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HPV16 E7(86-93)

CAS No.
160212-93-1
Chemical Name:
HPV16 E7(86-93)
Synonyms
HPV16 E7(86-93);Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile;L-Isoleucine, L-threonyl-L-leucylglycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl-
CBNumber:
CB34713725
Molecular Formula:
C37H66N8O10S
Molecular Weight:
815.03
MDL Number:
MFCD32068004
MOL File:
160212-93-1.mol
Last updated:2025-06-18 16:39:23

HPV16 E7(86-93) Properties

Boiling point 1168.2±65.0 °C(Predicted)
Density 1.210±0.06 g/cm3(Predicted)
pka 3.72±0.22(Predicted)
Sequence Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile

HPV16 E7(86-93) Chemical Properties,Uses,Production

Uses

HPV16 E7 (86-93) is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. HPV16 E7 (86-93) is immunogenic in cervical carcinomas[1][2].

in vivo

HPV16 E7 (86-93) peptide in IVS culture has specific T cell expansion. The HPV16 E7 (86-93) specific T cells produced does not recognize naturally HPV16 E7 expressing cell line CaSki. HPV16 E7 (86-93) peptides also has similar observations in transgenic mice. The HPV16 E7 (86-93) peptide is able to induce cytotoxic T lymphocyte (CTL) responses if loaded on the antigen presenting HLA class I molecules, but that the peptide appears not to be processed or presented by HPV16 infected cells[1].

References

[1] Cheng WF, et al. Induction of human papillomavirus type 16-specific immunologic responses in a normal and an human papillomavirus-infected populations. Immunology. 2005 May;115(1):136-49. DOI:10.1111/j.1365-2567.2005.02126.x
[2] Hoffmann TK, et al. T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx. Int J Cancer. 2006 Apr 15;118(8):1984-91. DOI:10.1002/ijc.21565

HPV16 E7(86-93) Preparation Products And Raw materials

Raw materials

Preparation Products

HPV16 E7(86-93) Suppliers

Global( 16)Suppliers
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HPV16 E7(86-93) Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile L-Isoleucine, L-threonyl-L-leucylglycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl- 160212-93-1