ChemicalBook >> CAS DataBase List >>2-AMINO-5-PHENYLPYRIDINE

2-AMINO-5-PHENYLPYRIDINE

CAS No.
33421-40-8
Chemical Name:
2-AMINO-5-PHENYLPYRIDINE
Synonyms
PHE-P-1;AKOS BAR-1613;5-PHENYL-2-PYRIDINAMINE;5-Phenyl-2-aminopyridine;2-amino-5-phenyl-pyridin;2-AMINO-5-PHENYLPYRIDINE;2-pyridinaMine, 5-phenyl-;5-PHENYL-PYRIDIN-2-YLAMINE;2-Amino-5-phenylpyridine,97%;2-Amino-5-phenylpyridine >
CBNumber:
CB3401529
Molecular Formula:
C11H10N2
Molecular Weight:
170.21
MDL Number:
MFCD01692452
MOL File:
33421-40-8.mol
MSDS File:
SDS
Last updated:2026-01-13 11:18:30
Product description Number Pack Size Price
2-Amino-5-phenylpyridine >98.0%(GC)(T) A1667 1g $294
2-Amino-5-phenylpyridine >98.0%(GC)(T) A1667 100mg $47
2-Amino-5-phenylpyridine A626745 2.5g $215
2-Amino-5-phenylpyridine 97% 3H30-1-KS 5G $311
2-Amino-5-phenylpyridine >97.0% CS-W002820 5g $71
More product size

2-AMINO-5-PHENYLPYRIDINE Properties

Melting point 132 °C
Boiling point 324℃
Density 1.133
refractive index 1.5200 (estimate)
Flash point 176℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 6.32±0.13(Predicted)
form Solid
color Off-White to Light Yellow
InChI 1S/C11H10N2/c12-11-7-6-10(8-13-11)9-4-2-1-3-5-9/h1-8H,(H2,12,13)
InChIKey OAPVIBHQRYFYSE-UHFFFAOYSA-N
SMILES Nc1ccc(cn1)-c2ccccc2
CAS DataBase Reference 33421-40-8(CAS DataBase Reference)
FDA UNII BJY2E567LB
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H335-H351-H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280h-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-36-22-40
Safety Statements  26-36/37/39-36/37
WGK Germany  WGK 3
RTECS  US2145000
HS Code  29333990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2
Toxicity mma-sat 100 mg/plate CPBTAL 26,611,78
NFPA 704
0
2 0

2-AMINO-5-PHENYLPYRIDINE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1667 2-Amino-5-phenylpyridine >98.0%(GC)(T) 33421-40-8 1g $294 2026-04-30 Buy
TCI Chemical A1667 2-Amino-5-phenylpyridine >98.0%(GC)(T) 33421-40-8 100mg $47 2026-04-30 Buy
TRC A626745 2-Amino-5-phenylpyridine 33421-40-8 2.5g $215 2021-12-16 Buy
SynQuest Laboratories 3H30-1-KS 2-Amino-5-phenylpyridine 97% 33421-40-8 5G $311 2021-12-16 Buy
ChemScene CS-W002820 2-Amino-5-phenylpyridine >97.0% 33421-40-8 5g $71 2021-12-16 Buy
Product number Packaging Price Buy
A1667 1g $294 Buy
A1667 100mg $47 Buy
A626745 2.5g $215 Buy
3H30-1-KS 5G $311 Buy
CS-W002820 5g $71 Buy

2-AMINO-5-PHENYLPYRIDINE Chemical Properties,Uses,Production

Chemical Properties

Beige Crystalline Solid

Uses

A product from the pyrolysis of phenylalanine

Definition

ChEBI: 5-Phenyl-2-pyridinamine is a phenylpyridine.

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

Synthesis

2-CHLORO-5-PHENYLPYRIDINE

66600-05-3

2-AMINO-5-PHENYLPYRIDINE

33421-40-8

The general procedure for the synthesis of 2-amino-5-phenylpyridine from 2-chloro-5-phenylpyridine is as follows: 1. a solution was prepared by dissolving 2-chloro-5-phenylpyridine (4.0 g, 0.021 mol) in anhydrous ether (160 ml). 2. the above solution was slowly added dropwise to a solution of liquid ammonia (160 ml) containing sodium (3.39 g, 0.15 g atoms) and ferrous nitrate hexahydrate (0.095 g). 3. The resulting suspension was heated to reflux for 4 hours. 4. Upon completion of the reaction, ammonium chloride was added and the ammonia was allowed to evaporate naturally. 5. The residue is treated with a 5% aqueous sodium hydroxide solution (5 mL). 6. Filter the mixture to separate the solids from the liquid. 7. Extract the aqueous layer with ether (2 x 100 ml) and combine the ether layers. 8. Wash the combined ether layers with brine and dry with sodium sulfate. 9. The dried ether solution was concentrated to give the crude product. 10. the crude product was recrystallized with methylcyclohexane. 11. 11. The recrystallized product was ground with chloroform (100 ml). 12. The mixture was filtered and the filtrate was evaporated to give the final product 2-amino-5-phenylpyridine (1.3 g, 36% yield) with a melting point of 205 °C. Melting points of 133°-135° have been reported in the literature (Chem. Ber., 91, 247 (1958)).

References

[1] Patent: US4122274, 1978, A

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View Lastest Price from 2-AMINO-5-PHENYLPYRIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-5-PHENYLPYRIDINE  pictures 2025-11-18 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-AMINO-5-PHENYLPYRIDINE pictures 2024-08-24 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
US $1.00 / kg 1kg 99% 100kg Zhengzhou HQ Material CO.,LTD.
2-AMINO-5-PHENYLPYRIDINE pictures 2019-12-26 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
US $1.00 / KG 1KG 99% 1000KGS Career Henan Chemical Co

2-AMINO-5-PHENYLPYRIDINE Spectrum

2-amino-5-phenyl-pyridin 5-PHENYL-2-PYRIDINAMINE 5-PHENYL-PYRIDIN-2-YLAMINE AKOS BAR-1613 2-AMINO-5-PHENYLPYRIDINE PHE-P-1 2-Amino-5-phenylpyridine,97% 2-pyridinaMine, 5-phenyl- 2-Amino-5-phenylpyridine > 2-AMINO-5-PHENYLPYRIDINE ISO 9001:2015 REACH 5-Phenyl-2-aminopyridine 33421-40-8 Amines Heterocycles pharmacetical Aromatics Compounds Aromatics