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3-Chloro-2-fluoro-pyridine

3-Chloro-2-fluoro-pyridine structure

CAS No.: 1480-64-4

Chemical Name:: 3-Chloro-2-fluoro-pyridine

Synonyms: 3-CHLORO-2-FLUOROPYRIDINE;2-Fluoro-3-chloro pyridine;Pyridine, 3-chloro-2-fluoro-;3-Chloro-2-fluoropyridine >3-Chloro-2-fluoro-pyridine ISO 9001：2015 REACH

CBNumber:: CB3471904

Molecular Formula:: C5H3ClFN

Molecular Weight:: 131.54

MDL Number:: MFCD04114144

MOL File:: 1480-64-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:11:56

Product description	Number	Pack Size	Price
3-Chloro-2-fluoropyridine >98.0%(GC)	C2515	5g	$46
3-Chloro-2-fluoropyridine >98.0%(GC)	C2515	25g	$153
3-Chloro-2-fluoropyridine Asreported	270325	2g	$333
3-Chloro-2-fluoropyridine Asreported	270325	5g	$536
3-Chloro-2-fluoropyridine Asreported	270325	10g	$738
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3-Chloro-2-fluoro-pyridine Properties

Boiling point	162℃
Density	1.33
Flash point	52°(126°F)
refractive index	1.5030
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	clear liquid
pka	-2.71±0.10(Predicted)
color	Colorless to Almost colorless
InChI	InChI=1S/C5H3ClFN/c6-4-2-1-3-8-5(4)7/h1-3H
InChIKey	IHGMHTQDGNVKTA-UHFFFAOYSA-N
SMILES	C1(F)=NC=CC=C1Cl
CAS DataBase Reference	1480-64-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07,GHS05

Signal word

Warning

Hazard statements

H226-H302+H312+H332-H315-H319-H302-H312-H314-H318-H332

Precautionary statements

P303+P361+P353-P305+P351+P338-P310-P210-P233-P240-P241+P242+P243-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P403+P235-P501

Hazard Codes

T,Xn

Risk Statements

22-37/38-41-34-20/21/22-10

Safety Statements

26-39-45-36/37/39

RIDADR

2924

HazardClass

PackingGroup

III

HS Code

29333990

NFPA 704

	2
3		0

3-Chloro-2-fluoro-pyridine price More Price(61)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C2515	3-Chloro-2-fluoropyridine >98.0%(GC)	1480-64-4	5g	$46	2026-04-30	Buy
TCI Chemical	C2515	3-Chloro-2-fluoropyridine >98.0%(GC)	1480-64-4	25g	$153	2026-04-30	Buy
Usbiological	270325	3-Chloro-2-fluoropyridine Asreported	1480-64-4	2g	$333	2026-06-03	Buy
Usbiological	270325	3-Chloro-2-fluoropyridine Asreported	1480-64-4	5g	$536	2026-06-03	Buy
Usbiological	270325	3-Chloro-2-fluoropyridine Asreported	1480-64-4	10g	$738	2026-06-03	Buy

Product number	Packaging	Price	Buy
C2515	5g	$46	Buy
C2515	25g	$153	Buy
270325	2g	$333	Buy
270325	5g	$536	Buy
270325	10g	$738	Buy

3-Chloro-2-fluoro-pyridine Chemical Properties,Uses,Production

Uses

3-Chloro-2-fluoropyridine is used as a reactant in the synthesis of several compounds with therapeutic potential.

Synthesis

2402-77-9

1480-64-4

GENERAL METHOD: To a solution of 2,3-dichloropyridine (1.00 g, 6.76 mmol) in dimethyl sulfoxide (DMSO, 33.8 mL) was added cesium fluoride (CsF, 2.053 g, 13.51 mmol) at room temperature. The reaction mixture was stirred in air at 110 °C for 20 hours. After completion of the reaction, the reaction mixture was quenched with ice water and extracted with ethyl acetate (EtOAc). The organic layer was separated, washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The residue was purified by silica gel column chromatography using ethyl acetate (EtOAc) in hexane as eluent to afford 3-chloro-2-fluoropyridine (0.639 g, 4.86 mmol, 71.9% yield) as a colorless oil. Compounds 3B'-8B' were prepared by a method similar to the synthetic procedure for compound 2B'.

References

[1] Tetrahedron Letters, 2015, vol. 56, # 44, p. 6043 - 6046
[2] Angewandte Chemie - International Edition, 2006, vol. 45, # 17, p. 2720 - 2725
[3] Patent: EP1595867, 2005, A1. Location in patent: Page/Page column 33-34
[4] Organic Letters, 2015, vol. 17, # 8, p. 1866 - 1869
[5] Patent: EP1726590, 2006, A1. Location in patent: Page/Page column 56

3-Chloro-2-fluoro-pyridine synthesis

Synthesis of 3-Chloro-2-fluoro-pyridine from 2,3-Dichloropyridine

3-Chloro-2-fluoro-pyridine Preparation Products And Raw materials

Raw materials

2,3-Dichloropyridine Caesium fluoride Dimethyl sulfoxide

Preparation Products

2,4-DIFLUORO-PYRIDINE 3,4-Dichloro-2-fluoropyridine 3-Chloro-2,4-difluoropyridine

3-Chloro-2-fluoro-pyridine Suppliers

Global( 223)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Dongfan Chem. Co., Ltd.	021-34500607 13391355195	sales@dfanchem.com	CHINA	61	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Dongfan Chem. Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 3-Chloro-2-fluoro-pyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	3-Chloro-2-fluoro-pyridine 1480-64-4	$10.00	1KG	99%	5tons	Hebei Chuanghai Biotechnology Co., Ltd
2025-06-25	3-Chloro-2-fluoro-pyridine 1480-64-4	$1.10	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2024-04-27	3-Chloro-2-fluoropyridine 1480-64-4	$5.00	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd

3-Chloro-2-fluoro-pyridine
1480-64-4
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

3-Chloro-2-fluoro-pyridine
1480-64-4
$1.10
99.0% min
Shaanxi Dideu Medichem Co. Ltd

3-Chloro-2-fluoropyridine
1480-64-4
$5.00
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

3-Chloro-2-fluoro-pyridine Spectrum

3-Chloro-2-fluoro-pyridine(1480-64-4)¹HNMR

1480-64-4(3-Chloro-2-fluoro-pyridine)Related Search:

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2-Fluoro-3-chloro pyridine 3-Chloro-2-fluoropyridine > Pyridine, 3-chloro-2-fluoro- 3-Chloro-2-fluoro-pyridine ISO 9001：2015 REACH 3-CHLORO-2-FLUOROPYRIDINE 1480-64-4 Fluorine series Pyridine Pyridines