HUMAN VEGF165
- CAS No.
- 127464-60-2
- Chemical Name:
- HUMAN VEGF165
- Synonyms
- VEGF;RECOMBINANT HUMAN VEGF165;VASCULAR ENDOTHELIAL GROWTH FACTOR, HUMAN;Vascular Endothelial Growth Factor (aa 207-318) human;VPF;mVEGF;MVCD1;RHVPF;RHVEGF;VEGF112
- CBNumber:
- CB3470679
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MDL Number:
- MFCD00286542
- MOL File:
- Mol file
- MSDS File:
- SDS
| storage temp. | -20°C |
|---|---|
| form | powder |
| color | white |
| biological source | rat |
| Cosmetics Ingredients Functions |
HAIR CONDITIONING SKIN CONDITIONING |
| NCI Dictionary of Cancer Terms | vascular endothelial growth factor; VEGF |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
HUMAN VEGF165 price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V7259 | Vascular Endothelial Growth Factor human VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture | 127464-60-2 | 10μg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | V3388 | Vascular Endothelial Growth Factor (aa 207-318) human ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder | 5μG | $791 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SRP3182 | VEGF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 127464-60-2 | 10μG | $470 | 2026-04-30 | Buy |
| Sigma-Aldrich | SAB2502119 | Anti-VEGFA antibody produced in goat affinity isolated antibody, buffered aqueous solution | 127464-60-2 | 100μG | $628 | 2026-04-30 | Buy |
| Sigma-Aldrich | SAB1306008 | ANTI-VEGF1(N-TERMINAL) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 127464-60-2 | 400μL | $532 | 2026-04-30 | Buy |
HUMAN VEGF165 Chemical Properties, Uses, Production
Uses
VEGF human has been used as a chemoattractant for HUVECs (human umbilical vein endothelial cells) migration assay.
General Description
VEGF (vascular endothelial growth factor) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biochem/physiol Actions
VEGF (vascular endothelial growth factor) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intraocular neovascular syndromes. Polymorphism in VEGF at C(-634)G is linked with diabetic retinopathy in type 2 diabetes.
Description
Vascular Endothelial Growth Factor Human Recombinant produced in E.Coli is a double, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 38.2kDa.
The VEGF is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Vascular endothelial growth factor (VEGF) is an important signaling protein involved in vessel formation As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ). VEGF mediates increased vascular permeability, induces vasculogenesis and endothelial cell production, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. VEGF is located in normal cartilage though only osteoarthritic cartilage expresses the VEGF receptors, NP1, VEGFR1 and VEGFR2. The VEGF level in the culture media from OA chondrocytes was more than 3 folds higher than in media from normal chondrocytes
HUMAN VEGF165 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Beijing OKA biological technology co., LTD | 010-62971590 18548936886 | 3462612863@qq.com | China | 10061 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 17754423994 | candy@biochempartner.com | China | 3057 | 58 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821; | sales@klbio.cn | China | 9619 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
