2-AMINO-5-PHENYLPYRIDINE
- CAS No.
- 33421-40-8
- Chemical Name:
- 2-AMINO-5-PHENYLPYRIDINE
- Synonyms
- PHE-P-1;AKOS BAR-1613;5-PHENYL-2-PYRIDINAMINE;5-Phenyl-2-aminopyridine;2-amino-5-phenyl-pyridin;2-AMINO-5-PHENYLPYRIDINE;2-pyridinaMine, 5-phenyl-;5-PHENYL-PYRIDIN-2-YLAMINE;2-Amino-5-phenylpyridine,97%;2-Amino-5-phenylpyridine >
- CBNumber:
- CB3401529
- Molecular Formula:
- C11H10N2
- Molecular Weight:
- 170.21
- MDL Number:
- MFCD01692452
- MOL File:
- 33421-40-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-5-phenylpyridine >98.0%(GC)(T) | A1667 | 1g | $294 |
| 2-Amino-5-phenylpyridine >98.0%(GC)(T) | A1667 | 100mg | $47 |
| 2-Amino-5-phenylpyridine | A626745 | 2.5g | $215 |
| 2-Amino-5-phenylpyridine 97% | 3H30-1-KS | 5G | $311 |
| 2-Amino-5-phenylpyridine >97.0% | CS-W002820 | 5g | $71 |
| More product size | |||
| Melting point | 132 °C |
|---|---|
| Boiling point | 324℃ |
| Density | 1.133 |
| refractive index | 1.5200 (estimate) |
| Flash point | 176℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 6.32±0.13(Predicted) |
| form | Solid |
| color | Off-White to Light Yellow |
| InChI | 1S/C11H10N2/c12-11-7-6-10(8-13-11)9-4-2-1-3-5-9/h1-8H,(H2,12,13) |
| InChIKey | OAPVIBHQRYFYSE-UHFFFAOYSA-N |
| SMILES | Nc1ccc(cn1)-c2ccccc2 |
| CAS DataBase Reference | 33421-40-8(CAS DataBase Reference) |
| FDA UNII | BJY2E567LB |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H351-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280h-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-36-22-40 | |||||||||
| Safety Statements | 26-36/37/39-36/37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| RTECS | US2145000 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 |
|||||||||
| Toxicity | mma-sat 100 mg/plate CPBTAL 26,611,78 | |||||||||
| NFPA 704 |
|
2-AMINO-5-PHENYLPYRIDINE price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A1667 | 2-Amino-5-phenylpyridine >98.0%(GC)(T) | 33421-40-8 | 1g | $294 | 2026-04-30 | Buy |
| TCI Chemical | A1667 | 2-Amino-5-phenylpyridine >98.0%(GC)(T) | 33421-40-8 | 100mg | $47 | 2026-04-30 | Buy |
| TRC | A626745 | 2-Amino-5-phenylpyridine | 33421-40-8 | 2.5g | $215 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3H30-1-KS | 2-Amino-5-phenylpyridine 97% | 33421-40-8 | 5G | $311 | 2021-12-16 | Buy |
| ChemScene | CS-W002820 | 2-Amino-5-phenylpyridine >97.0% | 33421-40-8 | 5g | $71 | 2021-12-16 | Buy |
2-AMINO-5-PHENYLPYRIDINE Chemical Properties,Uses,Production
Chemical Properties
Beige Crystalline Solid
Uses
A product from the pyrolysis of phenylalanine
Definition
ChEBI: 5-Phenyl-2-pyridinamine is a phenylpyridine.
Safety Profile
Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.
Synthesis
66600-05-3
33421-40-8
The general procedure for the synthesis of 2-amino-5-phenylpyridine from 2-chloro-5-phenylpyridine is as follows: 1. a solution was prepared by dissolving 2-chloro-5-phenylpyridine (4.0 g, 0.021 mol) in anhydrous ether (160 ml). 2. the above solution was slowly added dropwise to a solution of liquid ammonia (160 ml) containing sodium (3.39 g, 0.15 g atoms) and ferrous nitrate hexahydrate (0.095 g). 3. The resulting suspension was heated to reflux for 4 hours. 4. Upon completion of the reaction, ammonium chloride was added and the ammonia was allowed to evaporate naturally. 5. The residue is treated with a 5% aqueous sodium hydroxide solution (5 mL). 6. Filter the mixture to separate the solids from the liquid. 7. Extract the aqueous layer with ether (2 x 100 ml) and combine the ether layers. 8. Wash the combined ether layers with brine and dry with sodium sulfate. 9. The dried ether solution was concentrated to give the crude product. 10. the crude product was recrystallized with methylcyclohexane. 11. 11. The recrystallized product was ground with chloroform (100 ml). 12. The mixture was filtered and the filtrate was evaporated to give the final product 2-amino-5-phenylpyridine (1.3 g, 36% yield) with a melting point of 205 °C. Melting points of 133°-135° have been reported in the literature (Chem. Ber., 91, 247 (1958)).
References
[1] Patent: US4122274, 1978, A
2-AMINO-5-PHENYLPYRIDINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Zhengzhou HQ Material CO.,LTD. | +86-371-55919009 +8615225108189 | sale1@hqmat.com | China | 1001 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 2-AMINO-5-PHENYLPYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2024-08-24 | 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
|
US $1.00 / kg | 1kg | 99% | 100kg | Zhengzhou HQ Material CO.,LTD. | |
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2019-12-26 | 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
|
US $1.00 / KG | 1KG | 99% | 1000KGS | Career Henan Chemical Co |
-

- 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-

- 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
- US $1.00 / kg
- 99%
- Zhengzhou HQ Material CO.,LTD.
-

- 2-AMINO-5-PHENYLPYRIDINE
33421-40-8
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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