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BNP-32 (RAT)

CAS No.
133448-20-1
Chemical Name:
BNP-32 (RAT)
Synonyms
BNP RAT;BNP-32 (RAT);BNP (1-32) RAT;BNP (51-95), RAT;BNP-32 (rat) trifluoroacetate;NSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF;Brain Natriuretic Peptide (1-32);BRAIN NATRIURETIC PEPTIDE-32 (RAT);Rat brain natriuretic peptide(1-32);BRAIN NATRIURETIC PEPTIDE (1-32), RAT
CBNumber:
CB3403598
Molecular Formula:
C146H239N47O44S3
Molecular Weight:
3452.94
MDL Number:
MFCD00133150
MOL File:
133448-20-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:56:55

BNP-32 (RAT) Properties

Density 1.50±0.1 g/cm3(Predicted)
storage temp. -20°C
form powder
Water Solubility Soluble in Water
Sequence Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys-Asp-Gly-Leu-Arg-Leu-Phe (Disulfide bridge: Cys10-Cys26)
InChIKey CKSKSHHAEYGHSB-LBCJMRPYSA-N
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
Storage Class 11 - Combustible Solids

BNP-32 (RAT) price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FB109674 BNP-32 (rat) trifluoroacetate 133448-20-1 250ug $900 2026-06-04 Buy
Biosynth FB109674 BNP-32 (rat) trifluoroacetate 133448-20-1 100ug $900 2026-06-04 Buy
Biosynth FB109674 BNP-32 (rat) trifluoroacetate 133448-20-1 50ug $900 2026-06-04 Buy
Biosynth FB109674 BNP-32 (rat) trifluoroacetate 133448-20-1 500ug $990 2026-06-04 Buy
Biosynth FB109674 BNP-32 (rat) trifluoroacetate 133448-20-1 1000ug $1720 2026-06-04 Buy
Product number Packaging Price Buy
FB109674 250ug $900 Buy
FB109674 100ug $900 Buy
FB109674 50ug $900 Buy
FB109674 500ug $990 Buy
FB109674 1000ug $1720 Buy

BNP-32 (RAT) Chemical Properties, Uses, Production

Uses

Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes)[1].

Biochem/physiol Actions

Brain natriuretic peptide (type B natriuretic peptide) was originally isolated from brain, but is mainly produced in myoendocrine cells of the heart ventricles from which it is released into the circulation. It is involved in blood pressure control and cardiovascular homeostasis.

in vivo

The depressor, natriuretic and cyclic GMP responses to several species of brain natriuretic peptide (BNP) are compared to atrial natriureticpeptide (ANP) 99-126 in conscious spontaneously hypertensive rats (SHR) and in conscious cynomolgus monkeys treated with vehicle or the selective neutral endopeptidase inhibitor SQ 28603. In the conscious SHR, the natriuretic and cyclic GMP responses to 3 nmol/kg i.v. rat BNP (1-32) greater than rat ANP 99-126 greater than pig BNP-26 and sre significantly potentiated by 100 mumol/kg i.v. SQ 28,603. Human BNP-32 is inactive in the SHR treated with either vehicle or SQ 28,603. In contrast, 1 nmol/kg i.v. of human BNP (1-32) stimulates renal and depressor responses in the conscious monkeys that are greater than or equal to those elicited by human ANP 99-126, whereas 3 nmol/kg i.v. rat BNP (1-32) reduces mean arterial pressure without affecting renal function[3].

References

[1] Dickey DM, et al. Human B-type natriuretic peptide is not degraded by meprin A. Biochem Pharmacol. 2010 Oct 1;80(7):1007-11. DOI:10.1016/j.bcp.2010.06.015
[2] Wellard J, et al. Natriuretic peptides, but not nitric oxide donors, elevate levels of cytosolic guanosine 3',5'-cyclic monophosphate in ependymal cells ex vivo. Neurosci Lett. 2006 Jan 16;392(3):187-92. DOI:10.1016/j.neulet.2005.09.084
[3] Seymour AA, et al. Potentiation of brain natriuretic peptides by SQ 28,603, an inhibitor of neutral endopeptidase3.4.24.11, in monkeys and rats. J Pharmacol Exp Ther. 1992 Jul;262(1):60-70. PMID:1385630

BNP-32 (RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

BNP-32 (RAT) Suppliers

Global Suppliers ( 98)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Cellmano Biotech Limited 0551-65326643 18156095617 info@cellmano.com China 1010 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Creative Peptides info@creative-peptides.com United States 6083 56
Shanghai Xilong Biochemical Technology Co., Ltd. 021-52907766-8042 China 9928 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
H-ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE-OH H-ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE-OH (DISULFIDE BRIDGE: 10-26) H-ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE-OH, (DISULFIDE BOND) B-TYPE (BRAIN) NATRIURETIC PEPTIDE-32 (RAT) BRAIN NATRIURETIC PEPTIDE-32 (RAT) BRAIN NATRIURETIC PEPTIDE (1-32), RAT BNP (1-32) RAT BNP RAT BNP (51-95), RAT BNP-32 (RAT) ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE NSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF NSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF (DISULFIDE BRIDGE: 10-26) 14-45-Brain natriuretic peptide-45 (rat) Rat brain natriuretic peptide(1-32) L-Asn-L-Ser-L-Lys-L-Met-L-Ala-L-His-L-Ser-L-Ser-L-Ser-L-Cys(1)-L-Phe-Gly-L-Gln-L-Lys-L-Ile-L-Asp-L-Arg-L-Ile-Gly-L-Ala-L-Val-L-Ser-L-Arg-L-Leu-Gly-L-Cys(1)-L-Asp-Gly-L-Leu-L-Arg-L-Leu-L-Phe-OH ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP- GLY-LEU-ARG-LEU-PHE(DISULFIDE BRIDGE:CYS10-CYS26) BNP-32 (rat) Brain Natriuretic Peptide-32 (rat) BNP-32 (rat) trifluoroacetate Brain Natriuretic Peptide (BNP) (1-32), rat Brain natriuretic peptide-32 rat, ≥97% (HPLC) 14-45-Brain natriuretic peptide-45 (rat) (9CI) Brain Natriuretic Peptide-32 rat >=97% (HPLC), powder Brain Natriuretic Peptide (1-32) ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE 133448-20-1 C146H239N47O44S3 BioChemical Amino Acids and Peptides Biochemicals and Reagents Natriuretic Peptides Peptides Peptide