Deoxycorticosterone acetate
- CAS No.
- 56-47-3
- Chemical Name:
- Deoxycorticosterone acetate
- Synonyms
- DESOXYCORTONE ACETATE;DESOXYCORTICOSTERONE ACETATE;DOCA;DOAC;3,20-Dioxopregn-4-en-21-yl acetate;doxo;arcort;steraq;cortate;ocriten
- CBNumber:
- CB3462948
- Molecular Formula:
- C23H32O4
- Molecular Weight:
- 372.5
- MDL Number:
- MFCD00003660
- MOL File:
- 56-47-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 157°C |
|---|---|
| alpha | D20 +168 to +176° (dioxane) |
| Boiling point | 421.94°C (rough estimate) |
| Density | 1.0415 (rough estimate) |
| refractive index | 175 ° (C=1, Dioxane) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: insoluble |
| form | Solid |
| color | White to Off-White |
| biological source | synthetic (organic) |
| Water Solubility | 4mg/L(25 ºC) |
| Merck | 2901 |
| BRN | 2570798 |
| InChI | InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1 |
| InChIKey | VPGRYOFKCNULNK-ACXQXYJUSA-N |
| SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2 |
| LogP | 3.080 |
| CAS DataBase Reference | 56-47-3(CAS DataBase Reference) |
| FDA UNII | 6E0A168OB8 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H373-H360 |
| Precautionary statements | P260-P314-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | HG0525000 |
| HazardClass | IRRITANT |
| HS Code | 2937290000 |
| Storage Class | 11 - Combustible Solids |
Deoxycorticosterone acetate price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 1g | $228 | 2026-04-30 | Buy |
| Sigma-Aldrich | D0400000 | Desoxycortone acetate European Pharmacopoeia (EP) Reference Standard | 56-47-3 | 100 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1174001 | Deoxycorticosterone acetate United States Pharmacopeia (USP) Reference Standard | 56-47-3 | 200mg | $422 | 2026-04-30 | Buy |
| Cayman Chemical | 30856 | Deoxycorticosterone Acetate ≥95% | 56-47-3 | 1g | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 30856 | Deoxycorticosterone Acetate ≥95% | 56-47-3 | 5g | $190 | 2026-04-30 | Buy |
Deoxycorticosterone acetate Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Adrenocortical/mineralocorticoid Steroid.
Uses
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Definition
ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.
brand name
Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].
General Description
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.
Purification Methods
11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]
Deoxycorticosterone acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Hangzhou Zyter Biological & Chemical Technology Co., Ltd. | 18858184290; | sales@zyterpharm.com | China | 47 | 49 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| RYSS TECH LTD | 400-188-0725 +86 21 34310725 13611771617 | China | 1999 | 57 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Aemon Chemical | 0086-755-86198205 | acinfo@aemonchem.com | China | 1928 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
View Lastest Price from Deoxycorticosterone acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Deoxycorticosterone acetate
56-47-3
|
1kg | 99.1 | 100KG | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-20 | Deoxycorticosterone acetate
56-47-3
|
$30.00-40.00 | 99.19% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-09-14 | Deoxycorticosterone acetate
56-47-3
|
1kg | 99% | 50tons | Wuhan Han Sheng New Material Technology Co.，Ltd |
-
- Deoxycorticosterone acetate
56-47-3
- 99.1
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Deoxycorticosterone acetate
56-47-3
- $30.00-40.00
- 99.19%
- TargetMol Chemicals Inc.
-
- Deoxycorticosterone acetate
56-47-3
- 99%
- Wuhan Han Sheng New Material Technology Co.，Ltd
