-DIHYDROXYPROPIOPHENONE
- Synonyms
- 2-PROPIONYLHYDROQUINONE;Methoxamine Impurity 22;2,5-DIHYDROXYPROPIOPHENONE;Methoxamine Impurity 11 HCl;2',5'-DIHYDROXYPROPIOPHENONE;2’,5’-dihydroxy-propiophenon;Propiophenone, 2',5'-dihydroxy-;2',5'-Dihydroxypropiophenone,98%;1-(2,5-DIHYDROXYPHENYL)PROPAN-1-ONE;1-(2,5-Dihydroxyphenyl)-1-propanone
- CBNumber:
- CB3395464
- Molecular Formula:
- C9H10O3
- Molecular Weight:
- 166.17
- MDL Number:
- MFCD00016465
- MOL File:
- 938-46-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2',5'-DIHYDROXYPROPIOPHENONE AldrichCPR | S372315 | 1 unit | $152 |
| 2',5'-DIHYDROXYPROPIOPHENONE Aldrich | S372315 | 250mg | $139 |
| 2,5-Dihydroxypropiophenone | FD54147 | 100g | $500 |
| 2',5'-Dihydroxypropiophenone | Y1983 | 250g | $549 |
| 2',5'-DIHYDROXYPROPIOPHENONE 95.00% | COR0000627 | 1G | $1030.84 |
| Melting point | 95-99 °C |
|---|---|
| Boiling point | 254.38°C (rough estimate) |
| Density | 1.1708 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| pka | 8.96±0.48(Predicted) |
| BRN | 1938824 |
| CAS DataBase Reference | 938-46-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | MZ5ZW5SJ67 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26 | |||||||||
| RTECS | UH0420000 | |||||||||
| HS Code | 2914310000 | |||||||||
| NFPA 704 |
|
2',5'-DIHYDROXYPROPIOPHENONE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S372315 | 2',5'-DIHYDROXYPROPIOPHENONE AldrichCPR | 938-46-5 | 1 unit | $152 | 2026-03-19 | Buy |
| Sigma-Aldrich | S372315 | 2',5'-DIHYDROXYPROPIOPHENONE Aldrich | 938-46-5 | 250mg | $139 | 2024-03-01 | Buy |
| Biosynth Carbosynth | FD54147 | 2,5-Dihydroxypropiophenone | 938-46-5 | 100g | $500 | 2021-12-16 | Buy |
| AK Scientific | Y1983 | 2',5'-Dihydroxypropiophenone | 938-46-5 | 250g | $549 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | COR0000627 | 2',5'-DIHYDROXYPROPIOPHENONE 95.00% | 938-46-5 | 1G | $1030.84 | 2021-12-16 | Buy |
2',5'-DIHYDROXYPROPIOPHENONE Chemical Properties,Uses,Production
Chemical Properties
yellowish crystalline powder
Preparation
Preparation by Fries rearrangement of quinol dipropionate (hydroquinone dipropionate),
with aluminium chloride without solvent at 130–140° for 4 h (75%), at 142° for 30 min (80%), at 160–165° for 3 h (good yields) or at 190–200° for 90 min (60%)
by using various quantities of aluminium chloride at 180° for 2 h (to see below)
with aluminium chloride (2 equiv) in nitromethane at 20° for a week (7%) or in nitrobenzene (24%)
with boron trifluoride complex (BF 3-OBu2) at reflux for 1 h (42%)
by using titanium tetrachloride (2 equiv) at 130° for 2 h gave only 6% yield
Also obtained by treatment of
hydroquinone dipropionate with aluminium chloride in the presence of hyd- roquinone (61%)
2-hydroxy-5-(propionyloxy)propiophenone with aluminium chloride (5 equiv) at 180° for 30 min in the presence of hydroquinone (57%)
Also obtained by acylation of hydroquinone with propionic acid
in the presence of boron trifluoride in ethylene dichloride at 50–55° (59%) , in tetrachloroethane at 90–95° for 5 h (70%) or at 50° for 4 h (70%) or without solvent (67%) at 80° for 2 h (54%) or at 125° for 2 h (71%)
in the presence of zinc chloride at 190° few min (Nencki reaction)
in the presence of 70% perchloric acid at reflux for 1 h (12%)
Also obtained by Friedel–Crafts acylation of hydroquinone with propionyl chlo-ride in nitrobenzene in the presence of aluminium chloride (40%)
Also obtained from 2-hydroxy-5-(propionyloxy)propiophenone; the ester group elimination on hydrolysis with 85% sulfuric acid at r.t. or by treatment with by aluminium chloride
Also obtained by reaction of benzoquinone (2.5 equiv) with 2-oxobutanoic acid in aqueous acetonitrile or an acetonitrile/methylene chloride mixture (91%).
2',5'-DIHYDROXYPROPIOPHENONE Preparation Products And Raw materials
Raw materials
Preparation Products
2',5'-DIHYDROXYPROPIOPHENONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43416 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30123 | 84 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9815 | 79 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 86249 | 60 |
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