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Carboxymethyl cellulose

CAS No.
9000-11-7
Chemical Name:
Carboxymethyl cellulose
Synonyms
CMC;Carboxymethyl cellulose;croscarmellose;Carmellose;2,3,4,5,6-pentahydroxyhexanal;kmts;CM CELLULOSE;pentahydroxyhexanal;Carboxyl Methyl Cellulose;acetic acid,2,3,4,5,6-pentahydroxyhexanal
CBNumber:
CB3399316
Molecular Formula:
C6H12O6
Molecular Weight:
180.15588
MDL Number:
MFCD00149018
MOL File:
9000-11-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-04 11:17:55

Carboxymethyl cellulose Properties

Density 1.050 g/cm3(Temp: 15-18 °C)
FEMA 2239 | CARBOXYMETHYLCELLULOSE
storage temp. 2-8°C
solubility Practically insoluble in anhydrous ethanol. It swells with water to form a suspension and becomes viscid in 1 M sodium hydroxide.
form preswollen, microgranular
color White to off-white
Odor odorless
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Major Application pharmaceutical (small molecule)
Cosmetics Ingredients Functions BINDING
GEL FORMING
VISCOSITY CONTROLLING
BULKING
InChI InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2
InChIKey GZCGUPFRVQAUEE-UHFFFAOYSA-N
SMILES C(=O)C(O)C(O)C(O)C(O)CO
LogP -3.17
CAS DataBase Reference 9000-11-7(CAS DataBase Reference)
SCOGS (Select Committee on GRAS Substances) Carboxymethyl cellulose (packaging)
Substances Added to Food (formerly EAFUS) CARBOXYMETHYL CELLULOSE
FDA 21 CFR 175.105; 175.300
EWG's Food Scores 1
FDA UNII 05JZI7B19X
EPA Substance Registry System Cellulose, carboxymethyl ether (9000-11-7)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

WGK Germany  1
RTECS  FJ5700000
TSCA  TSCA listed
HS Code  3912310000
Storage Class 11 - Combustible Solids
Toxicity LD50 unreported in mammal (species unspecified): 13340mg/kg

Carboxymethyl cellulose price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001214 Carmellose European Pharmacopoeia (EP) Reference Standard 9000-11-7 10 mg $241 2026-04-30 Buy
Sigma-Aldrich 1096611 CM-Cellulose 9000-11-7 500mg $492 2026-04-30 Buy
Sigma-Aldrich Y0001214 Carmellose European Pharmacopoeia (EP) Reference Standard 9000-11-7 y0001214 $220 2024-03-01 Buy
Biosynth YC158179 Carboxymethyl cellulose 9000-11-7 250g $295 2026-06-05 Buy
Biosynth YC158179 Carboxymethyl cellulose 9000-11-7 500g $465 2026-06-05 Buy
Product number Packaging Price Buy
Y0001214 10 mg $241 Buy
1096611 500mg $492 Buy
Y0001214 y0001214 $220 Buy
YC158179 250g $295 Buy
YC158179 500g $465 Buy

Carboxymethyl cellulose Chemical Properties, Uses, Production

Product features

Carboxymethyl cellulose (CMC) is tackifier, at room temperature, it is non-toxic tasteless white flocculent powder, it is stable and soluble in water, aqueous solution is neutral or alkaline transparent viscous liquid, it is soluble in other water-soluble gums and resins, it is insoluble in organic solvents such as ethanol. Carboxymethyl cellulose is the substituted product of cellulosic carboxymethyl group. According to their molecular weight or degree of substitution, it can be completely dissolved or insoluble polymer, the latter can be used as the weak acid cation of exchanger to separate neutral or basic proteins.
Carboxymethyl cellulose can form highly viscous colloidal solution with adhesive, thickening, flowing, emulsifying, shaping, water, protective colloid, film forming, acid, salt, suspensions and other characteristics, and it is physiologically harmless, so it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.
Application: It is used in cigarette adhesive, fabric sizing, footwear paste meal, home slimy. It is used in interior painting architectural, building lines melamine, thickening mortar, concrete enhancement. It is used in refractory fiber, ceramic production molding bond. It is used in oil drilling, exploration address slurry thickening, reducing water loss, quality paper surface sizing. It can be used as soap and washing powder detergent active additives, as well as other industrial production on the dispersion, emulsification, stability, suspension, film, paper, polishing and the like. Quality product can be used for toothpaste, medicine, food and other industrial sectors.
Instructions: Warm water and cold water can be ok when prepares the solution, it can be used with stirring until it completely melts. The amout of added water depends on variety and the use of multiple requirements.
High viscosity sodium carboxymethyl cellulose (HV-CMC) is a white or slightly yellow fibrous powder, hygroscopic, odorless, tasteless, non-toxic, easy to ferment, insoluble in acids, alcohols and organic solvents, easily dispersed to form colloidal solution in water. It is reacted by the acid and fibrous cotton, it is mainly used for water-based drilling fluids tackifier, it has certain role of fluid loss, it has strong salt and temperature resistance especially.
The above information is edited by the chemicalbook of Wang Xiaodong.

Uses

CMC can significantly increase the viscosity of the solution as thickener, dispersion, emulsification, suspension, protective colloid and so on when it is dissolved in water, and it is physiologically harmless, it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.

Chemical Properties

White or almost white powder, hygroscopic.

Chemical Properties

Cellulose is a natural substance normally present in most diets because it is the major structural carbohydrate of green plants. Cellulose is essentially a linear polymer of glucopyranose units connected by α-1,4-glucoside links. In nature, cellulose is present in plant cell walls as fibers. The molecular weight of the isolated cellulose is approximately 50,000 daltons. The principal sources of cellulose for food-related purposes are cotton linters and wood pulp.
Chemical processing converts cellulose into forms or derivatives suitable for incorporation into food products or for use in food packaging materials. For food use, the optimum degree of substitution of a carboxymethyl-residue on each anhydroglucopyranose unit on cellulose is 0.95. By preliminary mild acid hydrolysis, the degree of polymerization (i.e., molecular size) of the cellulose may be reduced before carboxymethylation. Control of the degree of substitution and the degree of polymerization during processing results in production of a wide variety of derivatives that differ in such physical properties as gelling, temperature, viscosity and dispersibility in water. Sodium carboxymethyl cellulose is used as a thickening agent and stabilizer in foods. Because carboxymethyl cellulose is spontaneously converted to sodium salt in alkaline solution, it is probable that any distinction between carboxymethyl cellulose and sodium carboxymethyl cellulose in foodstuffs is artificial.*

Uses

Pharmaceutic aid (suspending agent); pharmaceutic aid (tablet excipient); pharmaceutic aid (viscosity-increasing agent).

Uses

carboxymethyl cellulose (cellulose gum) is a thickener. used in cosmetic formulations when a reactant is not required or desired. often used in bath preparations, beauty masks, hand creams, and shampoos. It is considered a non-comedogenic raw material.

Uses

Carboxymethylcellulose(CMC) is a gum that is water-soluble cellulose ether manufactured by reacting sodium monochloroacetate with alkali cellulose to form sodium . It dissolves in hot or cold water and is fairly stable over a pH range of 5.0–10.0, but acidification below pH 5.0 will reduce the viscosity and stability except in a special acid-stable type of CMC. A variety of types are available which differ in viscosity and degree of substitution (the number of sodium groups per unit). It functions as a thickener, stabilizer, binder, film former, and suspending agent. It is used in a variety of foods to include dressings, ice cream, baked goods, puddings, and sauces. The usage range is from 0.05 to 0.5%. Also termed cellulose gum.

Preparation

Sodium carboxymethyl cellulose is produced by treating wood pulp or cotton linters with alkali and monochloroacetic acid. It occurs as a white- or cream-colored powder or granules.

brand name

Celluvisc (Allergan); Refresh Plus, Cellufresh Formula (Allergan).

Industrial uses

Carboxymethyl cellulose is manufactured with molecular weights ranging from 50,000 to 800,000. Several modifications are of interest to flotation because they display good depressing properties for highly floatable magnesium-bearing minerals. These include sodium salts of phenolphthalein ether cellulose and ethanesulfo cellulose.

Industrial uses

Lignin sulfonate is used as dispersant, flocculant and depressant. Lignin is an amorphous polyphenolic compound derived from enzymatic polymerization of three phenylpropanoid monomers.

Carcinogenicity

Sarcomas were produced at the site of repeated subcutaneous injection of aqueous solutions of carboxymethylcellulose. It should be noted, however, that massive doses were given and therefore there must have been considerable local trauma.

Carboxymethyl cellulose Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 377)
Supplier Tel Email Country ProdList Advantage
Shandong Guanqing Food Ingredients Co., Ltd. 15138924569 15138924569 2551887798@qq.com China 123 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Beijing Baileisen Biotechnology Co., Ltd. 13581502185 joe0415zhaxi@163.com China 141 58
Shaoguan Xinrunhe Biotechnology Co., Ltd. 19022763608 19022763608 3873625718@qq.com China 1961 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6741 52
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79

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